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Vitamin D receptor ligands: the impact of crystal structures

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Pages 417-435 | Published online: 27 Mar 2012

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Miguel A. Maestro, Ferdinand Molnár, Antonio Mouriño & Carsten Carlberg. (2016) Vitamin D receptor 2016: novel ligands and structural insights. Expert Opinion on Therapeutic Patents 26:11, pages 1291-1306.
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Ichiro Takada & Makoto Makishima. (2015) Therapeutic application of vitamin D receptor ligands: an updated patent review. Expert Opinion on Therapeutic Patents 25:12, pages 1373-1383.
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Xiaomu Tan, Lifang Gao, Xiaxia Cai, Mingyuan Zhang, Dongxu Huang, Qinyu Dang & Lei Bao. (2021) Vitamin D 3 alleviates cognitive impairment through regulating inflammatory stress in db/db mice . Food Science & Nutrition 9:9, pages 4803-4814.
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Miguel A. Maestro, Ferdinand Molnár & Carsten Carlberg. (2019) Vitamin D and Its Synthetic Analogs. Journal of Medicinal Chemistry 62:15, pages 6854-6875.
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Diego J. Obiol, Andrea Martínez, María J. Ferronato, Mario A. Quevedo, Silvina M. Grioli, Eliana N. Alonso, Generosa Gómez, Yagamare Fall, María M. Facchinetti & Alejandro C. Curino. (2019) Novel calcitriol analogue with an oxolane group: In vitro, in vivo, and in silico studies. Archiv der Pharmazie 352:5, pages 1800315.
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Adrian Fabisiak, Pawel Brzeminski, Klaudia Berkowska, Ewa Marcinkowska & Rafal R. Sicinski. (2019) Synthesis of 19-norcalcitriol analogs with pegylated alkylidene chains at C-2. The Journal of Steroid Biochemistry and Molecular Biology 185, pages 251-255.
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Rita Sigüeiro, Miguel A. Maestro & Antonio Mouriño. (2018) Synthesis of Side-Chain Locked Analogs of 1α,25-Dihydroxyvitamin D 3 Bearing a C17 Methyl Group . Organic Letters 20:9, pages 2641-2644.
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Anna Y. Belorusova & Natacha Rochel. 2016. Vitamin D Hormone. Vitamin D Hormone 83 116 .
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Maura Malinska, Andrzej Kutner & Krzysztof Wo?niak. (2015) Predicted structures of new Vitamin D Receptor agonists based on available X-ray structures. Steroids 104, pages 220-229.
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Carsten CarlbergFerdinand Molnár. (2015) Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view. Canadian Journal of Physiology and Pharmacology 93:5, pages 311-318.
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Takashi Misawa, Yosuke Demizu, Megumi Kawamura, Nanako Yamagata & Masaaki Kurihara. (2015) Structural development of stapled short helical peptides as vitamin D receptor (VDR)?coactivator interaction inhibitors. Bioorganic & Medicinal Chemistry 23:5, pages 1055-1061.
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Katarzyna Sokolowska, Diego Carballa, Samuel Seoane, Román Pérez-Fernández, Antonio Mouriño & Rafal R. Sicinski. (2014) Synthesis and Biological Activity of Two C-7 Methyl Analogues of Vitamin D. The Journal of Organic Chemistry 80:1, pages 165-173.
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Anna Y. Belorusova, Jérôme Eberhardt, Noëlle Potier, Roland H. Stote, Annick Dejaegere & Natacha Rochel. (2014) Structural Insights into the Molecular Mechanism of Vitamin D Receptor Activation by Lithocholic Acid Involving a New Mode of Ligand Recognition. Journal of Medicinal Chemistry 57:11, pages 4710-4719.
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Ferdinand Molnár. (2014) Structural considerations of vitamin D signaling. Frontiers in Physiology 5.
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René Huber, Daniel Pietsch, Johannes Günther, Bastian Welz, Nico Vogt & Korbinian Brand. (2013) Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks. Cellular and Molecular Life Sciences 71:1, pages 63-92.
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Albert M. DeBerardinis, Steven Lemieux & M. Kyle Hadden. (2013) Analogues of the Inhoffen–Lythgoe diol with anti-proliferative activity. Bioorganic & Medicinal Chemistry Letters 23:19, pages 5367-5370.
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Yosuke Demizu, Saori Nagoya, Manami Shirakawa, Megumi Kawamura, Nanako Yamagata, Yukiko Sato, Mitsunobu Doi & Masaaki Kurihara. (2013) Development of stapled short helical peptides capable of inhibiting vitamin D receptor (VDR)?coactivator interactions. Bioorganic & Medicinal Chemistry Letters 23:15, pages 4292-4296.
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Premchendar Nandhikonda, Adam Yasgar, Athena M. Baranowski, Preetpal S. Sidhu, Megan M. McCallum, Alan J. Pawlak, Kelly Teske, Belaynesh Feleke, Nina Y. Yuan, Chinedum Kevin, Daniel D. Bikle, Steven D. Ayers, Paul Webb, Ganesha Rai, Anton Simeonov, Ajit Jadhav, David Maloney & Leggy A. Arnold. (2013) Peroxisome Proliferation-Activated Receptor δ Agonist GW0742 Interacts Weakly with Multiple Nuclear Receptors, Including the Vitamin D Receptor. Biochemistry 52:24, pages 4193-4203.
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Baojian Wu, Sha Li & Dong Dong. (2013) 3D structures and ligand specificities of nuclear xenobiotic receptors CAR, PXR and VDR. Drug Discovery Today 18:11-12, pages 574-581.
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Lisa Asano, Ichiaki Ito, Naoyuki Kuwabara, Tsuyoshi Waku, Junn Yanagisawa, Hiroyuki Miyachi & Toshiyuki Shimizu. (2013) Structural basis for vitamin D receptor agonism by novel non‐secosteroidal ligands. FEBS Letters 587:7, pages 957-963.
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Diego M. Carballa, Antonio Rumbo, Mercedes Torneiro, Miguel Maestro & Antonio Mouriño. (2012) Synthesis of (1 α )‐1,25‐Dihydroxyvitamin D 3 with a β ‐Positioned Seven‐Carbon Side Chain at C(12) . Helvetica Chimica Acta 95:10, pages 1842-1850.
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