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Expert Opinion on Therapeutic Patents Volume 15, 2005 - Issue 6
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Review

Cyclin-dependent kinase inhibitors: a survey of the recent patent literature

Paolo Pevarello Department of Chemistry, BU-Oncology, Nerviano Medical Sciences, Viale Pasteur, 10, 20014 Nerviano (MI), Italy. [email protected]
&
Manuela Villa Department of Chemistry, BU-Oncology, Nerviano Medical Sciences, Viale Pasteur, 10, 20014 Nerviano (MI), Italy. [email protected]
Pages 675-703 | Published online: 14 Jun 2005

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Hervé Galons, Nassima Oumata, Olfa Gloulou & Laurent Meijer. (2013) Cyclin-dependent kinase inhibitors closer to market launch?. Expert Opinion on Therapeutic Patents 23:8, pages 945-963.
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PKS Sarma, Ruchi Tandon, Praful Gupta, Sunanda G Dastidar, Abhijit Ray, Biswajit Das & Ian A Cliffe. (2007) Progress in the development of small molecule inhibitors of insulin-like growth factor-1 receptor kinase. Expert Opinion on Therapeutic Patents 17:1, pages 25-35.
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Articles from other publishers (11)

Nishtha Malhotra, Rohan Gupta & Pravir Kumar. (2021) Pharmacological relevance of CDK inhibitors in Alzheimer's disease. Neurochemistry International 148, pages 105115.
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Abdel-Sattar S. Hamad Elgazwy, Nasser S.M. Ismail & Heba S.A. Elzahabi. (2010) A convenient synthesis and molecular modeling study of novel purine and pyrimidine derivatives as CDK2/cyclin A3 inhibitors. Bioorganic & Medicinal Chemistry 18:21, pages 7639-7650.
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Søren M. Johnson, Chad D. Torrice, Jessica F. Bell, Kimberly B. Monahan, Qi Jiang, Yong Wang, Matthew R. Ramsey, Jian Jin, Kwok-Kin Wong, Lishan Su, Daohong Zhou & Norman E. Sharpless. (2010) Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. Journal of Clinical Investigation 120:7, pages 2528-2536.
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Rosa M. Claramunt, Dionisia Sanz, Concepción López, Elena Pinilla, M. Rosario Torres, José Elguero, Pierre Nioche & C. S. Raman. (2009) The Structures of Indazolin‐3‐one (=1,2‐Dihydro‐3 H ‐indazol‐3‐one) and 7‐Nitroindazolin‐3‐one . Helvetica Chimica Acta 92:10, pages 1952-1962.
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Paul G. Wyatt, Andrew J. Woodhead, Valerio Berdini, John A. Boulstridge, Maria G. Carr, David M. Cross, Deborah J. Davis, Lindsay A. Devine, Theresa R. Early, Ruth E. Feltell, E. Jonathan Lewis, Rachel L. McMenamin, Eva F. Navarro, Michael A. O’Brien, Marc O’Reilly, Matthias Reule, Gordon Saxty, Lisa C. A. Seavers, Donna-Michelle Smith, Matt S. Squires, Gary Trewartha, Margaret T. Walker & Alison J.-A. Woolford. (2008) Identification of N -(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1 H -pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design . Journal of Medicinal Chemistry 51:16, pages 4986-4999.
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Shuchun Guo, Yanfang Zhao, Xianglin Zhao, Sisi Zhang, Lijun Xie, Weiyong Kong & Ping Gong. (2007) Synthesis and Anti‐tumor Activities of Novel Methylthio‐, Sulfinyl‐, and Sulfonyl‐8 H ‐thieno[2,3‐ b ]pyrrolizin‐8‐oximino Derivatives . Archiv der Pharmazie 340:8, pages 416-423.
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Shaoqing Chen, Li Chen, Nam T. Le, Chunlin Zhao, Achyutharao Sidduri, Jian Ping Lou, Christophe Michoud, Louis Portland, Nicole Jackson, Jin-Jun Liu, Fred Konzelmann, Feng Chi, Christian Tovar, Qing Xiang, Yingsi Chen, Yang Wen & Lyubomir T. Vassilev. (2007) Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors. Bioorganic & Medicinal Chemistry Letters 17:8, pages 2134-2138.
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Kevin J. Moriarty, Holly Koblish, Dana L. Johnson & Robert A. GalemmoJrJr. 2007. Cancer. Cancer 207 291 .
Xin-Jie Chu, Wanda DePinto, David Bartkovitz, Sung-Sau So, Binh T. Vu, Kathryn Packman, Christine Lukacs, Qingjie Ding, Nan Jiang, Ka Wang, Petra Goelzer, Xuefeng Yin, Melissa A. Smith, Brian X. Higgins, Yingsi Chen, Qing Xiang, John Moliterni, Gerald Kaplan, Bradford Graves, Allen Lovey & Nader Fotouhi. (2006) Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), A Potent and Selective Cyclin-Dependent Kinase Inhibitor with Significant in Vivo Antitumor Activity. Journal of Medicinal Chemistry 49:22, pages 6549-6560.
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Roberto Martínez, J. Gustavo Ávila, Ma. Teresa Ramírez, Araceli Pérez & Ángeles Martínez. (2006) Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds. Bioorganic & Medicinal Chemistry 14:12, pages 4007-4016.
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Kate F. Byth, Catherine Geh, Cheryl L. Forder, Sandra E. Oakes & Andrew P. Thomas. (2006) The cellular phenotype of AZ703, a novel selective imidazo[1,2- a ]pyridine cyclin-dependent kinase inhibitor . Molecular Cancer Therapeutics 5:3, pages 655-664.
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