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Leucine-rich repeat kinase 2 inhibitors: a patent review (2006 – 2011)

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Pages 1415-1426 | Published online: 06 Nov 2012

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Xiao Ding & Feng Ren. (2020) Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-present). Expert Opinion on Therapeutic Patents 30:4, pages 275-286.
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Raghava R Kethiri & Rajagopal Bakthavatchalam. (2014) Leucine-rich repeat kinase 2 inhibitors: a review of recent patents (2011 – 2013). Expert Opinion on Therapeutic Patents 24:7, pages 745-757.
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Robert K. Leśniak, R. Jeremy Nichols, Marcus Schonemann, Jing Zhao, Chandresh R. Gajera, William L. Fitch, Grace Lam, Khanh C. Nguyen, Mark Smith & Thomas J. Montine. (2022) Discovery of G2019S-Selective Leucine Rich Repeat Protein Kinase 2 inhibitors with in vivo efficacy. European Journal of Medicinal Chemistry 229, pages 114080.
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Evan H Howlett, Nicholas Jensen, Frances Belmonte, Faria Zafar, Xiaoping Hu, Jillian Kluss, Birgitt Schüle, Brett A Kaufman, J T Greenamyre & Laurie H Sanders. (2017) LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease. Human Molecular Genetics 26:22, pages 4340-4351.
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