Citations (10)
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Mathieu RappasAmmar A. E. AliKirstie A. BennettJason D. BrownSarah J. BucknellMiles Congreve, Robert M. CookeGabriella CsekeChris de GraafAndrew S. DoréJames C. ErreyAli JazayeriFiona H. MarshallJonathan S. MasonRichard MouldJayesh C. PatelBenjamin G. TehanMalcolm WeirJohn A. Christopher. (2019) Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis. Journal of Medicinal Chemistry 63:4, pages 1528-1543.
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Bibia Heidmann, John Gatfield, Catherine Roch, Alexander Treiber, Simone Tortoioli, Christine Brotschi, Jodi T. Williams, Martin H. Bolli, Stefan Abele, Thierry Sifferlen, François Jenck & Christoph Boss. (2016) Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold-Hopping Approach. ChemMedChem 11:19, pages 2132-2146.
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Rong Jiang, Xinyi Song, Purva Bali, Anthony Smith, Claudia Ruiz Bayona, Li Lin, Michael D. Cameron, Patricia H. McDonald, Paul J. Kenny & Theodore M. Kamenecka. (2012) Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists. Bioorganic & Medicinal Chemistry Letters 22:12, pages 3890-3894.
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Christopher D. Cox, Michael J. Breslin, David B. Whitman, John D. Schreier, Georgia B. McGaughey, Michael J. Bogusky, Anthony J. Roecker, Swati P. Mercer, Rodney A. Bednar, Wei Lemaire, Joseph G. Bruno, Duane R. Reiss, C. Meacham Harrell, Kathy L. Murphy, Susan L. Garson, Scott M. Doran, Thomayant Prueksaritanont, Wayne B. Anderson, Cuyue Tang, Shane Roller, Tamara D. Cabalu, Donghui Cui, George D. Hartman, Steven D. Young, Ken S. Koblan, Christopher J. Winrow, John J. Renger & Paul J. Coleman. (2010)
Discovery of the Dual Orexin Receptor Antagonist [(7
R
)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2
H
-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the Treatment of Insomnia
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Akira Terao & Masaomi Miyamoto. (2007) Recent and potential drugs for treatment of insomnia. Folia Pharmacologica Japonica 129:1, pages 35-41.
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