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Non-clinical pharmacology, pharmacokinetics, and safety findings for the antihistamine bepotastine besilate

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Pages 2329-2338 | Accepted 15 Apr 2010, Published online: 25 Aug 2010

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Read on this site (6)

Megan E Cavet, Paul J Gomes, Warner W Carr & Jon I Williams. (2018) Bepotastine besilate ophthalmic solution 1.5% for alleviating nasal symptoms in patients with allergic conjunctivitis. Journal of Asthma and Allergy 11, pages 29-39.
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Ismael Carrillo-Martin, Alexei Gonzalez-Estrada & Ves Dimov. (2018) Bepotastine besilate for the treatment of perennial allergic rhinitis. Expert Opinion on Pharmacotherapy 19:15, pages 1727-1730.
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Duck Soo Lim, Yoo Seok Youn, Seung Jun Kwack, Hyo Min Kwak, Seong Kwang Lim, Ji Yun Kim, Yoon Mi Um, Jung Dae Lee, Ji Hyeon Hyeon, Yeon Joo Kim, Hyung Sik Kim & Byung-Mu Lee. (2014) Comparative Efficacy and Bioequivalence of Novel H1-Antihistamine Bepotastine Salts (Nicotinate and Salicylate). Journal of Toxicology and Environmental Health, Part A 77:22-24, pages 1451-1466.
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Leonard Bielory, Shubhasree Duttachoudhury & Andrea McMunn. (2013) Bepotastine besilate for the treatment of pruritus. Expert Opinion on Pharmacotherapy 14:18, pages 2553-2569.
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Kwan Hyung Cho & Han-Gon Choi. (2013) Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs. Drug Development and Industrial Pharmacy 39:6, pages 901-908.
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Gregg J Berdy & Heather S Oliff. (2010) Clinical safety and efficacy of bepotastine besilate ophthalmic solution to treat allergic conjunctivitis. Expert Review of Ophthalmology 5:5, pages 595-602.
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Articles from other publishers (11)

Sang-Won Jeon, Jin-Hyun Park, Joo-Eun Kim & Young-Joon Park. (2023) Design of experiment (DoE)-based formulation design of bepotastine sustained-release tablet and in vitro-in vivo pharmacokinetic correlation. Journal of Pharmaceutical Investigation 53:3, pages 407-416.
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Ji‐Hun Mo, Jin Hyeok Jeong, Tae Hoon Kim, Seon‐Tae Kim, Soo Whan Kim, Kun Hee Lee, Seung‐No Hong, Hyo Yeol Kim, Dae Woo Kim, Dong‐Young Kim, Chang‐Hoon Kim, Seok Hyun Cho & Chae‐Seo Rhee. (2020) Double‐Blind Placebo‐Controlled Trial of Bepotastine Salicylate in Patients With Allergic Rhinitis. The Laryngoscope 131:3.
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Amrita Sil, Sufiur Rahaman, Nasiruddin Mondal, SkShahriar Ahmed, Dhiman Tarafdar, ApareshChandra Patra, Sudipta Roy & NilayKanti Das. (2021) An investigator-blind randomized controlled trial comparing effectiveness, safety of levocetirizine and bepotastine in chronic urticaria. Indian Journal of Dermatology 66:5, pages 472.
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Ju Wan KangJaechun Lee. (2016) Bepotastine-induced urticaria, cross-reactive with other antihistamines. Asia Pacific Allergy 6:4, pages 253.
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Y. K. Choi, Y. H. Chung, Y. S. Nam, D. Y. Kang, H. Kim, S. E. Lee, H. R. Kim, Y. S. Lee & J. H. Jeong. (2013) UPLC-MS/MS Method for Determination of Bepotastine in Human Plasma. Journal of Chromatographic Science 52:8, pages 886-893.
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Garry M. Walsh. 2014. A worldwide yearly survey of new data in adverse drug reactions and interactions. A worldwide yearly survey of new data in adverse drug reactions and interactions 295 307 .
Kyoung-Ah Kim & Ji-Young Park. (2013) Pharmacokinetic Comparisons of Bepotastine Besilate and Bepotastine Salicylate in Healthy Subjects. Clinical Drug Investigation 33:12, pages 913-919.
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Eric Y Chen, Maria Garnica, Yung-Chen Wang, Alexander J Mintz, Chi-Shuo Chen & Wei-Chun Chin. (2012) A mixture of anatase and rutile TiO2 nanoparticles induces histamine secretion in mast cells. Particle and Fibre Toxicology 9:1.
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Tamihiro KAWAKAMI, Satoko KIMURA, Tsuneo HAGA, Risako DOI, Mikiko KYOYA, Keiko NAKAGAWA & Yoshinao SOMA. (2011) Health‐related quality of life assessed by the effect of bepotastine besilate in patients with pruritus: Importance of emotions score in atopic dermatitis. The Journal of Dermatology 39:6, pages 527-530.
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Yao Meng, Bin Liu, Ning Lei, Juecun Zheng, Qianchuan He, Dan Li, Xiaojun Zhao & Fubing Shen. (2012) Alpha-momorcharin possessing high immunogenicity, immunotoxicity and hepatotoxicity in SD rats. Journal of Ethnopharmacology 139:2, pages 590-598.
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. (2011) Current World Literature. Current Opinion in Allergy & Clinical Immunology 11:6, pages 594-598.
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