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Current Medical Research and Opinion Volume 26, 2010 - Issue 5
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Original Article

GOAL: multicenter, open-label, post-marketing study of flavocoxid, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin

Lakshmi Pillai Primus Pharmaceuticals, Inc., Scottsdale, AZ, USACorrespondence[email protected]
,
Bruce P. Burnett Primus Pharmaceuticals, Inc., Scottsdale, AZ, USA
,
Robert M. Levy Primus Pharmaceuticals, Inc., Scottsdale, AZ, USA
& for the GOAL Study Cooperative Group
Pages 1055-1063 | Accepted 11 Feb 2010, Published online: 15 Mar 2010

Citations (17)

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Read on this site (2)

Robert M Levy, Lakshmi Pillai & Bruce P Burnett. (2010) Nutritional benefits of flavocoxid in patients with osteoarthritis: efficacy and safety. Nutrition and Dietary Supplements 2, pages 27-38.
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Surrey M. Walton, Glen T. Schumock & David Andrew McLain. (2010) Cost analysis of flavocoxid compared to naproxen for management of mild to moderate OA. Current Medical Research and Opinion 26:9, pages 2253-2261.
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Articles from other publishers (15)

Siam-Yee Lee, Pooi-Fong Wong, Juliana Jamal & Margaret M. Roebuck. (2022) Naturally-derived endoplasmic reticulum stress inhibitors for osteoarthritis?. European Journal of Pharmacology 922, pages 174903.
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Donald J. AbrahamLiudmila L. Mazaleuskaya & Emanuela Ricciotti. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 54 .
Liudmila L. Mazaleuskaya & Emanuela Ricciotti. 2020. Druggable Lipid Signaling Pathways. Druggable Lipid Signaling Pathways 29 54 .
Xin Jin, Ming-Yan Liu, Dong-Fang Zhang, Xin Zhong, Ke Du, Ping Qian, Hua Gao & Min-Jie Wei. (2019) Natural products as a potential modulator of microglial polarization in neurodegenerative diseases. Pharmacological Research 145, pages 104253.
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Saleha Rehman, Bushra Nabi, Sanjula Baboota & Javed Ali. 2019. Discovery and Development of Anti-Inflammatory Agents from Natural Products. Discovery and Development of Anti-Inflammatory Agents from Natural Products 101 140 .
Teresa Pollicino, Cristina Musolino, Natasha Irrera, Alessandra Bitto, Daniele Lombardo, Martina Timmoneri, Letteria Minutoli, Giovanni Raimondo, Giovanni Squadrito, Francesco Squadrito & Domenica Altavilla. (2017) Flavocoxid exerts a potent antiviral effect against hepatitis B virus. Inflammation Research 67:1, pages 89-103.
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Catarina Pereira-Leite, Cláudia Nunes, Sarah K. Jamal, Iolanda M. Cuccovia & Salette Reis. (2017) Nonsteroidal Anti-Inflammatory Therapy: A Journey Toward Safety. Medicinal Research Reviews 37:4, pages 802-859.
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Simona Rossi & Victor J. Navarro. (2014) Herbs and Liver Injury: A Clinical Perspective. Clinical Gastroenterology and Hepatology 12:7, pages 1069-1076.
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Dhirendra Pratap Singh & Kanwaljit Chopra. (2014) Flavocoxid, dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, exhibits neuroprotection in rat model of ischaemic stroke. Pharmacology Biochemistry and Behavior 120, pages 33-42.
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Alessandra Bitto, Francesco Squadrito, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Anna Mecchio, Federica Galfo & Domenica Altavilla. (2014) Flavocoxid, a Nutraceutical Approach to Blunt Inflammatory Conditions. Mediators of Inflammation 2014, pages 1-8.
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D.M. Raditic & J.W. Bartges. 2014. Canine Rehabilitation and Physical Therapy. Canine Rehabilitation and Physical Therapy 254 276 .
Hector L. Lopez. (2012) Nutritional Interventions to Prevent and Treat Osteoarthritis. Part II: Focus on Micronutrients and Supportive Nutraceuticals. PM&R 4, pages S155-S168.
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Bruce P. Burnett & Robert M. Levy. (2012) 5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity. Advances in Therapy 29:2, pages 79-98.
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Bruce P. Burnett, Alessandra Bitto, Domenica Altavilla, Francesco Squadrito, Robert M. Levy & Lakshmi Pillai. (2011) Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), and 5-Lipoxygenase, Modifies COX-2 Gene Expression, and Acts as an Antioxidant. Mediators of Inflammation 2011, pages 1-11.
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Lakshmi Pillai, Robert M. Levy, Mesfin Yimam, Yuan Zhao, Qi Jia & Bruce P. Burnett. (2010) Flavocoxid, an anti-inflammatory agent of botanical origin, does not affect coagulation or interact with anticoagulation therapies. Advances in Therapy 27:6, pages 400-411.
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