3,339
Views
51
CrossRef citations to date
0
Altmetric
Review

Mechanisms of pain transmission and pharmacologic management

Pages 2019-2031 | Accepted 12 Aug 2011, Published online: 14 Sep 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Mengkang Gao, Yusui Wang, Lanqi Liu, Zhenrui Qiao & Lin Yan. (2021) A patent review of transient receptor potential vanilloid type 1 modulators (2014–present). Expert Opinion on Therapeutic Patents 31:2, pages 169-187.
Read now
Carmela Parenti, Giuseppina Aricò, Marzio Pennisi, Alessandro Venditti & Giovanna M. Scoto. (2016) Harpagophytum procumbens extract potentiates morphine antinociception in neuropathic rats. Natural Product Research 30:11, pages 1248-1255.
Read now
Ahmet Ayar, Mete Ozcan, Kemal Tuğrul Kuzgun & Omer Faruk Kalkan. (2015) Spinorphin inhibits membrane depolarization- and capsaicin-induced intracellular calcium signals in rat primary nociceptive dorsal root ganglion neurons in culture. Journal of Receptors and Signal Transduction 35:6, pages 550-558.
Read now
Elisa Mura, Stefano Govoni, Marco Racchi, Valeria Carossa, Guglielmina Nadia Ranzani, Massimo Allegri & Ron HN van Schaik. (2013) Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?. Journal of Pain Research 6, pages 331-353.
Read now

Articles from other publishers (47)

Ali Mohammad Pourbagher‐Shahri & Fatemeh Forouzanfar. (2023) Saffron ( Crocus sativus ) and its constituents for pain management: A review of current evidence . Phytotherapy Research 37:11, pages 5041-5057.
Crossref
V.O. Telegan & K.V. Tarasenko. (2023) PECULIARITIES OF POSTOPERATIVE PAIN IN THE ELDERLY AND SENILE PATIENTS AT DIFFERENT STAGES OF NOCICEPTION. The Medical and Ecological Problems 27:3-4, pages 21-25.
Crossref
Naveed Muhammad, Ihtesham Ul Haq, Muhammad Saeed Jan, Taghrid S. AlOmar, Abdur Rauf, Abdul Wadood, Najla Almasoud & Sulaiman Shams. (2023) In-vitro and in-vivo assessment of the anti-diabetic, analgesic, and anti-inflammatory potenstials of metal-based carboxylates derivative. Heliyon 9:8, pages e19160.
Crossref
Nivedita Bhardwaj, Nancy Tripathi, Ram A. Vishwakarma & Shreyans K. Jain. 2023. Natural Products. Natural Products 133 162 .
Cheng-Yu Shentu, Ge Yan, Dong-Chen Xu, Yong Chen & Li-Hua Peng. (2022) Emerging pharmaceutical therapeutics and delivery technologies for osteoarthritis therapy. Frontiers in Pharmacology 13.
Crossref
Nazlı TURAN, Umut İrfan ÜÇEL, Cevşen YAZICI, Ümide DEMİR ÖZKAY & Özgür Devrim CAN. (2022) OPIOIDERGIC SYSTEM-MEDIATED ANTINOCICEPTIVE ACTIVITY OF TOFISOPAM. Ankara Universitesi Eczacilik Fakultesi Dergisi, pages 712-727.
Crossref
Maria Kouri, Martina Rekatsina, Athina Vadalouca, Ioanna Siafaka, Emmanouil Vardas, Erofili Papadopoulou, Antonella Paladini & Giustino Varrassi. (2022) Pharmacological Management of Neuropathic Pain after Radiotherapy in Head and Neck Cancer Patients: A Systematic Review. Journal of Clinical Medicine 11:16, pages 4877.
Crossref
Hugo F. Miranda, Viviana Noriega, Fernando Sierralta, Ramón Sotomayor‐Zárate & Juan Carlos Prieto. (2022) Risperidone in analgesia induced by paracetamol and meloxicam in experimental pain. Fundamental & Clinical Pharmacology 36:3, pages 494-500.
Crossref
Hideki Shimomura. (2022) Emotional Problems in Pediatric Headache Patients. Current Pain and Headache Reports 26:6, pages 469-474.
Crossref
Menglan Wang & Baskaran Thyagarajan. (2020) Pain pathways and potential new targets for pain relief. Biotechnology and Applied Biochemistry 69:1, pages 110-123.
Crossref
Lorella Pasquinucci, Carmela Parenti, Zafiroula Georgoussi, Lorena Reina, Emilia Tomarchio & Rita Turnaturi. (2021) LP1 and LP2: Dual-Target MOPr/DOPr Ligands as Drug Candidates for Persistent Pain Relief. Molecules 26:14, pages 4168.
Crossref
Karina Genaro & Wiliam A. Prado. (2021) The role of the anterior pretectal nucleus in pain modulation: A comprehensive review. European Journal of Neuroscience 54:1, pages 4358-4380.
Crossref
Nazlı Turan Yücel, Derya Osmaniye, Ümmühan Kandemir, Asaf Evrim Evren, Özgür Devrim Can & Ümide Demir Özkay. (2021) Synthesis and Antinociceptive Effect of Some Thiazole-Piperazine Derivatives: Involvement of Opioidergic System in the Activity. Molecules 26:11, pages 3350.
Crossref
Nazlı Turan Yücel, Ümmühan Kandemir, Ümide Demir Özkay & Özgür Devrim Can. (2021) 5-HT1A Serotonergic, α-Adrenergic and Opioidergic Receptors Mediate the Analgesic Efficacy of Vortioxetine in Mice. Molecules 26:11, pages 3242.
Crossref
Cesar Margarit Ferri, Silvia Natoli, Paz Sanz-Ayan, Alberto Magni, Carlos Guerrero, Argelia Lara-Solares, Hiltrud Liedgens, Guido Thömmes & Ravi Karra. (2021) Quality of life and functional outcomes with tapentadol prolonged release in chronic musculoskeletal pain: post hoc analysis . Pain Management 11:2, pages 173-187.
Crossref
V Noriega, F Sierralta, P Poblete, N Aranda, R Sotomayor-Zárate, J C Prieto & H F Miranda. (2020) Receptors involved in dexketoprofen analgesia in murine visceral pain. Journal of Biosciences 45:1.
Crossref
Vidya Chidambaran, Maria Ashton, Lisa J. Martin & Anil G. Jegga. (2020) Systems biology-based approaches to summarize and identify novel genes and pathways associated with acute and chronic postsurgical pain. Journal of Clinical Anesthesia 62, pages 109738.
Crossref
Moon-Jong Kim & Hong-Seop Kho. (2019) Treatment Outcomes of Venlafaxine and Duloxetine in Refractory Burning Mouth Syndrome Patients. Journal of Oral Medicine and Pain 44:3, pages 83-91.
Crossref
Linda C. Cole. (2018) Psychosocial Issues and Lifestyle Changes for the Renal Patient. Nursing Clinics of North America 53:4, pages 589-600.
Crossref
Ellison Neves de Lima, Ana Rosa Brissant de Andrade, Leila Bastos Leal & Davi Pereira de Santana. (2018) Levobupivacaine Thermogel for Long-acting Analgesia. AAPS PharmSciTech 19:6, pages 2533-2542.
Crossref
Anitha MuddanaDiane T. AsbillMaya R. JerathAlison M. Stuebe. (2018) Quantitative Sensory Testing, Antihistamines, and Beta-Blockers for Management of Persistent Breast Pain: A Case Series. Breastfeeding Medicine 13:4, pages 275-280.
Crossref
Kinga Sałat, Anna Furgała & Robert Sałat. (2017) Evaluation of cebranopadol, a dually acting nociceptin/orphanin FQ and opioid receptor agonist in mouse models of acute, tonic, and chemotherapy-induced neuropathic pain. Inflammopharmacology 26:2, pages 361-374.
Crossref
Hamid Ghasemi, Esmaeal Tamaddonfard & Farhad Soltanalinejad. (2017) Role of thalamic ventral posterolateral nucleus histamine H 2 and opiate receptors in modulation of formalin-induced muscle pain in rats. Pharmacological Reports 69:6, pages 1393-1401.
Crossref
Misty D. Smith, Jose H. Woodhead, Laura J. Handy, Timothy H. Pruess, Fabiola Vanegas, Erin Grussendorf, Joel Grussendorf, Karen White, Karolina K. Bulaj, Reisa K. Krumin, Megan Hunt & Karen S. Wilcox. (2017) Preclinical Comparison of Mechanistically Different Antiseizure, Antinociceptive, and/or Antidepressant Drugs in a Battery of Rodent Models of Nociceptive and Neuropathic Pain. Neurochemical Research 42:7, pages 1995-2010.
Crossref
Brian Lockhart & R. Jason Yong. 2017. Pain Medicine. Pain Medicine 147 148 .
Merve Kasap & Özgür Devrim Can. (2016) Opioid system mediated anti-nociceptive effect of agomelatine in mice. Life Sciences 163, pages 55-63.
Crossref
Joseph V. PergolizziJrJr, Robert B. Raffa, Gianpietro Zampogna, Frank Breve, Robert Colucci, William K. Schmidt & Jo Ann LeQuang. (2016) Comments and Suggestions from Pain Specialists Regarding the CDC 's Proposed Opioid Guidelines . Pain Practice 16:7, pages 794-808.
Crossref
Mehlika Altıntop, Özgür Can, Ümide Demir Özkay & Zafer Kaplancıklı. (2016) Synthesis and Evaluation of New 1,3,4-Thiadiazole Derivatives as Antinociceptive Agents. Molecules 21:8, pages 1004.
Crossref
Wael Saasouh, Nelroy Jones, Taylor Stang, Karen Hovsepyan, Christine Chang & Alparslan Turan. (2016) Effect of intravenous acetaminophen on post-operative opioid-related complications: study protocol for a randomized, placebo-controlled trial. Asia Pacific Journal of Clinical Trials: Nervous System Diseases 1:4, pages 154.
Crossref
Rita Turnaturi, Giuseppina Aricò, Giuseppe Ronsisvalle, Carmela Parenti & Lorella Pasquinucci. (2016) Multitarget opioid ligands in pain relief: New players in an old game. European Journal of Medicinal Chemistry 108, pages 211-228.
Crossref
Jo NijsJo Nijs. 2016. Centrale sensitisatiepijn in de klinische praktijk. Centrale sensitisatiepijn in de klinische praktijk 75 119 .
José Sarmento-Neto, Lázaro do Nascimento, Cícero Felipe & Damião de Sousa. (2015) Analgesic Potential of Essential Oils. Molecules 21:1, pages 20.
Crossref
Cui-Jie Shao, Yong Gao, Li Zhao, Dan Jin, Dan Wang & De-Qiang Wang. (2015) Co-application of lidocaine and QX-572 induces divergent pain behaviours in mice. Journal of Pharmacy and Pharmacology 67:9, pages 1272-1278.
Crossref
William W. MuirIIIIII. 2015. Handbook of Veterinary Pain Management. Handbook of Veterinary Pain Management 335 355 .
William W. MuirIIIIII. 2015. Handbook of Veterinary Pain Management. Handbook of Veterinary Pain Management 113 141 .
Mikwang Kwon, Murat Altin, Hector Duenas & Levent Alev. (2014) The Role of Descending Inhibitory Pathways on Chronic Pain Modulation and Clinical Implications. Pain Practice 14:7, pages 656-667.
Crossref
Grisell Vargas-Schaffer. (2014) Drugs able to prevent chronic pain. Techniques in Regional Anesthesia and Pain Management 18:3, pages 92-99.
Crossref
Viviana Noriega, Fernando Sierralta, Juan Carlos Prieto, Pilar Zanetta & Hugo F. Miranda. (2014) Nitridergic Modulation of the Antinociceptive Activity of Rosuvastatin in Mice. Pharmacology & Pharmacy 05:01, pages 61-68.
Crossref
Karen L. Machin. 2013. Pain Management in Veterinary Practice. Pain Management in Veterinary Practice 407 415 .
V. M. Kushnir, B. Cassell, C. P. Gyawali, R. D. Newberry, P. Kibe, B. D. Nix, A. Sabzpoushan, N. D. Kanuri & G. S. Sayuk. (2013) Genetic variation in the beta-2 adrenergic receptor (ADRB2) predicts functional gastrointestinal diagnoses and poorer health-related quality of life. Alimentary Pharmacology & Therapeutics 38:3, pages 313-323.
Crossref
Ümide Demir Özkay & Özgür Devrim Can. (2013) Anti-nociceptive effect of vitexin mediated by the opioid system in mice. Pharmacology Biochemistry and Behavior 109, pages 23-30.
Crossref
Carmela Parenti, Rita Turnaturi, Giuseppina Aric?Alexandra Gramowski-Vo?Olaf H.-U. Schroeder, Agostino Marrazzo, Orazio Prezzavento, Simone Ronsisvalle, Giovanna M. Scoto, Giuseppe Ronsisvalle & Lorella Pasquinucci. (2013) The multitarget opioid ligand LP1's effects in persistent pain and in primary cell neuronal cultures. Neuropharmacology 71, pages 70-82.
Crossref
L. I. G. Paula‐Freire, M. L. Andersen, G. R. Molska, D. O. Köhn & E. L. A. Carlini. (2012) Evaluation of the Antinociceptive Activity of Ocimum gratissimum L. (Lamiaceae) Essential Oil and its isolated Active Principles in Mice . Phytotherapy Research 27:8, pages 1220-1224.
Crossref
Patrick H. Finan & Michael T. Smith. (2013) The comorbidity of insomnia, chronic pain, and depression: Dopamine as a putative mechanism. Sleep Medicine Reviews 17:3, pages 173-183.
Crossref
Martin Houde, Walid Semaan, Giles Rae & Pedro D’Orléans-Juste. (2012) GPCR models of pain in cardiovascular diseases: Contributions of kinins and endothelins. Drug Discovery Today: Disease Models 9:3, pages e137-e142.
Crossref
Yvonne D'Arcy. (2012) Treating Acute Pain in the Hospitalized Patient. The Nurse Practitioner 37:8, pages 22-30.
Crossref
Carmela Parenti, Rita Turnaturi, Giuseppina Aric?Agostino Marrazzo, Orazio Prezzavento, Simone Ronsisvalle, Giovanna M. Scoto, Giuseppe Ronsisvalle & Lorella Pasquinucci. (2012) Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand. Life Sciences 90:25-26, pages 957-961.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.