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Research Articles

A randomized, double-blind, placebo-controlled study of the efficacy and safety of MNK-795, a dual-layer, biphasic, immediate-release and extended-release combination analgesic for acute pain

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Pages 349-359 | Accepted 16 Dec 2013, Published online: 10 Jan 2014

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Tiffani D. Eisenhauer, Mike Matchett, Ralph Heasley, Terri Morton, Krishna Devarakonda, Michael Giuliani, Jim L. Young & Thomas Barrett. (2016) Evaluation of the tamper-resistant properties of biphasic immediate-release/extended-release oxycodone/acetaminophen tablets. Drug Development and Industrial Pharmacy 42:1, pages 157-165.
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Neil Singla, Rachel Margulis, Kenneth Kostenbader, Yanping Zheng, Thomas Barrett, Michael J. Giuliani, Yin Chen & Jim L. Young. (2015) Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain. The Physician and Sportsmedicine 43:2, pages 126-137.
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Neil Singla, Thomas Barrett, Lisa Sisk, Kenneth Kostenbader & Jim Young. (2014) Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery. Current Medical Research and Opinion 30:12, pages 2571-2578.
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Oscar de Leon-Casasola. (2014) A Review of the Literature on Multiple Factors Involved in Postoperative Pain Course and Duration. Postgraduate Medicine 126:4, pages 42-52.
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Terri Morton, Kenneth Kostenbader, Jeannie Montgomery, Krishna Devarakonda, Thomas Barrett & Lynn Webster. (2014) Comparison of Subjective Effects of Extended-Release Versus Immediate-Release Oxycodone/Acetaminophen Tablets in Healthy Nondependent Recreational Users of Prescription Opioids: A Randomized Trial. Postgraduate Medicine 126:4, pages 20-32.
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Articles from other publishers (5)

Richard D Berkowitz, Richard Steinfeld, Alexander P Sah, Randall J Mack, Stewart W McCallum, Wei Du, Libby K Black, Alex Freyer & Erin Coyle. (2021) Safety and Efficacy of Perioperative Intravenous Meloxicam for Moderate-to-Severe Pain Management in Total Knee Arthroplasty: A Randomized Clinical Trial. Pain Medicine 22:6, pages 1261-1271.
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Neil K. Singla, Diana S. Meske & Paul J. Desjardins. (2017) Exploring the Interplay between Rescue Drugs, Data Imputation, and Study Outcomes: Conceptual Review and Qualitative Analysis of an Acute Pain Data Set. Pain and Therapy 6:2, pages 165-175.
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Thomas BarrettKenneth KostenbaderSrinivas NalamachuMichael GiulianiJim L. Young. (2015) Safety and Tolerability of Biphasic Immediate‐Release/Extended‐Release Oxycodone/Acetaminophen Tablets: Analysis of 11 Clinical Trials. Pain Practice 16:7, pages 856-868.
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Joseph V. PergolizziJr.Jr., Robert TaylorJr.Jr. & Robert B. Raffa. (2015) The Potential Role of an Extended-Release, Abuse-Deterrent Oxycodone/Acetaminophen Fixed-Dose Combination Product for the Treatment of Acute Pain. Advances in Therapy 32:6, pages 485-495.
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Steven D. Passik. (2014) Tamper-Resistant Opioid Formulations in the Treatment of Acute Pain. Advances in Therapy 31:3, pages 264-275.
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