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Patent Evaluation

Evaluation of WO2012003387, Gilead's ASK1 inhibitors

, MBA, PhD
Pages 455-459 | Published online: 23 Mar 2012

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Michael P Bova & Gene G Kinney. (2013) Emerging drug targets in amyotrophic lateral sclerosis. Expert Opinion on Orphan Drugs 1:1, pages 5-20.
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Yayu Xie, Pei Cao, Yuan Qin, Xiru Wu, Bingyao Huang, Kai Liu & Yonghong Liu. (2022) Catalytic activity in vitro of the human protein kinase ASK1 mutants: Experimental and molecular simulation study. Computational Biology and Chemistry 99, pages 107712.
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Sergiy A. Starosyla, Galyna P. Volynets, Sergiy S. Lukashov, Oksana B. Gorbatiuk, Andriy G. Golub, Volodymyr G. Bdzhola & Sergiy M. Yarmoluk. (2015) Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one. Bioorganic & Medicinal Chemistry 23:10, pages 2489-2497.
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Sergiy A. Starosyla, Galyna P. Volynets, Volodymyr G. Bdzhola, Andriy G. Golub, Mykola V. Protopopov & Sergiy M. Yarmoluk. (2014) ASK1 pharmacophore model derived from diverse classes of inhibitors. Bioorganic & Medicinal Chemistry Letters 24:18, pages 4418-4423.
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Michael P Bova & Gene G Kinney. (2013) Emerging drug targets in amyotrophic lateral sclerosis. Expert Opinion on Orphan Drugs 1:1, pages 5-20.
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Stefano Toldo, David G. Breckenridge, Eleonora Mezzaroma, Benjamin W. Van Tassell, John Shryock, Harsha Kannan, Dillon Phan, Grant Budas, Daniela Farkas, Edward Lesnefsky, Norbert Voelkel & Antonio Abbate. (2012) Inhibition of Apoptosis Signal–Regulating Kinase 1 Reduces Myocardial Ischemia–Reperfusion Injury in the Mouse. Journal of the American Heart Association 1:5.
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