Citations (19)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Yang Yang, Shu An, Ying Liu, Xiao-Xi Guo, Linghuan Gao, Ji-Fu Wei & Tian-Rui Xu. (2016) Novel serotonin receptor 2 (5-HT2R) agonists and antagonists: a patent review (2004-2014). Expert Opinion on Therapeutic Patents 26:1, pages 89-106.
Read now
Read now
Junwon Lee, Myung Eun Jung & Jinhwa Lee. (2010) 5-HT2C receptor modulators: a patent survey. Expert Opinion on Therapeutic Patents 20:11, pages 1429-1455.
Read now
Read now
Brian M Smith, William J Thomsen & Andrew J Grottick. (2006) The potential use of selective 5-HT2C agonists in treating obesity. Expert Opinion on Investigational Drugs 15:3, pages 257-266.
Read now
Read now
Articles from other publishers (16)
Navnit Prajapati, Rajani Giridhar, Anshuman Sinha, Ashish M. Kanhed & Mange Ram Yadav. (2015) Regioselective alkylation of 1,3,4,5-tetrahydrobenzo[d]azepin-2-one and biological evaluation of the resulting alkylated products as potentially selective $$\hbox {5-HT}_{\mathrm{2C}}$$ 5-HT 2 C agonists. Molecular Diversity 19:4, pages 653-667.
Crossref
Crossref
R. Ian Storer, Paul E. Brennan, Alan D. Brown, Peter J. Bungay, Kelly M. Conlon, Matthew S. Corbett, Robert P. DePianta, Paul V. Fish, Alexander Heifetz, Danny K. H. Ho, Alan S. Jessiman, Gordon McMurray, Cesar Augusto F. de Oliveira, Lee R. Roberts, James A. Root, Veerabahu Shanmugasundaram, Michael J. Shapiro, Melanie Skerten, Dominique Westbrook, Simon Wheeler, Gavin A. Whitlock & John Wright. (2014)
Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5-
d
]azepines as Potent 5-Hydroxytryptamine 2C (5-HT
2C
) Receptor Agonists with Exquisite Functional Selectivity over 5-HT
2A
and 5-HT
2B
Receptors
. Journal of Medicinal Chemistry 57:12, pages 5258-5269.
Crossref
Crossref
Guohua Zhao, Chet Kwon, Sharon N. Bisaha, Philip D. Stein, Karen A. Rossi, Xueying Cao, Thao Ung, Ginger Wu, Chen-Pin Hung, Sarah E. Malmstrom, Ge Zhang, Qinling Qu, Jinping Gan, William J. Keim, Mary Jane Cullen, Kenneth W. Rohrbach, James Devenny, Mary Ann Pelleymounter, Keith J. Miller & Jeffrey A. Robl. (2013) Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT2C receptor agonists. Bioorganic & Medicinal Chemistry Letters 23:13, pages 3914-3919.
Crossref
Crossref
Suman K. Vodnala, Thomas Lundbäck, Birger Sjöberg, Richard Svensson, Martin E. Rottenberg & Lars G. J. Hammarström. (2013)
In Vitro
and
In Vivo
Activities of 2-Aminopyrazines and 2-Aminopyridines in Experimental Models of Human African Trypanosomiasis
. Antimicrobial Agents and Chemotherapy 57:2, pages 1012-1018.
Crossref
Crossref
Pooja S. Banerjee & P. K. Sharma. (2011) New antiepileptic agents: structure–activity relationships. Medicinal Chemistry Research 21:7, pages 1491-1508.
Crossref
Crossref
Kathryn M. Hurren & Helen D. Berlie. (2011) Lorcaserin: An investigational serotonin 2C agonist for weight loss. American Journal of Health-System Pharmacy 68:21, pages 2029-2037.
Crossref
Crossref
Mark D. Andrews, Paul V. Fish, Julian Blagg, Tiffini K. Brabham, Paul E. Brennan, Alison Bridgeland, Alan D. Brown, Peter J. Bungay, Kelly M. Conlon, Nicholas J. Edmunds, Kerry af Forselles, Colleen P. Gibbons, Martin P. Green, Giles Hanton, Mark Holbrook, Alan S. Jessiman, Karin McIntosh, Gordon McMurray, Carly L. Nichols, James A. Root, R. Ian Storer, Michael R. Sutton, Robin V. Ward, Dominique Westbrook & Gavin A. Whitlock. (2011) Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence. Bioorganic & Medicinal Chemistry Letters 21:9, pages 2715-2720.
Crossref
Crossref
Charlotte M.N. Allerton, Mark D. Andrews, Julian Blagg, David Ellis, Edel Evrard, Martin P. Green, Kevin K.-C. Liu, Gordon McMurray, Michael Ralph, Vivienne Sanderson, Robin Ward & Lesa Watson. (2009) Design and synthesis of pyridazinone-based 5-HT2C agonists. Bioorganic & Medicinal Chemistry Letters 19:19, pages 5791-5795.
Crossref
Crossref
Mark D. Andrews, Martin P. Green, Charlotte M.N. Allerton, David V. Batchelor, Julian Blagg, Alan D. Brown, David W. Gordon, Gordon McMurray, Daniel J. Millns, Carly L. Nichols & Lesa Watson. (2009) Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT2C agonists. Bioorganic & Medicinal Chemistry Letters 19:18, pages 5346-5350.
Crossref
Crossref
Paul V. Fish, Alan D. Brown, Edel Evrard & Lee R. Roberts. (2009) 7-Sulfonamido-3-benzazepines as potent and selective 5-HT2C receptor agonists: Hit-to-lead optimization. Bioorganic & Medicinal Chemistry Letters 19:7, pages 1871-1875.
Crossref
Crossref
Bayard R. Huck, Luis Llamas, Michael J. Robarge, Thomas C. Dent, Jianping Song, William F. Hodnick, Chris Crumrine, Alain Stricker-Krongrad, John Harrington, Kurt R. Brunden & Youssef L. Bennani. (2006) The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist. Bioorganic & Medicinal Chemistry Letters 16:15, pages 4130-4134.
Crossref
Crossref
Björn M. Nilsson. (2006)
5-Hydroxytryptamine 2C (5-HT
2C
) Receptor Agonists as Potential Antiobesity Agents
. Journal of Medicinal Chemistry 49:14, pages 4023-4034.
Crossref
Crossref
Bayard R. Huck, Luis Llamas, Michael J. Robarge, Thomas C. Dent, Jianping Song, William F. Hodnick, Chris Crumrine, Alain Stricker-Krongrad, John Harrington, Kurt R. Brunden & Youssef L. Bennani. (2006) The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists. Bioorganic & Medicinal Chemistry Letters 16:11, pages 2891-2894.
Crossref
Crossref
Bruce N. Rogers & Christopher J. Schmidt. 2006. Annual Reports in Medicinal Chemistry Volume 41. Annual Reports in Medicinal Chemistry Volume 41
3
21
.
Wayne E. Childers,Jr.Jr. & Albert J. Robichaud. 2005. Annual Reports in Medicinal Chemistry Volume 40. Annual Reports in Medicinal Chemistry Volume 40
17
33
.
Xu-Feng Huang, Mei Han & Len H Storlien. (2004) Differential expression of 5-HT2A and 5-HT2C receptor mRNAs in mice prone, or resistant, to chronic high-fat diet-induced obesity. Molecular Brain Research 127:1-2, pages 39-47.
Crossref
Crossref