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Hazel J Dyke. (2007) Novel 5,6-dihydropyrazolo-[3,4-E][1,4]diazepin-4 (1H)-one derivatives for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opinion on Therapeutic Patents 17:9, pages 1183-1189.
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Donald J. AbrahamJohn G. Montana, Hazel J. Dyke, J. Craig Fox & Nicholas C. Ray. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery
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George Muller & Jeffrey Mckenna. 2006. Cyclic Nucleotide Phosphodiesterases in Health and Disease. Cyclic Nucleotide Phosphodiesterases in Health and Disease.
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Kai WANG, Hua-hao SHEN, Jun-chun CHEN & Zhong CHEN. (2005) Inhibitory effect of acetamide-45 on airway inflammation and phosphodiesterase 4 in allergic rats1. Acta Pharmacologica Sinica 26:12, pages 1492-1496.
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Thomas Haack, Raimondo Fattori, Mauro Napoletano, Franco Pellacini, Giovanni Fronza, Giuseppina Raffaini & Fabio Ganazzoli. (2005) Phthalazine PDE IV inhibitors: Conformational study of some 6-methoxy-1,4-disubstituted derivatives. Bioorganic & Medicinal Chemistry 13:14, pages 4425-4433.
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Hui-Fang Tang, Yan-Hua Song, Jun-Chun Chen, Ji-Qiang Chen & Peng Wang. (2005) Upregulation of Phosphodiesterase-4 in the Lung of Allergic Rats. American Journal of Respiratory and Critical Care Medicine 171:8, pages 823-828.
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Hiroshi Ochiai, Tazumi Ohtani, Akiharu Ishida, Katuya Kishikawa, Susumu Yamamoto, Hiroshi Takeda, Takaaki Obata, Hisao Nakai & Masaaki Toda. (2004) Orally active PDE4 inhibitor with therapeutic potential. European Journal of Medicinal Chemistry 39:7, pages 555-571.
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Hiroshi Ochiai, Tazumi Ohtani, Akiharu Ishida, Katuya Kishikawa, Takaaki Obata, Hisao Nakai & Masaaki Toda. (2004) Orally active PDE4 inhibitors with therapeutic potential. Bioorganic & Medicinal Chemistry Letters 14:5, pages 1323-1327.
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Domenico Spina. (2003) Phosphodiesterase-4 Inhibitors in the Treatment of Inflammatory Lung Disease. Drugs 63:23, pages 2575-2594.
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