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Current Medical Research and Opinion Volume 31, 2015 - Issue 2
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Original article

Evaluation of the pharmacokinetics of the DPP-4 inhibitor gemigliptin when coadministered with rosuvastatin or irbesartan to healthy subjects

Hee Youn ChoiDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Hyeong-Seok LimDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Yo Han KimDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Hae Sun JeonDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Mi Jo KimDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Shi Hyang LeeDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
,
Jong Hyuk JungLG Life Sciences Ltd, Seoul, Korea
,
Young Kyoung LeeLG Life Sciences Ltd, Seoul, Korea
,
Hyun Jeong KimLG Life Sciences Ltd, Seoul, Korea
&
Kyun-Seop BaeDepartment of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaCorrespondence[email protected]
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Pages 229-241 | Accepted 10 Oct 2014, Published online: 06 Nov 2014

Citations (9)

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Eunsol Yang, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu & SeungHwan Lee. (2021) Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study. Drug Design, Development and Therapy 15, pages 651-658.
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Takeshi Hirota, Yuito Fujita & Ichiro Ieiri. (2020) An updated review of pharmacokinetic drug interactions and pharmacogenetics of statins. Expert Opinion on Drug Metabolism & Toxicology 16:9, pages 809-822.
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Eunwoo Kim, Kyoung Ryun Park, In-Jin Jang, Kyung-Sang Yu & SeungHwan Lee. (2019) A Fixed-Dose Combination Of Gemigliptin And Rosuvastatin Exhibits Similar Pharmacokinetics, Pharmacodynamics, And Safety Compared To That Of A Loose Combination In Healthy Subjects. Drug Design, Development and Therapy 13, pages 3879-3885.
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Articles from other publishers (6)

Chang-Keun Cho, Pureum Kang, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee & Chang-Ik Choi. (2023) Physiologically based pharmacokinetic (PBPK) modeling to predict the pharmacokinetics of irbesartan in different CYP2C9 genotypes. Archives of Pharmacal Research.
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Tao He, Mingshuang Wang, Jiao Kong, Qiang Wang, Yue Tian, Chaofeng Li, Qian Wang, Chuanxin Liu & Jianmei Huang. (2022) Integrating network pharmacology and non-targeted metabolomics to explore the common mechanism of Coptis Categorized Formula improving T2DM zebrafish. Journal of Ethnopharmacology 284, pages 114784.
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Raju Kanukula, Abdul Salam, Anthony Rodgers & Bishoy Kamel. (2021) Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults. Clinical Pharmacokinetics 60:2, pages 165-175.
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Jaehyun Bae, Youjin Kim, Yongin Cho, Minyoung Lee, Ji-Yeon Lee, Yong-ho Lee, Byung-Wan Lee, Bong-Soo Cha, Dong Jin Joo, Kyu Ha Huh, Myoung Soo Kim, Yu Seun Kim & Eun Seok Kang. (2019) Efficacy and Safety of Gemigliptin in Post-Transplant Patients With Type 2 Diabetes Mellitus. Transplantation Proceedings 51:10, pages 3444-3448.
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Naina Mohamed Pakkir Maideen. (2019) Drug interactions of dipeptidyl peptidase 4 inhibitors involving CYP enzymes and P-gp efflux pump. World Journal of Meta-Analysis 7:4, pages 156-161.
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Sung-Ho KimJung-Hwa YooWoo Je LeeCheol-Young Park. (2016) Gemigliptin: An Update of Its Clinical Use in the Management of Type 2 Diabetes Mellitus. Diabetes & Metabolism Journal 40:5, pages 339.
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