1,537
Views
52
CrossRef citations to date
0
Altmetric
Diabetes: Original Article

Adherence patterns in patients with type 2 diabetes on basal insulin analogues: missed, mistimed and reduced doses

, &
Pages 1933-1946 | Received 21 Sep 2012, Published online: 14 Nov 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Tracy J Sims, Kristina S Boye, Susan Robinson & Tessa Kennedy-Martin. (2022) Treatment-Related Attributes of Diabetes Therapies and How People with Type 2 Diabetes Report Their Impact on Indicators of Medication-Taking Behaviors. Patient Preference and Adherence 16, pages 1919-1939.
Read now
Nick Freemantle, Didac Mauricio, Andrea Giaccari, Timothy Bailey, Ronan Roussel, Denise Franco, Baptiste Berthou, Valerie Pilorget, Jukka Westerbacka, Zsolt Bosnyak, Mireille Bonnemaire, Anna M. G. Cali, My-Liên Nguyên-Pascal, Alfred Penfornis, Manuel Perez-Maraver, Jochen Seufert, Sean D. Sullivan, John Wilding, Carol Wysham & Melanie Davies. (2020) Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus. Current Medical Research and Opinion 36:4, pages 571-581.
Read now
Hilton Kaplan, Aslam Amod, Francois H van Zyl, Jeevren Reddy, Alet van Tonder, Ellina Tsymbal & Alicia McMaster. (2019) Incidence of hypoglycaemia in the South African population with diabetes: results from the IDMPS Wave 7 study. Journal of Endocrinology, Metabolism and Diabetes of South Africa 24:2, pages 58-64.
Read now
Hiroyuki Ito, Emiko Tsugami, Shigenori Ando, Rie Araki, Suzuko Matsumoto, Kosuke Uemura, Shinya Nishio, Shinichi Antoku, Tomoko Yamasaki, Toshiko Mori & Michiko Togane. (2018) A comparison of the clinical courses of type 2 diabetic patients whose basal insulin preparation was replaced from insulin glargine 100 units/mL to insulin glargine biosimilar or 300 units/mL: a propensity score-matched observation study. Journal of Drug Assessment 7:1, pages 54-60.
Read now
Wing Bun Chan, Jung Fu Chen, Su-Yen Goh, Thi Thanh Huyen Vu, Iris Thiele Isip-Tan, Sony Wibisono Mudjanarko, Shailendra Bajpai, Maria Aileen Mabunay & Pongamorn Bunnag. (2017) Challenges and unmet needs in basal insulin therapy: lessons from the Asian experience. Diabetes, Metabolic Syndrome and Obesity 10, pages 521-532.
Read now
Jan BroŽ, Denisa Janickova Zdarska, Jana Urbanova, Marek Brabec, Bohumila Krivska, Viera Donicova, Radka Stepanova, Emil Martinka & Milan Kvapil. (2016) An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey. Open Access Journal of Clinical Trials 8, pages 13-20.
Read now
Frank Lavernia, Pamela Kushner, Dace Trence, Donna Rice, George Dailey & Louis Kuritzky. (2015) Recognizing and minimizing hypoglycemia: The need for individualized care. Postgraduate Medicine 127:8, pages 801-807.
Read now
Meryl Brod, Kathryn M Pfeiffer, Kasper Mandel Clausen, Rasmus Skovgaard & Jens Harald Kongsø. (2014) Insulin-taking behavior and memory problems among people with diabetes in five countries: findings from a web survey. Patient Intelligence 6, pages 43-60.
Read now
Sarah Clifford, Magaly Perez-Nieves, Anne M. Skalicky, Matthew Reaney & Karin S. Coyne. (2014) A systematic literature review of methodologies used to assess medication adherence in patients with diabetes. Current Medical Research and Opinion 30:6, pages 1071-1085.
Read now

Articles from other publishers (43)

Jannie Toft Damsgaard Nørlev, Ole Hejlesen, Morten Hasselstrøm Jensen & Stine Hangaard. (2023) Quantification of insulin adherence in adults with insulin-treated type 2 diabetes: A systematic review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 17:12, pages 102908.
Crossref
Mark T. Marston, Lut Berben, Fabienne Dobbels, Cynthia L. Russell & Sabina de Geest. (2023) Prevalence and Patient-Level Correlates of Intentional Non-Adherence to Immunosuppressive Medication After Heart-Transplantation—Findings From the International BRIGHT Study. Transplant International 36.
Crossref
Bruno Guerci. (2023) Quelle place de la diabétologie connectée pour les patients en multi-injections d'insuline ?. Médecine des Maladies Métaboliques 17:2, pages 2S11-2S21.
Crossref
Rodolfo J. Galindo, Clementina Ramos, Saumeth Cardona, Priyathama Vellanki, Georgia M. Davis, Omolade Oladejo, Bonnie Albury, Neil Dhruv, Limin Peng & Guillermo E. Umpierrez. (2021) Efficacy of a Smart Insulin Pen Cap for the Management of Patients with Uncontrolled Type 2 Diabetes: A Randomized Cross-Over Trial. Journal of Diabetes Science and Technology 17:1, pages 201-207.
Crossref
V. V. Klimontov. (2022) Predictors of success and failure in achieving glycemic control targets in patients with type 2 diabetes on basal insulin: review of the real-world evidence studies. Diabetes mellitus 25:6, pages 556-563.
Crossref
Neda Rajamand Ekberg, Niels Væver Hartvig, Anne Kaas, Jonas Bech Møller & Peter Adolfsson. (2022) Smart Pen Exposes Missed Basal Insulin Injections and Reveals the Impact on Glycemic Control in Adults With Type 1 Diabetes. Journal of Diabetes Science and Technology, pages 193229682211041.
Crossref
Siew Yee Yong, Greta Miranda Goh & Huai Heng Loh. (2020) Insulin adherence and the associated factors among patients with type 2 diabetes mellitus at the Hospital Queen Elizabeth II, Sabah. Journal of Public Health 30:5, pages 1319-1327.
Crossref
Susan RobinsonRachel S. Newson, Birong LiaoTessa Kennedy-MartinTadej Battelino. (2021) Missed and Mistimed Insulin Doses in People with Diabetes: A Systematic Literature Review. Diabetes Technology & Therapeutics 23:12, pages 844-856.
Crossref
Philip Levin, Byron J. Hoogwerf, Janet Snell-Bergeon, Tim Vigers, Laura Pyle & Lee Bromberger. (2021) Ultra Rapid-Acting Inhaled Insulin Improves Glucose Control in Patients With Type 2 Diabetes Mellitus. Endocrine Practice 27:5, pages 449-454.
Crossref
Elena Toschi & Medha N. Munshi. (2020) Benefits and Challenges of Diabetes Technology Use in Older Adults. Endocrinology and Metabolism Clinics of North America 49:1, pages 57-67.
Crossref
Antonio Ceriello, Harold W. deValk, Bruno Guerci, Thomas Haak, David Owens, Michela Canobbio, Katharina Fritzen, Constantin Stautner & Oliver Schnell. (2020) The burden of type 2 diabetes in Europe: Current and future aspects of insulin treatment from patient and healthcare spending perspectives. Diabetes Research and Clinical Practice 161, pages 108053.
Crossref
Sanjay Kalra, Sarita Bajaj, Surendra Kumar Sharma, Gagan Priya, Manash P. Baruah, Debmalya Sanyal, Sambit Das, Tirthankar Chaudhury, Kalyan Kumar Gangopadhyay, Ashok Kumar Das, Bipin Sethi, Vageesh Ayyar, Shehla Shaikh, Parag Shah, Sushil Jindal, Vaishali Deshmukh, Joel Dave, Aslam Amod, Ansumali Joshi, Sunil Pokharel, Faruque Pathan, Faria Afsana, Indrajit Prasad, Moosa Murad, Soebagijo Adi Soelistijo, Johanes Purwoto, Zanariah Hussein, Lee Chung Horn, Rakesh Sahay, Noel Somasundaram, Charles Antonypillai, Manilka Sumanathilaka & Uditha Bulugahapitiya. (2020) A Practitioner’s Toolkit for Insulin Motivation in Adults with Type 1 and Type 2 Diabetes Mellitus: Evidence-Based Recommendations from an International Expert Panel. Diabetes Therapy 11:3, pages 585-606.
Crossref
Lisa R. Volpatti, Morgan A. Matranga, Abel B. Cortinas, Derfogail Delcassian, Kevin B. Daniel, Robert Langer & Daniel G. Anderson. (2019) Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery. ACS Nano 14:1, pages 488-497.
Crossref
Mark Warren & Donna Steel. (2020) Clinical Use of IDegLira: Initiation to Titration After Basal Insulin. Clinical Diabetes 38:1, pages 62-70.
Crossref
Luigi F. Meneghini, Didac Mauricio, Emanuela Orsi, Nebojsa M. Lalic, Anna M.G. Cali, Jukka Westerbacka, Peter Stella, Christophe Candelas, DEA, Valerie Pilorget, Riccardo Perfetti & Kamlesh Khunti. (2019) The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real‐world setting. Diabetes, Obesity and Metabolism 21:6, pages 1429-1436.
Crossref
Fernando Gomez-PeraltaCristina AbreuSara Gomez-RodriguezLuis Ruiz. (2019) Insulclock : A Novel Insulin Delivery Optimization and Tracking System . Diabetes Technology & Therapeutics 21:4, pages 209-214.
Crossref
Bruno Guerci, Neha Chanan, Simarjeet Kaur, Juan Guillermo Jasso-Mosqueda & Elisheva Lew. (2019) Lack of Treatment Persistence and Treatment Nonadherence as Barriers to Glycaemic Control in Patients with Type 2 Diabetes. Diabetes Therapy 10:2, pages 437-449.
Crossref
Kathy Ellis, Henrietta Mulnier & Angus Forbes. (2018) Perceptions of insulin use in type 2 diabetes in primary care: a thematic synthesis. BMC Family Practice 19:1.
Crossref
Jo Satoh, Marc Andersen, Brian Bekker Hansen, Brian Larsen Thorsted, Deniz Tutkunkardas, Mette Zacho & Hiroshi Maegawa. (2018) Clinical inertia in basal insulin-treated patients with type 2 diabetes – Results from a retrospective database study in Japan (JDDM 43). PLOS ONE 13:9, pages e0198160.
Crossref
Martha Sajatovic, Curtis Tatsuoka, Elisabeth Welter, Kari Colon-Zimmermann, Carol Blixen, Adam T. Perzynski, Shelly Amato, Jamie Cage, Johnny Sams, Shirley M. Moore, Svetlana Pundik, Sophia Sundararajan, Charles Modlin & Cathy Sila. (2017) A Targeted Self-Management Approach for Reducing Stroke Risk Factors in African American Men Who Have Had a Stroke or Transient Ischemic Attack. American Journal of Health Promotion 32:2, pages 282-293.
Crossref
Nicolaas C. Schaper, Annie Nikolajsen, Anna Sandberg, Sarah Buchs & Mette Bøgelund. (2017) Timing of Insulin Injections, Adherence, and Glycemic Control in a Multinational Sample of People with Type 2 Diabetes: A Cross-Sectional Analysis. Diabetes Therapy 8:6, pages 1319-1329.
Crossref
Draženka Pongrac Barlovič, Andrej Zavratnik, Aleš Skvarča, Karmen Janša, Bojana Vukelič, Marjeta Tomažič & Maja Ravnik Oblak. (2017) Self-reported hypoglycaemia in patients treated with insulin: A large Slovenian retrospectively-prospective study. Slovenian Journal of Public Health 56:4, pages 244-250.
Crossref
Yu-Hung Chang, Der-Wei Hwu, Dao-Ming Chang, Ling-Wang An, Chang-Hsun Hsieh & Yau-Jiunn Lee. (2017) Renal function preservation with pioglitazone or with basal insulin as an add-on therapy for patients with type 2 diabetes mellitus. Acta Diabetologica 54:6, pages 561-568.
Crossref
Akiko Nishimura, Shin-ichi Harashima, Haruna Fukushige, Yu Wang, Yanyan Liu, Kiminori Hosoda & Nobuya Inagaki. (2017) A Large Difference in Dose Timing of Basal Insulin Introduces Risk of Hypoglycemia and Overweight: A Cross-Sectional Study. Diabetes Therapy 8:2, pages 385-399.
Crossref
Samuel StolpeMichel A. KroesNeil WebbTami Wisniewski. (2016) A Systematic Review of Insulin Adherence Measures in Patients with Diabetes. Journal of Managed Care & Specialty Pharmacy 22:11, pages 1224-1246.
Crossref
Ming‐Nan Chien, Yen‐Ling Chen, Yi‐Jen Hung, Shu‐Yi Wang, Wen‐Tsung Lu, Chih‐Hung Chen, Ching‐Ling Lin, Tze‐Pao Huang, Ming‐Han Tsai, Wei‐Kung Tseng, Ta‐Jen Wu, Cheng Ho, Wen‐Yu Lin, Bill Chen & Lee‐Ming Chuang. (2016) Glycemic control and adherence to basal insulin therapy in Taiwanese patients with type 2 diabetes mellitus. Journal of Diabetes Investigation 7:6, pages 881-888.
Crossref
Takashi Kadowaki, Hideaki Jinnouchi, Kohei Kaku, Malene L Hersløv, Jacob Hyllested‐Winge & Shuji Nakamura. (2016) Efficacy and safety of once‐daily insulin degludec dosed flexibly at convenient times vs fixed dosing at the same time each day in a Japanese cohort with type 2 diabetes: A randomized, 26‐week, treat‐to‐target trial. Journal of Diabetes Investigation 7:5, pages 711-717.
Crossref
Michael Vallis, K. Kovacs Burns, Debbie Hollahan, Stuart Ross & Jina Hahn. (2016) Diabetes Attitudes, Wishes and Needs Second Study (DAWN2): Understanding Diabetes-Related Psychosocial Outcomes for Canadians with Diabetes. Canadian Journal of Diabetes 40:3, pages 234-241.
Crossref
Matthew C. RiddleGeremia B. BolliPhilip D. HomeRichard M. BergenstalMonika ZiemenIsabel Muehlen-BartmerMarek WardeckiLaetitia VinetNathalie JeandidierHannele Yki-Järvinen. (2016) Efficacy and Safety of Flexible Versus Fixed Dosing Intervals of Insulin Glargine 300 U/mL in People with Type 2 Diabetes. Diabetes Technology & Therapeutics 18:4, pages 252-257.
Crossref
Kam CapocciaPeggy S. OdegardNancy Letassy. (2015) Medication Adherence With Diabetes Medication. The Diabetes Educator 42:1, pages 34-71.
Crossref
Allen B. King. (2015) Misled by the Morning “Fasting” Plasma Glucose. Journal of Diabetes Science and Technology 9:6, pages 1342-1345.
Crossref
S. Halimi. (2015) Perspectives pour améliorer la prise en charge des patients diabétiques de type 2 sous insuline. Médecine des Maladies Métaboliques 9:3, pages 3S34-3S42.
Crossref
S. Halimi. (2015) Severe hypoglycaemia the “tip of the iceberg”: An underestimated risk in both type 1 and type 2 diabetic patients. Diabetes & Metabolism 41:2, pages 105-106.
Crossref
Mohammed Kalkattawi & Tatsuo Nakajima. 2015. Human Interface and the Management of Information. Information and Knowledge Design. Human Interface and the Management of Information. Information and Knowledge Design 535 546 .
Francisco J. Ampudia-Blasco, Manuel Galán & Meryl Brod. (2014) A cross-sectional survey among patients and prescribers on insulin dosing irregularities and impact of mild (self-treated) hypoglycemia episodes in Spanish patients with type 2 diabetes as compared to other European patients. Endocrinología y Nutrición 61:8, pages 426-433.
Crossref
Francisco J. Ampudia-Blasco, Manuel Galán & Meryl Brod. (2014) A cross-sectional survey among patients and prescribers on insulin dosing irregularities and impact of mild (self-treated) hypoglycemia episodes in Spanish patients with type 2 diabetes as compared to other European patients. Endocrinología y Nutrición (English Edition) 61:8, pages 426-433.
Crossref
Jörg Lüdemann, Karsten Milek, Birgit Wilhelm, Alexander Segner & Elmar Jaeckel. (2014) Tageszeitlich flexible Gabe von Insulin degludec bei Patienten mit Typ-1-Diabetes oder Typ-2-DiabetesDaytime flexible application of Insulin degludec in patients with type 1 diabetes or type 2 diabetes. MMW - Fortschritte der Medizin 156:S5, pages 89-97.
Crossref
John G. Ryan. (2014) Will Inhalable Insulin Reduce Medication Nonadherence With Insulin Among People With Diabetes?. Clinical Therapeutics 36:8, pages 1309-1312.
Crossref
N. Munro & A. H. Barnett. (2014) Incidence, worry and discussion about dosing irregularities and self-treated hypoglycaemia amongst HCPs and patients with type 2 diabetes: results from the UK cohort of the Global Attitudes of Patient and Physicians (GAPP2) survey. International Journal of Clinical Practice 68:6, pages 692-699.
Crossref
Susan Stockley. (2014) Characteristics and practicalities of a new basal insulin. British Journal of Nursing 23:1, pages 16-20.
Crossref
Francisco Javier Ampudia-Blasco. (2014) Aspectos clínicamente relevantes para pacientes diabéticos en tratamiento con insulina: prevención de hipoglucemias y flexibilidad en la administración. Avances en Diabetología 30:1, pages 1-8.
Crossref
Baptist Gallwitz & Thomas Haak. (2013) Insulin degludec — ein neues Basalinsulin zur Behandlung von Typ-1- und Typ-2-DiabetesInsulin degludec — a new basal insulin for the treatment of type 1 and type 2 diabetes. MMW - Fortschritte der Medizin 155:S5, pages 76-82.
Crossref
Luigi Meneghini, Stephen L. AtkinStephen C.L. GoughItamar Raz, Lawrence Blonde, Marina Shestakova, Stephen BainThue Johansen, Kamilla Begtrup & Kåre I. Birkeland. (2013) The Efficacy and Safety of Insulin Degludec Given in Variable Once-Daily Dosing Intervals Compared With Insulin Glargine and Insulin Degludec Dosed at the Same Time Daily. Diabetes Care 36:4, pages 858-864.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.