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Current Medical Research and Opinion Volume 30, 2014 - Issue 8
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Psychiatry: Review articles

A review of real-world data on the effects of aripiprazole on weight and metabolic outcomes in adults

Leslie CitromeNew York Medical College Valhalla, NYUSACorrespondence[email protected]
,
Iftekhar KalsekarBristol-Myers Squibb Plainsboro, NJUSA
,
Ross A. BakerOtsuka Pharmaceutical Development & Commercialization Inc. Princeton, NJUSA
&
Tony HebdenBristol-Myers Squibb Plainsboro, NJUSA
Pages 1629-1641 | Accepted 19 Mar 2014, Published online: 19 May 2014

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L. Orsolini, C. Tomasetti, A. Valchera, R. Vecchiotti, I. Matarazzo, F. Vellante, F. Iasevoli, E. F. Buonaguro, M. Fornaro, A. L. C. Fiengo, G. Martinotti, M. Mazza, G. Perna, A. Carano, A. De Bartolomeis, M. Di Giannantonio & D. De Berardis. (2016) An update of safety of clinically used atypical antipsychotics. Expert Opinion on Drug Safety 15:10, pages 1329-1347.
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Ricardo P. Garay, Leslie Citrome, George T. Grossberg, Icilio Cavero & Pierre-Michel Llorca. (2016) Investigational drugs for treating agitation in persons with dementia. Expert Opinion on Investigational Drugs 25:8, pages 973-983.
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Leslie Citrome, Anna Eramo, Clement Francois, Ruth Duffy, Susan N Legacy, Steve J Offord, Holly B Krasa, Stephen S Johnston, Alice Guiraud-Diawara, Siddhesh A Kamat & Patricia Rohman. (2015) Lack of tolerable treatment options for patients with schizophrenia. Neuropsychiatric Disease and Treatment 11, pages 3095-3104.
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Richard Musil, Michael Obermeier, Paul Russ & Michael Hamerle. (2015) Weight gain and antipsychotics: a drug safety review. Expert Opinion on Drug Safety 14:1, pages 73-96.
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Matisyahu Shulman, Avraham Miller, Jason Misher & Aleksey Tentler. (2014) Managing cardiovascular disease risk in patients treated with antipsychotics: a multidisciplinary approach. Journal of Multidisciplinary Healthcare 7, pages 489-501.
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Articles from other publishers (27)

David J. Robinson, Kimberley Hanson, Akshay B. Jain, Jessica C. Kichler, Gaurav Mehta, Osnat C. Melamed, Michael Vallis, Harpreet S. Bajaj, Tracy Barnes, Jeremy Gilbert, Kristin Honshorst, Robyn Houlden, James Kim, Joanne Lewis, Barbara MacDonald, Dylan MacKay, Kerry Mansell, Doreen Rabi, Diana Sherifali & Peter Senior. (2023) Diabetes and Mental Health. Canadian Journal of Diabetes 47:4, pages 308-344.
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Caitlin B. Shepherd, Rebecca G. Boswell, Jessica Genet, Wendy Oliver-Pyatt, Christine Stockert, Rebecca Brumm, Shaun Riebl & Elsbeth Crowe. (2023) Outcomes for binge eating disorder in a remote weight-inclusive treatment program: a case report. Journal of Eating Disorders 11:1.
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Marta Balog, Allison C Anderson, Marija Heffer, Zeljka Korade & Karoly Mirnics. (2022) Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice. Biomolecules 12:10, pages 1535.
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Marta Balog, Allison Anderson, Thiago C. Genaro-Mattos, Zeljka Korade & Karoly Mirnics. (2022) Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain. Journal of Lipid Research 63:8, pages 100249.
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Lu Han, Tim Doran, Richard Ian Gregory Holt, Catherine Hewitt, Rowena Jacobs, Stephanie Louise Prady, Sarah Louise Alderson, David Shiers, Han-I Wang, Sue Bellass, Simon Gilbody, Charlotte Emma Wray Kitchen, Jennie Lister, Johanna Taylor & Najma Siddiqi. (2021) Impact of severe mental illness on healthcare use and health outcomes for people with type 2 diabetes: a longitudinal observational study in England. British Journal of General Practice 71:709, pages e565-e573.
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De-juan Li, Qin Yue, Lu Liu, Ke-ke Che, Xue-mei Liu & Chang-hua Hu. (2021) Brexpiprazole caused glycolipid metabolic disorder by inhibiting GLP1/GLP1R signaling in rats. Acta Pharmacologica Sinica 42:8, pages 1267-1279.
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Jennie Lister, Lu Han, Sue Bellass, Jo Taylor, Sarah L Alderson, Tim Doran, Simon Gilbody, Catherine Hewitt, Richard IG Holt, Rowena Jacobs, Charlotte EW Kitchen, Stephanie L Prady, John Radford, Jemimah R Ride, David Shiers, Han-I Wang & Najma Siddiqi. (2021) Identifying determinants of diabetes risk and outcomes for people with severe mental illness: a mixed-methods study. Health Services and Delivery Research 9:10, pages 1-194.
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Е.А. Хаустова. (2021) Metabolic Profile of Patients with Schizophrenia. Психиатрия, психотерапия и клиническая психология:4, pages 764-778.
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Sanghoon Oh, Tae Young Lee, Minah Kim, Se Hyun Kim, Suehyun Lee, Sunwoo Cho, Ju Han Kim & Jun Soo Kwon. (2020) Effectiveness of antipsychotic drugs in schizophrenia: a 10-year retrospective study in a Korean tertiary hospital. npj Schizophrenia 6:1.
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Nicholas Keks, Judith Hope, Darren Schwartz, Harold McLennan, David Copolov & Graham Meadows. (2020) Comparative Tolerability of Dopamine D2/3 Receptor Partial Agonists for Schizophrenia. CNS Drugs 34:5, pages 473-507.
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Jean-Michel Azorin & Nicolas Simon. (2019) Dopamine Receptor Partial Agonists for the Treatment of Bipolar Disorder. Drugs 79:15, pages 1657-1677.
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Richard I. G. Holt. (2019) Association Between Antipsychotic Medication Use and Diabetes. Current Diabetes Reports 19:10.
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Trude S. Jahr Vedal, Nils Eiel Steen, Kåre I. Birkeland, Ingrid Dieset, Elina J. Reponen, Jannicke F. Laskemoen, Linn Rødevand, Ingrid Melle, Ole A. Andreassen, Espen Molden & Erik G. Jönsson. (2019) Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI. Psychoneuroendocrinology 103, pages 87-95.
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Bunta Yoshimura, Kojiro Sato, Manabu Takaki & Norihito Yamada. (2019) Algorithm-based pharmacotherapy for first-episode schizophrenia involuntarily hospitalized: A retrospective analysis of real-world practice. Early Intervention in Psychiatry 13:1, pages 39-46.
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Baybars Veznedaroglu, Nesrin Dilbaz, Ozcan Uzun & Erdal Isik. (2018) TARC: Turkish aripiprazole consensus report- Aripiprazole use and switching from other antipsychotics to aripiprazole- consensus recommendations by a Turkish multidisciplinary panel. Therapeutic Advances in Psychopharmacology 8:10, pages 271-285.
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Clare A Whicher, Hermione C Price & Richard I G Holt. (2018) Mechanisms in endocrinology: Antipsychotic medication and type 2 diabetes and impaired glucose regulation. European Journal of Endocrinology 178:6, pages R245-R258.
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Sangho Shin, Seoyoung Kim, Seongho Seo, Jae Sung Lee, Oliver D. Howes, Euitae Kim & Jun Soo Kwon. (2018) The relationship between dopamine receptor blockade and cognitive performance in schizophrenia: a [11C]-raclopride PET study with aripiprazole. Translational Psychiatry 8:1.
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Chan Gil, Yu Kim, Hong Lee, Da Jung, Hwa Shin & Byung Choi. (2017) Aripiprazole exerts a neuroprotective effect in mouse focal cerebral ischemia. Experimental and Therapeutic Medicine.
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Se Jin Jeon, Eunji Kim, Jin Su Lee, Hee Kyong Oh, Jiabao Zhang, Yubeen Kwon, Dae Sik Jang & Jong Hoon Ryu. (2017) Maslinic acid ameliorates NMDA receptor blockade-induced schizophrenia-like behaviors in mice. Neuropharmacology 126, pages 168-178.
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Alexandre Salvador, Yulia Worbe, Cécile Delorme, Giorgio Coricelli, Raphaël Gaillard, Trevor W. Robbins, Andreas Hartmann & Stefano Palminteri. (2017) Specific effect of a dopamine partial agonist on counterfactual learning: evidence from Gilles de la Tourette syndrome. Scientific Reports 7:1.
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Ashok Malla, Sally Mustafa, Aldanie Rho, Sherezad Abadi, Martin Lepage & Ridha Joober. (2016) Therapeutic effectiveness and tolerability of aripiprazole as initial choice of treatment in first episode psychosis in an early intervention service: A one-year outcome study. Schizophrenia Research 174:1-3, pages 120-125.
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David Arterburn, G. Craig Wood, Mary Kay Theis, Emily O. Westbrook, Jane Anau, Margaret Rukstalis, Joseph A. Boscarino, Zahra Daar & Glenn S. Gerhard. (2016) Antipsychotic medications and extreme weight gain in two health systems. Obesity Research & Clinical Practice 10:4, pages 408-423.
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Valentina Medici, Stephen A. McClave & Keith R. Miller. (2015) Common Medications Which Lead to Unintended Alterations in Weight Gain or Organ Lipotoxicity. Current Gastroenterology Reports 18:1.
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Inna D’Empaire, Sheldon H. Preskorn & Matthew Macaluso. 2016. The Medical Basis of Psychiatry. The Medical Basis of Psychiatry 655 670 .
Ingeborg Bolstad, Ole A. Andreassen, Inge R. Groote, Beathe Haatveit, Andres Server & Jimmy Jensen. (2015) No difference in frontal cortical activity during an executive functioning task after acute doses of aripiprazole and haloperidol. Frontiers in Human Neuroscience 9.
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Eiji Kirino. (2015) Use of aripiprazole for delirium in the elderly: a short review. Psychogeriatrics 15:1, pages 75-84.
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P. Chue & G. Baker. 2015. A worldwide yearly survey of new data in adverse drug reactions. A worldwide yearly survey of new data in adverse drug reactions 63 83 .

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