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Original Article

Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer

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Pages 1037-1045 | Accepted 11 Feb 2010, Published online: 03 Mar 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Josep Darbà, Lisette Kaskens & Rainel Sánchez-de la Rosa. (2014) Budget impact analysis of the fentanyl buccal tablet for treatment of breakthrough cancer pain. ClinicoEconomics and Outcomes Research 6, pages 1-9.
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Daniele Santini, Gaetano Lanzetta, Emanuela Dell'Aquila, Bruno Vincenzi, Olga Venditti, Marco Russano, Nicola Papapietro, Vincenzo Denaro, Giuseppe Tonini & Carla Ripamonti. (2013) ‘Old' and ‘new' drugs for the treatment of cancer pain. Expert Opinion on Pharmacotherapy 14:4, pages 425-433.
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Sebastiano Mercadante. (2011) Prospects and challenges in opioid analgesia for pain management. Current Medical Research and Opinion 27:9, pages 1741-1743.
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Mellar P Davis. (2011) Fentanyl for breakthrough pain: a systematic review. Expert Review of Neurotherapeutics 11:8, pages 1197-1216.
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Wojciech Leppert. (2010) Role of intranasal fentanyl in breakthrough pain management in cancer patients. Cancer Management and Research 2, pages 225-232.
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Articles from other publishers (40)

Jacopo Giuliani, Francesco Fiorica, Alfredo Sacchetto, Gianfranco Franceschini, Ferdinando Vaccari & Andrea Bonetti. (2020) The role of fentanyl in the treatment of breakthrough cancer pain: Different biotechnologies, different results and different drug costs. Journal of Oncology Pharmacy Practice 27:2, pages 445-447.
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Srinivas R. Banala, Osama K. Khattab, Valda D. Page, Carla L. Warneke, Knox H. Todd & Sai-Ching Jim Yeung. (2020) Intranasal fentanyl spray versus intravenous opioids for the treatment of severe pain in patients with cancer in the emergency department setting: A randomized controlled trial. PLOS ONE 15:7, pages e0235461.
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Klaus Ruberg & Matthias Thöns. 2019. Repetitorium Palliativmedizin. Repetitorium Palliativmedizin 297 330 .
Michael A. Überall. (2017) Transmukosale Applikation von Fentanyl: sublingual, buccal, nasal — egal?Transmucosal fentanyl administration: sublingual, buccal, nasal — all the same? Treatment of breakthrough cancer pain. MMW - Fortschritte der Medizin 159:S6, pages 15-22.
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Luis Cabezón-Gutiérrez, María Aurora Viloria-Jiménez, Juan Pérez-Cajaraville, Cecilio Álamo-González, José Antonio López-Trigo & Pedro Gil-Gregorio. (2017) Dolor irruptivo oncológico en el anciano. Revista Española de Geriatría y Gerontología 52:5, pages 271-277.
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Jeannine Brant, Barbara Rodgers, Eva Gallagher & Thiruppavai Sundaramurthi. (2017) Breakthrough Cancer Pain: A Systematic Review of Pharmacologic Management
. Clinical Journal of Oncology Nursing 21:3, pages 71-80.
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Stephan A. Schug & Sonya Ting. (2017) Fentanyl Formulations in the Management of Pain: An Update. Drugs 77:7, pages 747-763.
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Sebastiano Mercadante & Russell K. Portenoy. (2016) Breakthrough cancer pain: twenty-five years of study. Pain 157:12, pages 2657-2663.
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R. Vellucci, G. Fanelli, R. Pannuti, C. Peruselli, S. Adamo, G. Alongi, F. Amato, L. Consoletti, L. Lamarca, S. Liguori, C. Lo Presti, A. Maione, S. Mameli, F. Marinangeli, S. Marulli, V. Minotti, D. Miotti, L. Montanari, G. Moruzzi, S. Palermo, M. Parolini, P. Poli, W. Tirelli, A. Valle & P. Romualdi. (2016) What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion. Drugs 76:3, pages 315-330.
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K. Ruberg & M. Thöns. 2016. Repetitorium Palliativmedizin. Repetitorium Palliativmedizin 283 311 .
Subramanian Pathmawathi, Tan Seng Beng, Lee Mei Li, Roshaslina Rosli, Supermanian Sharwend, Rasaiah R. Kavitha & Boey Chiong Meng Christopher. (2015) Satisfaction with and Perception of Pain Management among Palliative Patients with Breakthrough Pain: A Qualitative Study. Pain Management Nursing 16:4, pages 552-560.
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Antonio J. García Ruiz, José Luis Pérez Aguiar & Nuria García-Agua Soler. (2015) Gasto económico del tratamiento del dolor irruptivo. Medicina Paliativa 22, pages 62-70.
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Sebastiano Mercadante, Renato Vellucci, Arturo Cuomo, Claudio Adile, Andrea Cortegiani, Alessandro Valle, Patrizia Villari & Alessandra Casuccio. (2014) Long-term efficacy and tolerability of intranasal fentanyl in the treatment of breakthrough cancer pain. Supportive Care in Cancer 23:5, pages 1349-1354.
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Giovambattista Zeppetella, Andrew Davies, Indra Eijgelshoven & Jeroen P. Jansen. (2015) Une méta-analyse en réseau de l’efficacité des analgésiques opioïdes dans la prise en charge des épisodes d’accès douloureux paroxystiques d’origine cancéreuse. Douleurs : Evaluation - Diagnostic - Traitement 16:2, pages 61-76.
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Luis M Torres, Jose M Trinidad, Enrique Calderón, Diego Benitez & Michael Perelman. (2015) Fentanyl pectin nasal spray for breakthrough cancer pain. International Journal of Palliative Nursing 21:3, pages 114-116.
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Luis M. TorresJulia RevnicAlastair D. KnightMichael Perelman. (2014) Relationship between Onset of Pain Relief and Patient Satisfaction with Fentanyl Pectin Nasal Spray for Breakthrough Pain in Cancer. Journal of Palliative Medicine 17:10, pages 1150-1157.
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Paolo Bossi, Laura Locati, Cristiana Bergamini, Aurora Mirabile, Roberta Granata, Martina Imbimbo, Carlo Resteghini & Lisa Licitra. (2014) Fentanyl pectin nasal spray as treatment for incident predictable breakthrough pain (BTP) in oral mucositis induced by chemoradiotherapy in head and neck cancer. Oral Oncology 50:9, pages 884-887.
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Ravi Jandhyala, John R. Fullarton & Michael I. Bennett. (2014) Authors' Reply to Davis. Journal of Pain and Symptom Management 48:1, pages e3-e4.
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Furio Zucco, Cesare Bonezzi & Diego Fornasari. (2014) Breakthrough Cancer Pain (BTcP): a Synthesis of Taxonomy, Pathogenesis, Therapy, and Good Clinical Practice in Adult Patients in Italy. Advances in Therapy 31:7, pages 657-682.
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Willem J. Meijler. (2014) Reply: A Network Meta-analysis of the Efficacy of Opioid Analgesics for the Management of Breakthrough Cancer Pain Episodes. Journal of Pain and Symptom Management 47:6, pages e9-e10.
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Andrew N. Davies. (2014) Breakthrough Cancer Pain. Current Pain and Headache Reports 18:6.
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Giovambattista Zeppetella, Andrew Davies, Indra Eijgelshoven & Jeroen P. Jansen. (2014) A Network Meta-Analysis of the Efficacy of Opioid Analgesics for the Management of Breakthrough Cancer Pain Episodes. Journal of Pain and Symptom Management 47:4, pages 772-785.e5.
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Ravi Jandhyala, John R. Fullarton & Michael I. Bennett. (2013) Efficacy of Rapid-Onset Oral Fentanyl Formulations vs. Oral Morphine for Cancer-Related Breakthrough Pain: A Meta-Analysis of Comparative Trials. Journal of Pain and Symptom Management 46:4, pages 573-580.
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Michael S. Harlos, Simone Stenekes, David Lambert, Chris Hohl & Harvey Max Chochinov. (2013) Intranasal Fentanyl in the Palliative Care of Newborns and Infants. Journal of Pain and Symptom Management 46:2, pages 265-274.
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Helmar Bornemann-Cimenti, Mischa Wejbora, Istvan S. Szilagyi & Andreas Sandner-Kiesling. (2013) Fentanyl for the Treatment of Tumor-Related Breakthrough Pain. Deutsches Ärzteblatt international.
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Stanislas Grassin-DelyleEmmanuel Naline & Philippe Devillier. (2016) Comment: Intranasal Fentanyl Spray: A Novel Dosage Form for the Treatment of Breakthrough Cancer Pain. Annals of Pharmacotherapy 47:3, pages 427-428.
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K. Ruberg & M. Thöns. 2013. Repetitorium Palliativmedizin. Repetitorium Palliativmedizin 281 309 .
Eric Dietrich & John G Gums. (2012) Intranasal Fentanyl Spray: A Novel Dosage Form for the Treatment of Breakthrough Cancer Pain. Annals of Pharmacotherapy 46:10, pages 1382-1391.
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C.I. Ripamonti, D. Santini, E. Maranzano, M. Berti & F. Roila. (2012) Management of cancer pain: ESMO Clinical Practice Guidelines. Annals of Oncology 23, pages vii139-vii154.
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C.I. Ripamonti. (2012) Pain management. Annals of Oncology 23, pages x294-x301.
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Howard Smith. (2012) A Comprehensive Review of Rapid-Onset Opioids for Breakthrough Pain. CNS Drugs 26:6, pages 509-535.
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Claudia F. ClavijoRachael Rzasa LynnUwe ChristiansJeffrey L. Galinkin. (2012) Intranasal Fentanyl for Breakthrough Pain Control. Clinical Medicine Insights: Therapeutics 4, pages CMT.S7298.
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Frédéric Guirimand. (2011) Le fentanyl en soins palliatifs : de la pharmacologie à la clinique. Médecine Palliative : Soins de Support - Accompagnement - Éthique 10:6, pages 296-305.
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Sebastiano Mercadante. (2011) Emerging drugs for cancer-related pain. Supportive Care in Cancer 19:12, pages 1887-1893.
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Jeroen P. Jansen, Rachael Fleurence, Beth Devine, Robbin Itzler, Annabel Barrett, Neil Hawkins, Karen Lee, Cornelis Boersma, Lieven Annemans & Joseph C. Cappelleri. (2011) Interpreting Indirect Treatment Comparisons and Network Meta-Analysis for Health-Care Decision Making: Report of the ISPOR Task Force on Indirect Treatment Comparisons Good Research Practices: Part 1. Value in Health 14:4, pages 417-428.
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Bill Lord & Mae Deveson. (2011) Assessment and management of chronic pain in adults: implications for paramedics. Journal of Paramedic Practice 3:4, pages 166-172.
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Laurent Labreze, Louis Brasseur, Marilène Filbet, Patrick Ginies, Ivan Krakowski, Christian Minello, Philippe Poulain & Alain Serrie. (2011) Fentanyl intranasal : données cliniques dans le traitement des accès douloureux paroxystiques (ADP) en cancérologie. Douleurs : Evaluation - Diagnostic - Traitement 12:2, pages 65-71.
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. (2011) Current World Literature. Current Opinion in Supportive & Palliative Care 5:1, pages 65-68.
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Debby C.J. Vissers, Malin Lenre, Keith Tolley, Jan Jakobsson, Veronica Sendersky & Jeroen P. Jansen. (2011) An Economic Evaluation of Short-Acting Opioids for Treatment of Breakthrough Pain in Patients with Cancer. Value in Health 14:2, pages 274-281.
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Gérard E. Plante & Theodore B. VanItallie. (2010) Opioids for cancer pain: the challenge of optimizing treatment. Metabolism 59, pages S47-S52.
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