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Isabella Skye Waddell & Caroline Orfila. (2023) Dietary fiber in the prevention of obesity and obesity-related chronic diseases: From epidemiological evidence to potential molecular mechanisms. Critical Reviews in Food Science and Nutrition 63:27, pages 8752-8767.
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Read now
Kenneth Blum, EricR. Braverman, JayM. Holder, JoelF. Lubar, VincentJ. Monastra, David Miller, JudithO. Lubar, ThomasJ.H. Chen & DavidE. Comings. (2000) The Reward Deficiency Syndrome: A Biogenetic Model for the Diagnosis and Treatment of Impulsive, Addictive and Compulsive Behaviors. Journal of Psychoactive Drugs 32:sup1, pages 1-112.
Read now
Read now
S. Caccia, A. Bergami, C. Fracasso, S. Garattini & B. Campbell. (1995) Oral kinetics of dexfenfluramine and dexnorfenfluramine in non-human primates. Xenobiotica 25:10, pages 1143-1150.
Read now
Read now
N. C. Marchant, M. A. Breen, D. Wallace, S. Bass, A. R. Taylor, R. M. J. Ings, D. B. Campbell & J. Williams. (1992) Comparative biodisposition and metabolism of 14C-(±)-fenfluramine in mouse, rat, dog and man. Xenobiotica 22:11, pages 1251-1266.
Read now
Read now
S. Caccia, M. Anelli, A. Ferrarese, C. Fracasso & S. Garattini. (1992) Single- and multiple-dose kinetics of d-fenfluramine in rats given anorectic and toxic doses. Xenobiotica 22:2, pages 217-226.
Read now
Read now
R. Spinelli, C. Fracasso, G. Guiso, S. Garattini & S. Caccia. (1988) Disposition of (—)-fenfluramine and its active metabolite, (—)-norfenfluramine in rat: A single dose-proportionality study. Xenobiotica 18:5, pages 573-584.
Read now
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Articles from other publishers (132)
Reem Odi, Roberto William Invernizzi, Tamar Gallily, Meir Bialer & Emilio Perucca. (2021) Fenfluramine repurposing from weight loss to epilepsy: What we do and do not know. Pharmacology & Therapeutics 226, pages 107866.
Crossref
Crossref
Erman Syahruddin, Rita Herawaty & Azhar .. (2019) Substituting Soybean Meal with Fermented Leaves and Seeds of Rubber Trees (Hevea brasiliensis): Effects on Carcass Percentage, Abdominal Fat Percentage and Meat-to-Bone Ratio in Broiler Chickens. International Journal of Poultry Science 18:9, pages 416-422.
Crossref
Crossref
Rahul S. Pawar & Erich Grundel. (2016) Overview of regulation of dietary supplements in the USA and issues of adulteration with phenethylamines (PEAs). Drug Testing and Analysis 9:3, pages 500-517.
Crossref
Crossref
Andrew J. Grottick, Kevin Whelan, Erin K. Sanabria, Dominic P. Behan, Michael Morgan & Carleton Sage. (2014) Investigating interactions between phentermine, dexfenfluramine, and 5-HT2C agonists, on food intake in the rat. Psychopharmacology 232:11, pages 1973-1982.
Crossref
Crossref
María J. Mancebo, Francisco C. Ceballos, Jorge Pérez-Maceira & Manuel Aldegunde. (2013) Hypothalamic neuropeptide Y (NPY) gene expression is not affected by central serotonin in the rainbow trout (Oncorhynchus mykiss). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 166:1, pages 186-190.
Crossref
Crossref
Joanne P. Boisvert, Tyler J. Boschuetz, Jon M. Resch, Christopher R. Mueller & SuJean Choi. (2011) Serotonin mediated changes in corticotropin releasing factor mRNA expression and feeding behavior isolated to the hypothalamic paraventricular nuclei. Neuroscience Letters 498:3, pages 213-217.
Crossref
Crossref
C Bendotti, S Garattini & R Samanin. (1987) Eating caused by neuropeptide-Y injection in the paraventricular hypothalamus: response to (+)-fenfluramine and (+)-amphetamine in rats. Journal of Pharmacy and Pharmacology 39:11, pages 900-903.
Crossref
Crossref
C Bendotti, S Garattini & R Samanin. (1986) Hypherphagia caused by muscimol injection in the nucleus raphe dorsalis of rats: its control by 5-hydroxytryptamine in the nucleus accumbens. Journal of Pharmacy and Pharmacology 38:7, pages 541-543.
Crossref
Crossref
U Spampinato, E Nowakowska & R Samanin. (1983) Increased release of striatal dopamine after long-term treatment with methadone in rats: inhibition by agents which increase central 5-hydroxytryptamine transmission. Journal of Pharmacy and Pharmacology 35:12, pages 831-833.
Crossref
Crossref
JOSEPH A HIRSCHSCOT GOLDBERGRICHARD J WURTMAN. (1982) Effect of (+)- or (−)-enantiomers of fenfluramine or norfenfluramine on nutrient selection by rats. Journal of Pharmacy and Pharmacology 34:1, pages 18-21.
Crossref
Crossref
T Mennini, R Pataccini, V Crunelli, S Caccia, M Ballabio, R Samanin & S Garattini. (1980) Localization of fenfluramine and reserpine in brain regions of rats with extensive degeneration of 5-hydroxytryptaminergic neurons. Journal of Pharmacy and Pharmacology 32:1, pages 505-507.
Crossref
Crossref
S Consolo, H Ladinsky, G L Forloni, A S Tirelli & S Garattini. (1980) Comparison of the effects of the stereoisomers of fenfluramine on the acetylcholine content of rat striatum, hippocampus and nucleus accumbens. Journal of Pharmacy and Pharmacology 32:1, pages 201-203.
Crossref
Crossref
S Consolo, G L Forloni, S Garattini, H Ladinsky & A S Tirelli. (1979) Differential effects of the isomers of fenfluramine and norfenfluramine on rat striatal acetylcholine content. Journal of Pharmacy and Pharmacology 31:1, pages 706-706.
Crossref
Crossref
SuJean Choi, Valarie Blake, Sara Cole & John D. Fernstrom. (2006) Effects of chronic fenfluramine administration on hypothalamic neuropeptide mRNA expression. Brain Research 1087:1, pages 83-86.
Crossref
Crossref
M. Eriksson, U. Berggren, C. Fahlke, J. Engel & J. Balldin. (2005) Platelet monoamine oxidase B (MAO-B) activity and its relationship to DL-fenfluramine-induced prolactin response in healthy men. Journal of Neural Transmission 113:1, pages 33-41.
Crossref
Crossref
M. Dolan, I. M. Anderson & J. F. W. Deakin. (2018) Relationship between 5-HT function and impulsivity and aggression in male offenders with personality disorders. British Journal of Psychiatry 178:4, pages 352-359.
Crossref
Crossref
Julie K Staley, Christopher H Van Dyck, Ping-Zhong Tan, Mohammed Al Tikriti, Quinn Ramsby, Heide Klump, Chin Ng, Pradeep Garg, Robert Soufer, Ronald M Baldwin & Robert B Innis. (2001) Comparison of [18F]altanserin and [18F]deuteroaltanserin for PET imaging of serotonin2A receptors in baboon brain: pharmacological studies. Nuclear Medicine and Biology 28:3, pages 271-279.
Crossref
Crossref
Paul J Schwartz, Erick H Turner, Diego Garcia-Borreguero, Jan Sedway, Rina G Vetticad, Thomas A Wehr, Dennis L Murphy & Norman E Rosenthal. (1999) Serotonin hypothesis of winter depression: behavioral and neuroendocrine effects of the 5-HT1A receptor partial agonist ipsapirone in patients with seasonal affective disorder and healthy control subjects. Psychiatry Research 86:1, pages 9-28.
Crossref
Crossref
T.M. Andrews & I.M. Anderson. (2016) Information processing in anxiety: a pilot study of the effect of manipulating 5-HT function. Journal of Psychopharmacology 12:2, pages 155-160.
Crossref
Crossref
Lisa E. Vivero, Philip O. Anderson & Richard F. Clark. (1998) A close look at fenfluramine and dexfenfluramine. The Journal of Emergency Medicine 16:2, pages 197-205.
Crossref
Crossref
Nicholas V Cozzi, Stewart Frescas, Danuta Marona-Lewicka, Xuemei Huang & David E Nichols. (1998) Indan Analogs of Fenfluramine and Norfenfluramine Have Reduced Neurotoxic Potential. Pharmacology Biochemistry and Behavior 59:3, pages 709-715.
Crossref
Crossref
Peter B. F. Bergqvist, Stephan Hjorth, Cecilia Wikell, Gustav Apelqvist & Finn Bengtsson. (1997) p-chloroamphetamine- and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy. Metabolic Brain Disease 12:3, pages 229-236.
Crossref
Crossref
Krishna P Datla & Gerald Curzon. (1997) The effect of d-fenfluramine on brain 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in male and female rats. European Journal of Pharmacology 333:1, pages 27-31.
Crossref
Crossref
Martin D. Schechte. (1997) Serotonergic mediation of fenfluramine discriminative stimuli in Fawn-Hooded rats. Life Sciences 60:6, pages 83-90.
Crossref
Crossref
Cyril Rocher, Lionel Bert, Frédéric Robert, Jean-Hugues Trouvin, Bernard Renaud, Christian Jacquot & Alain M Gardier. (1996) Microdialysis monitoring of variations in extracellular levels of serotonin, GABA and excitatory amino acids in the frontal cortex of awake rats in response to a single peripheral or central administration of dexfenfluramine. Brain Research 737:1-2, pages 221-230.
Crossref
Crossref
Vladimir S. Kostić, Dusica Lečić, Miroslava Doder, Jelena Marinković & Saša Filipović. (1996) Prolactin and cortisol responses to fenfluramine in Parkinson's disease. Biological Psychiatry 40:8, pages 769-775.
Crossref
Crossref
Kenneth W. Locke, Tamara R. Levesque, Katherine L. Nicholson & Robert L. Balster. (1996) Dexfenfluramine lacks amphetamine-like abuse potential. Progress in Neuro-Psychopharmacology and Biological Psychiatry 20:6, pages 1019-1035.
Crossref
Crossref
S. Salmon, C. Curradi, E. Del Bene & F. Sicuteri. 1996. Recent Advances in Tryptophan Research. Recent Advances in Tryptophan Research
97
100
.
Danuta Marona-Lewicka, Gyu-Seek Rhee, Jon E. Sprague & David E. Nichols. (1995) Psychostimulant-like effects of p-fluoroamphetamine in the rat. European Journal of Pharmacology 287:2, pages 105-113.
Crossref
Crossref
Martine Orosco, Kyriaki Gerozissis, Claude Rouch, Marie‐José Meile & Stylianos Nicolaidïs. (2012) Hypothalamic Monoamines and Insulin in Relation to Feeding in the Genetically Obese Zucker Rat as Revealed by Microdialysis. Obesity Research 3:S5.
Crossref
Crossref
Silvio Garattini. (2012) Biological Actions of Drugs Affecting Serotonin and Eating. Obesity Research 3:S4.
Crossref
Crossref
M. Orosco, C. Rough, M.J. Meile & S. Nicolaidis. (1995) Spontaneous feeding-related monoamine changes in rostromedial hypothalamus of the obese Zucker rat: A microdialysis study. Physiology & Behavior 57:6, pages 1103-1106.
Crossref
Crossref
H. G. Baumgarten & B. Zimmermann. 1992. Selective Neurotoxicity. Selective Neurotoxicity
225
291
.
Marco Gobbi, Emanuela Frittoli, Angela Uslenghi & Tiziana Mennini. (1993) Evidence of an exocytotic-like release of [3H]5-hydroxytryptamine induced by d-fenfluramine in rat hippocampal synaptosomes. European Journal of Pharmacology 238:1, pages 9-17.
Crossref
Crossref
P. Petit, Y. Sauvaire, G. Ponsin, M. Manteghetti, A. Fave & G. Ribes. (1993) Effects of a fenugreek seed extract on feeding behaviour in the rat: Metabolic-endocrine correlates. Pharmacology Biochemistry and Behavior 45:2, pages 369-374.
Crossref
Crossref
Francis Chaouloff. (1993) Effects of tianeptine on 5-HTP- and dextrofenfluramine-induced hypophagia in the rat. Pharmacology Biochemistry and Behavior 44:4, pages 989-992.
Crossref
Crossref
Uriel Halbreich & Henry Tworek. (1995) Altered Serotonergic Activity in Women with Dysphoric Premenstrual Syndromes. The International Journal of Psychiatry in Medicine 23:1, pages 1-27.
Crossref
Crossref
Silvio Caccia, Marina Anelli, Adele Ferrarese, Claudia Fracasso & Silvio Garattini. (1993) The role of d-norfenfluramine in the indole-depleting effect of d-fenfluramine in the rat. European Journal of Pharmacology 233:1, pages 71-77.
Crossref
Crossref
Silvio Caccia, Marina Anelli, Claudia Fracasso, Emanuela Frittoli, Paolo Giorcelli, Marco Gobbi, Carlo Taddei, Silvio Garattini & Tiziana Mennini. (1993) Anorectic effect and brain concentrations of D-fenfluramine in the marmoset: relationship to the in vivo and in vitro effects on serotonergic mechanisms. Naunyn-Schmiedeberg's Archives of Pharmacology 347:3, pages 306-312.
Crossref
Crossref
Francis Chaouloff. (1993) Physiopharmacological interactions between stress hormones and central serotonergic systems. Brain Research Reviews 18:1, pages 1-32.
Crossref
Crossref
M. Orosco & S. Nicolaidis. (1992) Spontaneous feeding-related monoaminergic changes in the rostromedial hypothalamus revealed by microdialysis. Physiology & Behavior 52:5, pages 1015-1019.
Crossref
Crossref
S. Caccia, S. Sarati, M. Anelli & S. Garattini. (1992) Effect of escalating doses of d-fenfluramine on the content of indoles in brain. Neuropharmacology 31:9, pages 875-879.
Crossref
Crossref
Alain M. Gardier, Seppo Kaakkola, Andreas Erfurth & Richard J. Wurtman. (1992) Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotonenergic drugs. Brain Research 588:1, pages 67-74.
Crossref
Crossref
Marianne E. Olds & Arthur Yuwiler. (1992) Effects of acute and chronic fenfluramine on self-stimulation and its facilitation by amphetamine. European Journal of Pharmacology 216:3, pages 363-372.
Crossref
Crossref
Karen E. Sabol, Jerry B. Richards & Lewis S. Seiden. (1992) The NMDA receptor antagonist MK-801 does not protect against serotonin depletions caused by high doses ofdl-fenfluramine. Brain Research 582:1, pages 129-133.
Crossref
Crossref
John W. Hubbard, Barringer D. Marshall, Nuggehally R. Srinivas, Linda L. Bowen, John K. Cooper, Robert P. Liberman & K. K. Midha. (2012) Pharmacokinetics of Fenfluramine and Neuroleptics in the Treatment of Refractory Schizophrenia. Drug Investigation 4:2, pages 99-111.
Crossref
Crossref
E. Hollander, D. J. Stein, J. B. Saoud, C. M. DeCaria, T. B. Cooper, M. N. Islam, M. R. Liebowitz & M. Stanley. (1992) Effects of fenfluramine on plasma homovanillic acid in healthy subjects. Journal of Neural Transmission 90:1, pages 81-84.
Crossref
Crossref
Reinhard W�lfel & Karl-Heinz Graefe. (1992) Evidence for various tryptamines and related compounds acting as substrates of the platelet 5-hydroxytryptamine transporter. Naunyn-Schmiedeberg's Archives of Pharmacology 345:2, pages 129-136.
Crossref
Crossref
S Garattini, A Bizzi, AM Codegoni, S Caccia & T Mennini. (1992) Progress report on the anorexia induced by drugs believed to mimic some of the effects of serotonin on the central nervous system. The American Journal of Clinical Nutrition 55:1, pages 160S-166S.
Crossref
Crossref
Karen E. Sabol, Jerry B. Richards & Lewis S. Seiden. (1992) Fenfluramine-induced increases in extracellular hippocampal serotonin are progressively attenuated in vivo during a four-day fenfluramine regimen in rats. Brain Research 571:1, pages 64-72.
Crossref
Crossref
Gary L. Brammer, Michael J. Raleigh, Edward R. Ritvo, Edward Geller, Michael T. McGuire & Arthur Yuwiler. (1991) Fenfluramine effects on serotonergic measures in vervet monkeys. Pharmacology Biochemistry and Behavior 40:2, pages 267-271.
Crossref
Crossref
Errol B. De Souza, Robert Zaczek, Steven Culp, Nathan M. Appel & Joseph F. Contrera. (1991) Comparison of the effects of repeated oral versus subcutaneous fenfluramine administration on rat brain monoamine neurons: Pharmacokinetic and dose-response data. Pharmacology Biochemistry and Behavior 39:4, pages 963-969.
Crossref
Crossref
C.S. Aulakh, J. Zohar, K.M. Wozniak, J.L. Hill, M. Haass & D.L. Murphy. (1991) Differential effects of antidepressant treatments on fenfluramine-induced increases in plasma prolactin and corticosterone in rats. Pharmacology Biochemistry and Behavior 39:1, pages 91-95.
Crossref
Crossref
M. Kalia. (1991) Reversible, short-lasting, and dose-dependent effect of (+)-fenfluramine on neocortical serotonergic axons. Brain Research 548:1-2, pages 111-125.
Crossref
Crossref
C.S. Aulakh, J. Zohar, K.M. Wozniak, J.L. Hill & D.L. Murphy. (2016) Differential effect of lithium treatment on fenfluramine-induced decreases in food intake and locomotor activity in rats. Journal of Psychopharmacology 5:2, pages 149-154.
Crossref
Crossref
Shuqin Luo & Edmund T.S. Li. (1991) Effects of repeated administration of serotonergic agonists on diet selection and body weight in rats. Pharmacology Biochemistry and Behavior 38:3, pages 495-500.
Crossref
Crossref
Constantino Sotelo. (1991) Immunohistochemical study of short- and long-term effects ofdl-fenfluramine on the serotonergic innervation of the rat hippocampal formation. Brain Research 541:2, pages 309-326.
Crossref
Crossref
A.M. Gardier & R.J. Wurtman. (1991) Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration. Brain Research 540:1-2, pages 325-330.
Crossref
Crossref
Martin D. Schechter. (1990) Functional consequences of fenfluramine neurotoxicity. Pharmacology Biochemistry and Behavior 37:4, pages 622-626.
Crossref
Crossref
C.F. Sarkissian, R.J. Wurtman, A.N. Morse & R. Gleason. (1990) Effects of fluoxetine ord-fenfluramine on serotonin release from, and levels in, rat frontal cortex. Brain Research 529:1-2, pages 294-301.
Crossref
Crossref
Paul J. Fletcher & Michael Davies. (1990) Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats. European Journal of Pharmacology 184:2-3, pages 265-271.
Crossref
Crossref
L. M. Stern, M. K. Walker, M. G. Sawyer, R. D. Oades, N. R. Badcock & J. G. Spence. (2006) A Controlled Crossover Trial of Fenfluramine in Autism. Journal of Child Psychology and Psychiatry 31:4, pages 569-585.
Crossref
Crossref
Michael Horowitz, Anne Maddox, Judith Wishart, Jane Vernon-Roberts, Barry Chatterton & David Shearman. (2007) Effect of dexfenfluramine on gastric emptying of a mixed solid-liquid meal in obese subjects. British Journal of Nutrition 63:3, pages 447-455.
Crossref
Crossref
Michael P. Johnson & David E. Nichols. (1990) Comparative serotonin neurotoxicity of the stereoisomers of fenfluramine and norfenfluramine. Pharmacology Biochemistry and Behavior 36:1, pages 105-109.
Crossref
Crossref
Jacqueline Scuvée-Moreau & Albert Dresse. (1990) Influence of fenfluramine and norfenfluramine stereoisomers on the firing rate of central monoaminergic neurons in the rat. European Journal of Pharmacology 179:1-2, pages 211-215.
Crossref
Crossref
Shlomo Sasson, Baruch Kunievsky, Christine Nathan & Erol Ceras. (1990) On the role of 5-hydroxytryptamine in the peripheral action of fenfluramine: studies with the isolated rat soleus muscle. Biochemical Pharmacology 39:5, pages 965-968.
Crossref
Crossref
V. Coiro, M. Passeri, L. Capretti, G. Speroni, C. Davoli, C. Marchesi, G. Rossi, L. Camellini, R. Volpi, E. Roti & P. Chiodera. (1990) Serotonergic control of TSH and PRL secretion in obese men. Psychoneuroendocrinology 15:4, pages 261-268.
Crossref
Crossref
Silvio Garattini & Silvio Caccia. 1990. Serotonin. Serotonin
637
643
.
F. Sicuteri, M. Poggioni & A. Panconesi. 1990. Serotonin. Serotonin
391
404
.
C. Oliver, D. Ježová, M. Grino, V. Guillaume, F. Boudouresque, B. Conte-Devolx, G. Pesce, A. Dutour & D. Becquet. 1990. Circulating Regulatory Factors and Neuroendocrine Function. Circulating Regulatory Factors and Neuroendocrine Function
427
443
.
Nathan M. Appel, Wm. Mark Mitchell, Joseph F. Contrera & Errol B. Desouza. (2004) Effects of high‐dose fenfluramine treatment on monoamine uptake sites in rat brain: Assessment using quantitative autoradiography. Synapse 6:1, pages 33-44.
Crossref
Crossref
S. Garattini, T. Mennini & R. Samanin. (2018) Reduction of Food Intake by Manipulation of Central Serotonin Current Experimental Results. British Journal of Psychiatry 155:S8, pages 41-51.
Crossref
Crossref
ROSARIO SAMANIN & SILVIO GARATTINI. (1989) Serotonin and the Pharmacology of Eating Disorders. Annals of the New York Academy of Sciences 575:1 The Psychobio, pages 194-208.
Crossref
Crossref
Mark S. Kleven & Lewis S. Seiden. (1989) D-, L- and DL-fenfluramine cause long-lasting depletions of serotonin in rat brain. Brain Research 505:2, pages 351-353.
Crossref
Crossref
J. J. López-IborJrJr, J. Saiz-Ruiz & L. Moral Iglesias. (2018) Neuroendocrine Challenges in the Diagnosis of Depressive Disorders. British Journal of Psychiatry 154:S4, pages 73-76.
Crossref
Crossref
B. Guy-Grand, M. Apfelbaum, G. Crepaldi, A. Gries, P. Lefebvre & P. Turner. (1989) Étude internationale de l'effet de la dexfenfluramine dans l'obésité (ISIS): résultats à 6 mois. La Revue de Médecine Interne 10:3, pages 271-277.
Crossref
Crossref
Michel Cabanac, Chantal Ferber & Marc Fantino. (1989) Effects of dexfenfluramine on the feeding behavior of rats foraging in the cold for palatable bait. Pharmacology Biochemistry and Behavior 32:4, pages 1025-1031.
Crossref
Crossref
Roberto Invernizzi, Claudia Fracasso, Silvio Caccia, Angelo Di Clemente, Silvio Garattini & Rosario Samanin. (1989) Effect of L-cysteine on the long-term depletion of brain indoles caused by p-chloroamphetamine and d-fenfluramine in rats Relation to brain drug concentrations. European Journal of Pharmacology 163:1, pages 77-83.
Crossref
Crossref
Judith D. Schaechter & Richard J. Wurtman. (1989) Effect of chronic d-fenfluramine administration on rat hypothalamic serotonin levels and release. Life Sciences 44:4, pages 265-271.
Crossref
Crossref
Ray W. Fuller, Harold D. Snoddy & David W. Robertson. (1988) Mechanisms of effects of d-Fenfluramine on brain serotonin metabolism in rats: Uptake inhibition versus release. Pharmacology Biochemistry and Behavior 30:3, pages 715-721.
Crossref
Crossref
Paul J. Fletcher. (1988) The effects of d-fenfluramine on saccharin intake and preference, and on food and water intake. Pharmacology Biochemistry and Behavior 29:4, pages 687-691.
Crossref
Crossref
Philip Wang, Charanjit S. Aulakh, James L. Hill & Dennis L. Murphy. (1988) Fawn hooded rats are subsensitive to the food intake suppressant effects of 5-HT agonists. Psychopharmacology 94:4, pages 558-562.
Crossref
Crossref
Claudia Fracasso, Giovanna Guiso, Silvio Garattini & Silvio Caccia. (1988) Disposition of d-fenfluramine in lean and obese rats. Appetite 10:1, pages 45-55.
Crossref
Crossref
N.R. Srinivas, J.W. Hubbard, J.K. Cooper & K.K. Midha. (1988) Enantioselective gas chromatographic assay with electron-capture detection for dl-fenfluramine and dl-norfenfluramine in plasma. Journal of Chromatography B: Biomedical Sciences and Applications 433, pages 105-117.
Crossref
Crossref
S. Garattini & T. Mennini. 1988.
259
280
.
T. Mennini, M. Gobbi, C. Taddei & S. Garattini. (1988) Characterization of high affinity and stereospecific binding to rat brain. Neurochemistry International 13:3, pages 345-351.
Crossref
Crossref
C. NATHAN & Y. ROLLAND. (2006) Pharmacological Treatments That Affect CNS Activity: Serotonin. Annals of the New York Academy of Sciences 499:1, pages 277-296.
Crossref
Crossref
SILVIO GARATTINI, TIZIANA MENNINI & ROSARIO SAMANIN. (2006) From Fenfluramine Racemate to d-Fenfluramine. Annals of the New York Academy of Sciences 499:1, pages 156-166.
Crossref
Crossref
Steven J. Cooper & Joanna C. Neill. (1987) 5-H Treceptors and the sweet tooth. Trends in Pharmacological Sciences 8:6, pages 199-200.
Crossref
Crossref
Michael F. Sugrue. (1987) Neuropharmacology of drugs affecting food intake. Pharmacology & Therapeutics 32:2, pages 145-182.
Crossref
Crossref
Arthur Yuwiler & Daniel X. Freedman. 1987. Neurobiological Issues in Autism. Neurobiological Issues in Autism
263
284
.
Gail F. Weiss, Peter Papadakos, Karen Knudson & Sarah F. Leibowitz. (1986) Medial hypothalamic serotonin: Effects on deprivation and norepinephrine-induced eating. Pharmacology Biochemistry and Behavior 25:6, pages 1223-1230.
Crossref
Crossref
Gail Shor-Posner, Joel A. Grinker, Constantine Marinescu, Owen Brown & Sarah F. Leibowitz. (1986) Hypothalamic serotonin in the control of meal patterns and macronutrient selection. Brain Research Bulletin 17:5, pages 663-671.
Crossref
Crossref
Neil E. Rowland & Janis Carlton. (1986) Effects of fenfluramine on food intake, body weight, gastric emptying and brain monoamines in syrian hamsters. Brain Research Bulletin 17:4, pages 575-581.
Crossref
Crossref
Tim C. Kirkham & John E. Blundell. (1986) Effect of naloxone and naltrexone on the development of satiation measured in the runway: Comparisons with d-amphetamine and d-fenfluramine. Pharmacology Biochemistry and Behavior 25:1, pages 123-128.
Crossref
Crossref
Martin D. Schechter. (1986) Fenfluramine discrimination in obese and lean Zucker rats: Serotonergic medaition of effect. European Journal of Pharmacology 125:1, pages 135-141.
Crossref
Crossref
Patrick Even & Stylianos Nicolaïdis. (1986) Metabolic mechanism of the anorectic and leptogenic effects of the serotonin agonist fenfluramine. Appetite 7, pages 141-163.
Crossref
Crossref
M. Fantino, F. Faion & Y. Rolland. (1986) Effect of dexfenfluramine on body weight set-point: Study in the rat with hoarding behaviour. Appetite 7, pages 115-126.
Crossref
Crossref
Neil E. Rowland & Janis Carlton. (1986) Tolerance to fenfluramine anorexia: Fact or fiction?. Appetite 7, pages 71-83.
Crossref
Crossref
S. Garattini, T. Mennini, C. Bendotti, R. Invernizzi & R. Samanin. (1986) Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system. Appetite 7, pages 15-38.
Crossref
Crossref
Thomas F. Long, Robert S. Edgecomb & Larry L. Murdock. (1986) Effects of substituted phenylethylamines on blowfly feeding behavior. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 83:1, pages 201-209.
Crossref
Crossref
Neil E. Rowland & Janis Carlton. (1986) Neurobiology of an anorectic drug: Fenfluramine. Progress in Neurobiology 27:1, pages 13-62.
Crossref
Crossref
Roberto Invernizzi, Claudio Berettera, Silvio Garattini & Rosario Samanin. (1986) D- and L-isomers of fenfluramine differ markedly in their interaction with brain serotonin and catecholamines in the rat. European Journal of Pharmacology 120:1, pages 9-15.
Crossref
Crossref
Joseph S. Soblosky, Gary DuMontier & Ingming Jeng. (2006)
Down‐Regulation of [
3
H]5‐Hydroxytryptamine Binding Sites in Chick Embryo Brain by Monoamine Oxidase Inhibitors or Fenfluramine and Potentiation by
d,l
‐5‐Hydroxytryptophan
. Journal of Neurochemistry 45:6, pages 1923-1931.
Crossref
Crossref
P.L. Thurlby, S. Garattini & R. Samanin. (1985) Effects of serotonin antagonists on the performance of a simple food acquisition task in rats treated with fenfluramine isomers. Pharmacological Research Communications 17:12, pages 1129-1139.
Crossref
Crossref
Martin D. Schechter & Judith A. Finkelstein. (1985) Effect of dopamine agonists and fenfluramine on discriminative behavior in obese and lean Zucker rats. Pharmacology Biochemistry and Behavior 23:1, pages 7-11.
Crossref
Crossref
L.D. Van de Kar, K.D. Richardson & J.H. Urban. (1985) Serotonin and norepinephrine-dependent effects of fenfluramine on plasma renin activity in conscious male rats. Neuropharmacology 24:6, pages 487-494.
Crossref
Crossref
David N. Brindley, Janice Saxton, Hossain Shahidullah & Margaret Armstrong. (1985) Possible relationships between changes in body weight set-point and stress metabolism after treating rats chronically with d-fenfluramine. Biochemical Pharmacology 34:8, pages 1265-1271.
Crossref
Crossref
S. Caccia, I. Conforti, J. Duchier & S. Garattini. (1985) Pharmacokinetics of fenfluramine and norfenfluramine in volunteers given d- and dl-fenfluramine for 15 days. European Journal of Clinical Pharmacology 29:2, pages 221-224.
Crossref
Crossref
Tiziana Mennini, Silvio Garattini & Silvio Caccia. (1985) Anorectic effect of fenfluramine isomers and metabolites: Relationship between brain levels and in vitro potencies on serotonergic mechanisms. Psychopharmacology 85:1, pages 111-114.
Crossref
Crossref
E. A. Mueller, L. J. Siever & D. L. Murphy. 1985. Pathochemical Markers in Major Psychoses. Pathochemical Markers in Major Psychoses
110
128
.
Neil Rowland & Janis Carlton. (1984) Inhibition of gastric emptying by peripheral and central fenfluramine in rats: Correlation with anorexia. Life Sciences 34:25, pages 2495-2499.
Crossref
Crossref
U. Spampinato, E. Nowakowska & R. Samanin. (1984) Effects of agents increasing serotonin transmission on the increase of dopamine metabolism caused by morphine in the rat nucleus accumbens. Pharmacological Research Communications 16:5, pages 513-517.
Crossref
Crossref
Janis Carlton & Neil Rowland. (1984) Anorexia and brain serotonin: Development of tolerance to the effects of fenfluramine and quipazine in rats with serotonin-depleting lesions. Pharmacology Biochemistry and Behavior 20:5, pages 739-745.
Crossref
Crossref
R.H. Rech, F. Borsini & R. Samanin. (1984) Effects of d-amphetamine and d-fenfluramine on performance of rats in a food maze. Pharmacology Biochemistry and Behavior 20:4, pages 489-493.
Crossref
Crossref
U. Spampinato, R. Invernizzi, E. Nowakowska & R. Samanin. (1984) Reduction of morphine's effect on striatal dopamine metabolism in rats treated with a low dose of apomorphine or agents increasing serotonin transmission. Biochemical Pharmacology 33:1, pages 163-165.
Crossref
Crossref
Franco Borsini, Caterina Bendotti, Barbara Przewlocka & Rosario Samanin. (1983) Monoamine involvement in the overeating caused by muscimol injection in the rat nucleus raphe dorsalis and the effects of d-fenfluramine and d-amphetamine. European Journal of Pharmacology 94:1-2, pages 109-115.
Crossref
Crossref
Caterina Bendotti, Franco Borsini & Rosario Samanin. (1983) Studies on the mechanisms of tolerance to the anorectic effect of salbutamol in rats. European Journal of Pharmacology 92:3-4, pages 237-242.
Crossref
Crossref
Neil Rowland & Janis Carlton. (1983) Different behavioral mechanisms underlie tolerance to the anorectic effects of fenfluramine and quipazine. Psychopharmacology 81:2, pages 155-157.
Crossref
Crossref
E. Borroni, A. Ceci, S. Garattini & T. Mennini. (1983) Differences Between d-Fenfluramine and d-Norfenfluramine in Serotonin Presynaptic Mechanisms. Journal of Neurochemistry 40:3, pages 891-893.
Crossref
Crossref
F. Borsini, C. Bendotti, A. Aleotti, R. Samanin & S. Garattini. (1982) D-fenfluramine and d-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain. Pharmacological Research Communications 14:7, pages 671-678.
Crossref
Crossref
Neil Rowland, Seymour M. Antelman & Donna Kocan. (1982) Differences among ‘serotonergic’ anorectics in a cross-tolerance paradigm: Do they all act on serotonin systems?. European Journal of Pharmacology 81:1, pages 57-66.
Crossref
Crossref
R. INVERNIZZI, K. KMIECIAK‐KOLADA & R. SAMANIN. (2012) IS RECEPTOR ACTIVATION INVOLVED IN THE MECHANISM BY WHICH (+)‐FENFLURAMINE AND (+)‐NORFENFLURAMINE DEPLETE 5‐HYDROXYTRYPTAMINE IN THE RAT BRAIN?. British Journal of Pharmacology 75:3, pages 525-530.
Crossref
Crossref
C. Rochat, L. Cervo, S. Romandini & R. Samanin. (1982) Differences in the effects of d-fenfluramine and morphine on various responses of rats to painful stimuli. Psychopharmacology 76:2, pages 188-192.
Crossref
Crossref
S. Caccia, G. Dagnino, S. Garattini, G. Guiso, R. Madonna & M. G. Zanini. (1981) Kinetics of fenfluramine isomers in the rat. European Journal of Drug Metabolism and Pharmacokinetics 6:4, pages 297-301.
Crossref
Crossref
R. Samanin. 1981. Medicinal Chemistry Advances. Medicinal Chemistry Advances
271
282
.
T. Mennini, E. Borroni, R. Samanin & S. Garattini. (1981) Evidence of the existence of two different intraneuronal pools from which pharmacological agents can release serotonin. Neurochemistry International 3:5, pages 289-294.
Crossref
Crossref
S. Garattini & R. Samanin. 1981. Psychotropic Agents. Psychotropic Agents
545
586
.
V. Crunelli, S. Bernasconi & R. Samanin. (1980) Effects of d- and l-fenfluramine on striatal homovanillic acid concentrations in rats after pharmacological manipulation of brain serotonin. Pharmacological Research Communications 12:3, pages 215-223.
Crossref
Crossref
Ann C. Sullivan, Herman W. Baruth & Lorraine Cheng. 1980.
172
181
.
V. Crunelli, S. Bernasconi & R. Samanin. (1979) Evidence against serotonin involvement in the tonic component of electrically induced convulsions and in carbamazepine anticonvulsant activity. Psychopharmacology 66:1, pages 79-85.
Crossref
Crossref
S. Garattini & S. Caccia. (1979) Comparison of the plasma levels of fenfluramine in rats after a toxic dose and in man after a maximal therapeutic dose. Toxicology Letters 3:5, pages 285-290.
Crossref
Crossref