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Neurology: Review article

Diagnosis, comorbidities, and management of restless legs syndrome

&
Pages 1441-1460 | Accepted 22 Apr 2014, Published online: 09 May 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Ashley M. Pfeiffer, Craig Triplett & Catherine F. Siengsukon. (2022) Examining the prevalence of sleep disturbances in patients seeking physical therapy services. Physiotherapy Theory and Practice 0:0, pages 1-9.
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Eloise G. Harrison, Jennifer L. Keating & Prue E. Morgan. (2019) Non-pharmacological interventions for restless legs syndrome: a systematic review of randomised controlled trials. Disability and Rehabilitation 41:17, pages 2006-2014.
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Marco Zucconi, Andrea Galbiati, Fabrizio Rinaldi, Francesca Casoni & Luigi Ferini-Strambi. (2018) An update on the treatment of Restless Legs Syndrome/Willis-Ekbom Disease: prospects and challenges. Expert Review of Neurotherapeutics 18:9, pages 705-713.
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Christopher W Drapeau & Michael R Nadorff. (2017) Suicidality in sleep disorders: prevalence, impact, and management strategies. Nature and Science of Sleep 9, pages 213-226.
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Manjit K Sanghera, Samantha G Sales, Jennifer L Robinson, Juhee Song, Elmyra V Encarnacion & R Malcolm Stewart. (2015) Restless legs syndrome: associated non-motor symptoms and medical comorbidities: a controlled study. Journal of Parkinsonism and Restless Legs Syndrome 5, pages 33-38.
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Anne M. Ryschon, Khoa N. Cao, Asim Roy & Jan B. Pietzsch. (2023) Cost-Effectiveness of Tonic Motor Activation (TOMAC) Therapy for Patients with Restless Legs Syndrome: An Exploratory Analysis. Neurology and Therapy 12:6, pages 2133-2146.
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Rashad İSMAYILOV & Yıldız DEĞİRMENCİ. (2023) Restless Legs Syndrome: From Diagnosis to TreatmentHuzursuz Bacaklar Sendromu: Tanıdan Tedaviye. Düzce Tıp Fakültesi Dergisi.
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Amina Sadaqat, Kainat Ahmar, Hafiza Rabia Javed, Ayesha Hamid & Hira Shahid. (2023) Effect of Lower Limb Strengthening Exercises on Severity of Restless Leg Syndrome among Diabetic Patients: A Time Series Study. Pakistan Journal of Health Sciences, pages 278-283.
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Rohit Kumar, Vijay Krishnan, Anindya Das, Niraj Kumar & Ravi Gupta. (2023) Modification and Validation of a Diagnostic Questionnaire for Restless Legs Syndrome. Annals of Indian Academy of Neurology Publish Ahead of Print.
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Berna Solak, Büşra Aydın, Gülcan Yüksekal & Mahizer Yaldız. (2022) Restless legs syndrome in patients with psoriasis: association with inflammation and sleep quality. International Journal of Dermatology 62:4, pages 501-507.
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Hülya Olgun, Tamer Yazar, BernaB Çakmak & YelizK Arıcı. (2023) Assessment of Sleep Disturbances on Mental Health in Patients with Restless Legs Syndrome. Neurology India 71:4, pages 693.
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Ravi Yadav, Maryam RA Altuhafy, Sandeep Talluri, Luay Jabr, Mythili Kalladka & Junad Khan. (2022) The Efficacy of Botulinum Toxin in the Management of Restless Leg Syndrome: A Systematic Review of Randomized Control Trials. Indian Journal of Sleep Medicine 17:1, pages 15-21.
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Lucija Čondić Jurjević & Srđana Telarović. (2022) Relationship of restless legs syndrome with number of pregnancies, duration of pregnancy and positive family history. Women's Health 18, pages 174550572211093.
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Subrahmanian Sathiavageesan, Ishwarya Annamalai, Arunkarki Malayappan, Kamalanathan Melchizedek, Ranjitha Ramajayam & Anjali Annadurai. (2021) Restless leg syndrome presenting as chronic severe limb pain in a dialysis patient. Hemodialysis International 26:1.
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Hikmet SAÇMACI & Mesude KİSLİ. (2021) TIBIAL NERVE CONDUCTION IN PATIENTS WITH RESTLESS LEGS SYNDROMEHuzursuz Bacak Sendromlu Hastalarda Tibial Sinir İletimi. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 23:2, pages 236-244.
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Ravi Gupta, Rohit Gupta, Niraj Kumar, Vikram Singh Rawat, Jan Ulfberg & Richard Putnam Allen. (2021) Restless legs syndrome among subjects having chronic liver disease: A systematic review and meta-analysis. Sleep Medicine Reviews 58, pages 101463.
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Eloise G Harrison, Jennifer L Keating & Prue E Morgan. (2019) The experience of living with restless legs syndrome: A qualitative study. Journal of Health Psychology 26:8, pages 1154-1167.
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Eus J. W. Van Someren. (2021) Brain mechanisms of insomnia: new perspectives on causes and consequences. Physiological Reviews 101:3, pages 995-1046.
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Arunima Roy, Christopher J. Earley, Richard P. Allen & Zachary A. Kaminsky. (2021) Developing a biomarker for restless leg syndrome using genome wide DNA methylation data. Sleep Medicine 78, pages 120-127.
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Anastasios Bonakis, Anastasia Androutsou, Maria-Evangelia Koloutsou & Emmanouil Vagiakis. (2020) Restless Legs Syndrome masquerades as chronic insomnia. Sleep Medicine 75, pages 106-111.
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Arantxa Blasco‐Serra, Gloria Alfosea‐Cuadrado, Ana Cervera‐Ferri, Eva M. González‐Soler, Ana Lloret, Joana Martínez‐Ricós, Vicent Teruel‐Martí & Alfonso A. Valverde‐Navarro. (2019) Hippocampal oscillatory dynamics and sleep atonia are altered in an animal model of fibromyalgia: Implications in the search for biomarkers. Journal of Comparative Neurology 528:8, pages 1367-1391.
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K. Pitarokoili, M. Fels, A. Kerasnoudis, L. Tönges, R. Gold & M.-S. Yoon. (2018) High-Resolution Nerve Ultrasound and Electrophysiological Findings in Restless Legs Syndrome. Journal of Neuroimaging 28:5, pages 506-514.
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Maria Didriksen, Richard P. Allen, Brendan J. Burchell, Lise W. Thørner, Andreas S. Rigas, Emanuele Di Angelantonio, Maria H. Nielsen, Poul J. Jennum, Thomas Werge, Christian Erikstrup, Ole B. Pedersen, Kaspar Nielsen, Mie T. Bruun, Kristoffer S. Burgdorf, Erik Sørensen & Henrik Ullum. (2018) Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors. Sleep Medicine 45, pages 124-131.
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Xiao-Min Xu, Yang Liu, Shi-Yu Jia, Mei-Xue Dong, Du Cao & You-Dong Wei. (2018) Complementary and alternative therapies for restless legs syndrome: An evidence-based systematic review. Sleep Medicine Reviews 38, pages 158-167.
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Juhyeun Kim & Abraham G. Hartzema. (2018) Adherence and persistence to ropinirole, pramipexole, and gabapentin in patients with newly diagnosed restless legs syndrome. Sleep Medicine 44, pages 45-52.
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Mandy Roy, Martina de Zwaan, Inka Tuin, Alexandra Philipsen, Elmar Brähler & Astrid Müller. (2015) Association Between Restless Legs Syndrome and Adult ADHD in a German Community-Based Sample. Journal of Attention Disorders 22:3, pages 300-308.
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Maria Didriksen, Thomas F Hansen, Lise W Thørner, Kristoffer S Burgdorf, Christian Erikstrup, Ole B Pedersen, Helene M Paarup, Kaspar R Nielsen, Henrik Hjalgrim, Erik Sørensen & Henrik Ullum. (2018) Restless legs syndrome is associated with increased risk of migraine. Cephalalgia Reports 1, pages 251581631878074.
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