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Respiratory Medicine: Review

Challenges with current inhaled treatments for chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis

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Pages 1059-1067 | Accepted 07 Mar 2012, Published online: 10 May 2012

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Tiffanie Daisy Sugianto & Hak-Kim Chan. (2016) Inhaled antibiotics in the treatment of non-cystic fibrosis bronchiectasis: clinical and drug delivery perspectives. Expert Opinion on Drug Delivery 13:1, pages 7-22.
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Marta Garcia-Clemente, David de la Rosa, Luis Máiz, Rosa Girón, Marina Blanco, Casilda Olveira, Rafael Canton & Miguel Angel Martinez-García. (2020) Impact of Pseudomonas aeruginosa Infection on Patients with Chronic Inflammatory Airway Diseases. Journal of Clinical Medicine 9:12, pages 3800.
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Éanna Forde, Graeme Kelly, Louise Sweeney, Deirdre Fitzgerald-Hughes, Ronan MacLoughlin & Marc Devocelle. (2019) Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis. Pharmaceutics 11:5, pages 239.
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Éanna Forde, André Schütte, Emer Reeves, Catherine Greene, Hilary Humphreys, Marcus Mall, Deirdre Fitzgerald-Hughes & Marc Devocelle. (2016) Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis . Antimicrobial Agents and Chemotherapy 60:5, pages 2813-2821.
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Ivana d’Angelo, Bruno Casciaro, Agnese Miro, Fabiana Quaglia, Maria Luisa Mangoni & Francesca Ungaro. (2015) Overcoming barriers in Pseudomonas aeruginosa lung infections: Engineered nanoparticles for local delivery of a cationic antimicrobial peptide. Colloids and Surfaces B: Biointerfaces 135, pages 717-725.
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Ana Margarida Sousa, Maria Olívia Pereira & Anália Lourenço. (2015) MorphoCol: An ontology-based knowledgebase for the characterisation of clinically significant bacterial colony morphologies. Journal of Biomedical Informatics 55, pages 55-63.
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Eanna Forde & Marc Devocelle. (2015) Pro-Moieties of Antimicrobial Peptide Prodrugs. Molecules 20:1, pages 1210-1227.
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Ivana d'Angelo, Claudia Conte, Maria Immacolata La Rotonda, Agnese Miro, Fabiana Quaglia & Francesca Ungaro. (2014) Improving the efficacy of inhaled drugs in cystic fibrosis: Challenges and emerging drug delivery strategies. Advanced Drug Delivery Reviews 75, pages 92-111.
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Éanna Forde, Hilary Humphreys, Catherine M. Greene, Deirdre Fitzgerald-Hughes & Marc Devocelle. (2014) Potential of Host Defense Peptide Prodrugs as Neutrophil Elastase-Dependent Anti-Infective Agents for Cystic Fibrosis. Antimicrobial Agents and Chemotherapy 58:2, pages 978-985.
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M. Hoppentocht, P. Hagedoorn, H.W. Frijlink & A.H. de Boer. (2014) Developments and strategies for inhaled antibiotic drugs in tuberculosis therapy: A critical evaluation. European Journal of Pharmaceutics and Biopharmaceutics 86:1, pages 23-30.
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David CipollaHak-Kim Chan. (2013) Inhaled antibiotics to treat lung infection. Pharmaceutical Patent Analyst 2:5, pages 647-663.
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