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New antibiotics for selective treatment of gastrointestinal infection caused by Clostridium difficile

Pages 1389-1399 | Published online: 11 Aug 2010

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Mario Zucca, Sara Scutera & Dianella Savoia. (2013) Novel avenues for Clostridium difficile infection drug discovery. Expert Opinion on Drug Discovery 8:4, pages 459-477.
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A. I. Bamber, K. Fitzsimmons, J. G. Cunniffe, C. C. Beasor, C. A. Mackintosh & G. Hobbs. (2012) Diagnosis of Clostridium difficile-associated disease: examination of multiple algorithms using toxin EIA, glutamate dehydrogenase EIA and loop-mediated isothermal amplification. British Journal of Biomedical Science 69:3, pages 112-118.
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Articles from other publishers (12)

Muni Kumar Mahadari, Sreenu Jennepalli, Andrew J. Tague, Papanin Putsathit, Melanie L. Hutton, Katherine A. Hammer, Daniel R. Knight, Thomas V. Riley, Dena Lyras, Paul A. Keller & Stephen G. Pyne. (2021) Cationic Peptidomimetic Amphiphiles Having a N-Aryl- or N-Naphthyl-1,2,3-Triazole Core Structure Targeting Clostridioides (Clostridium) difficile: Synthesis, Antibacterial Evaluation, and an In Vivo C. difficile Infection Model. Antibiotics 10:8, pages 913.
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Andrew J. Tague, Papanin Putsathit, Melanie L. Hutton, Katherine A. Hammer, Steven M. Wales, Daniel R. Knight, Thomas V. Riley, Dena Lyras, Paul A. Keller & Stephen G. Pyne. (2019) Cationic biaryl 1,2,3-triazolyl peptidomimetic amphiphiles targeting Clostridioides (Clostridium) difficile: Synthesis, antibacterial evaluation and an in vivo C. difficile infection model. European Journal of Medicinal Chemistry 170, pages 203-224.
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Michael J. Aldape, Aaron E. PackhamDustin D. HeeneySavannah N. Rice, Amy E. Bryant & Dennis L. Stevens. (2017) Fidaxomicin reduces early toxin A and B production and sporulation in Clostridium difficile in vitro. Journal of Medical Microbiology 66:10, pages 1393-1399.
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Shi-Hui Dong, Weixin Tang, Tiit Lukk, Yi Yu, Satish K Nair & Wilfred A van der Donk. (2015) The enterococcal cytolysin synthetase has an unanticipated lipid kinase fold. eLife 4.
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Lynn Miesel, David W. Hecht, James R. Osmolski, Dale Gerding, Amy Flattery, Fangbiao Li, Jing Lan, Philip Lipari, Jon D. Polishook, Lianzhu Liang, Jenny Liu, David B. Olsen & Sheo B. Singh. (2014) Kibdelomycin Is a Potent and Selective Agent against Toxigenic Clostridium difficile. Antimicrobial Agents and Chemotherapy 58:4, pages 2387-2392.
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Cristina de Souza Mendes & Adelaide de Souza Antunes. (2013) Pipeline of Known Chemical Classes of Antibiotics. Antibiotics 2:4, pages 500-534.
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Carmela T. M. Mascio, Lawrence I. Mortin, Karen T. Howland, Andrew D. G. Van Praagh, Shuxin Zhang, Anu Arya, Cun Lan Chuong, Chunfeng Kang, Tongchuan Li & Jared A. Silverman. (2012) In Vitro and In Vivo Characterization of CB-183,315, a Novel Lipopeptide Antibiotic for Treatment of Clostridium difficile . Antimicrobial Agents and Chemotherapy 56:10, pages 5023-5030.
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Vicki R. Kee. (2012) Clostridium Difficile Infection in Older Adults: A Review and Update on Its Management. The American Journal of Geriatric Pharmacotherapy 10:1, pages 14-24.
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Jason W. Lancaster & S. James Matthews. (2012) Fidaxomicin: The Newest Addition to the Armamentarium Against Clostridium difficile Infections. Clinical Therapeutics 34:1, pages 1-13.
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Daniela Jabes. (2011) The antibiotic R&D pipeline: an update. Current Opinion in Microbiology 14:5, pages 564-569.
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Mark S Butler & Matthew A Cooper. (2011) Antibiotics in the clinical pipeline in 2011. The Journal of Antibiotics 64:6, pages 413-425.
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Caoilfhionn OʼDonoghue & Lorraine Kyne. (2011) Update on Clostridium difficile infection. Current Opinion in Gastroenterology 27:1, pages 38-47.
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