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Original Article

Efficacy and safety of oxycodone HCl/niacin tablets for the treatment of moderate-to-severe postoperative pain following bunionectomy surgery

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Pages 593-603 | Accepted 13 Dec 2010, Published online: 13 Jan 2011

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Read on this site (7)

Ira J Gottlieb, Deborah R Tunick, Randall J Mack, Stewart W McCallum, Campbell P Howard, Alex Freyer & Wei Du. (2018) Evaluation of the safety and efficacy of an intravenous nanocrystal formulation of meloxicam in the management of moderate-to-severe pain after bunionectomy. Journal of Pain Research 11, pages 383-393.
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Neil Singla, Rachel Margulis, Kenneth Kostenbader, Yanping Zheng, Thomas Barrett, Michael J. Giuliani, Yin Chen & Jim L. Young. (2015) Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain. The Physician and Sportsmedicine 43:2, pages 126-137.
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Neil Singla, Thomas Barrett, Lisa Sisk, Kenneth Kostenbader & Jim Young. (2014) Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery. Current Medical Research and Opinion 30:12, pages 2571-2578.
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Neil Singla, Thomas Barrett, Lisa Sisk, Kenneth Kostenbader, Jim Young & Michael Giuliani. (2014) A randomized, double-blind, placebo-controlled study of the efficacy and safety of MNK-795, a dual-layer, biphasic, immediate-release and extended-release combination analgesic for acute pain. Current Medical Research and Opinion 30:3, pages 349-359.
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Mellar Davis, Harold W Goforth & Pam Gamier. (2013) Oxycodone combined with opioid receptor antagonists: efficacy and safety. Expert Opinion on Drug Safety 12:3, pages 389-402.
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Laura M Lourenço, Michele Matthews & Robert N Jamison. (2013) Abuse-deterrent and tamper-resistant opioids: how valuable are novel formulations in thwarting non-medical use?. Expert Opinion on Drug Delivery 10:2, pages 229-240.
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Articles from other publishers (11)

Lorenzo Franco-de la Torre, Eduardo Gómez-Sánchez, Othoniel Hugo Aragon-Martinez, Adriana Hernández-Gómez, Diana Laura Franco-González, Juan Manuel Guzmán-Flores, Angel Josabad Alonso-Castro, Vinicio Granados-Soto & Mario Alberto Isiordia-Espinoza. (2023) Analgesic Efficacy and Safety of Tapentadol Immediate Release in Bunionectomy: A Meta-Analysis. Pharmaceuticals 16:9, pages 1287.
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Neil K. Singla, Diana S. Meske & Paul J. Desjardins. (2017) Exploring the Interplay between Rescue Drugs, Data Imputation, and Study Outcomes: Conceptual Review and Qualitative Analysis of an Acute Pain Data Set. Pain and Therapy 6:2, pages 165-175.
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Thomas BarrettKenneth KostenbaderSrinivas NalamachuMichael GiulianiJim L. Young. (2015) Safety and Tolerability of Biphasic Immediate‐Release/Extended‐Release Oxycodone/Acetaminophen Tablets: Analysis of 11 Clinical Trials. Pain Practice 16:7, pages 856-868.
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Eugene R. Viscusi, Lynn Webster, Michael Kuss, Stephen Daniels, James A. Bolognese, Seth Zuckerman, David G. Soergel, Ruth Ann Subach, Emily Cook & Franck Skobieranda. (2016) A randomized, phase 2 study investigating TRV130, a biased ligand of the μ-opioid receptor, for the intravenous treatment of acute pain. Pain 157:1, pages 264-272.
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Neil Singla, Matthew Hunsinger, Phoebe D. Chang, Michael P. McDermott, Amit K. Chowdhry, Paul J. Desjardins, Dennis C. Turk & Robert H. Dworkin. (2015) Assay Sensitivity of Pain Intensity Versus Pain Relief in Acute Pain Clinical Trials: ACTTION Systematic Review and Meta-Analysis. The Journal of Pain 16:8, pages 683-691.
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Mark T. Leibowitz, Cynthia A. Zamora, Albert W. Brzeczko & Jeffrey G. Stark. (2014) A Single-Dose, 3-Way Crossover Pharmacokinetic Comparison Between Immediate-Release Oxycodone Hydrochloride With Aversion Technology (IRO-A, Oxecta), IRO-A With Niacin, and Oxycodone Hydrochloride (Roxicodone) in Healthy Adults Under Fasting Conditions. American Journal of Therapeutics 21:2, pages 99-105.
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Neil K. Singla, Paul J. Desjardins & Phoebe D. Chang. (2014) A comparison of the clinical and experimental characteristics of four acute surgical pain models: Dental extraction, bunionectomy, joint replacement, and soft tissue surgery. Pain 155:3, pages 441-456.
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Edward Michna, Wendy Y. Cheng, Caroline Korves, Howard Birnbaum, Ryan Andrews, Zhou Zhou, Ashish V. Joshi, David Schaaf, Jack Mardekian & Mei Sheng. (2014) Systematic Literature Review and Meta-Analysis of the Efficacy and Safety of Prescription Opioids, Including Abuse-Deterrent Formulations, in Non-Cancer Pain Management. Pain Medicine 15:1, pages 79-92.
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Bernard Bannwarth. (2012) Will Abuse-Deterrent Formulations of Opioid Analgesics Be Successful in Achieving Their Purpose?. Drugs 72:13, pages 1713-1723.
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Steven P. Stanos, Patricia Bruckenthal & Robert L. Barkin. (2012) Strategies to Reduce the Tampering and Subsequent Abuse of Long-acting Opioids: Potential Risks and Benefits of Formulations With Physical or Pharmacologic Deterrents to Tampering. Mayo Clinic Proceedings 87:7, pages 683-694.
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Michael Golf, Stephen E. Daniels & Erol Onel. (2011) A phase 3, randomized, placebo-controlled trial of DepoFoam® bupivacaine (extended-release bupivacaine local analgesic) in bunionectomy. Advances in Therapy 28:9, pages 776-788.
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