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Review

Novel microsomal triglyceride transfer protein inhibitors

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Pages 479-488 | Published online: 02 Mar 2005

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Keith E Suckling. (2006) The return of two old targets?. Expert Opinion on Therapeutic Targets 10:6, pages 785-788.
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Ralph P. Robinson, Jeremy A. Bartlett, Peter Bertinato, Andrew J. Bessire, Judith Cosgrove, Patrick M. Foley, Tara B. Manion, Martha L. Minich, Brenda Ramos, Matthew R. Reese, Theodore J. Schmahai, Andrew G. Swick, David A. Tess, Alfin Vaz & Angela Wolford. (2011) Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide. Bioorganic & Medicinal Chemistry Letters 21:14, pages 4150-4154.
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Chi B. Vu, Jill C. Milne, David P. Carney, Jeffrey Song, Wendy Choy, Philip D. Lambert, David J. Gagne, Michael Hirsch, Angela Cote, Meghan Davis, Elden Lainez, Nekeya Meade, Karl Normington, Michael R. Jirousek & Robert B. Perni. (2009) Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors. Bioorganic & Medicinal Chemistry Letters 19:5, pages 1416-1420.
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D. A. MERRITT, A. J. BESSIRE, A. D. VAZ, J. P. SAMS & M. P. LYNCH. (2007) Absorption, distribution, metabolism, and excretion of dirlotapide in the dog. Journal of Veterinary Pharmacology and Therapeutics 30:s1, pages 17-23.
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J. A. WREN, J. GOSSELLIN & S. J. SUNDERLAND. (2007) Dirlotapide: a review of its properties and role in the management of obesity in dogs. Journal of Veterinary Pharmacology and Therapeutics 30:s1, pages 11-16.
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D. A. MERRITT, M. P. LYNCH & V. L. KING. (2007) Pharmacokinetics of dirlotapide in the dog. Journal of Veterinary Pharmacology and Therapeutics 30:s1, pages 24-32.
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