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Benzofuran derivatives: a patent review

Pages 1133-1156 | Published online: 17 May 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Ghazaleh Zarrinzadeh, Mahmood Tajbakhsh, Rahman Hosseinzadeh, Mohammad A. Khalilzadeh & Masoumeh Hosseinzadeh. (2023) Biological Evaluation and Molecular Docking Study of Euparin and Its Maleic Anhydride and Semicarbazide Derivatives. Polycyclic Aromatic Compounds 43:1, pages 409-420.
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Ashraf A. Abbas & Kamal M. Dawood. (2022) Benzofuran as a promising scaffold for the synthesis of novel antimicrobial agents. Expert Opinion on Drug Discovery 17:12, pages 1357-1376.
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Mei-Yue Dong, Yan Zhang, Hai-Qiang Jiang, Wen-Jing Ren, Ling-Chuan Xu, Yong-Qing Zhang & Yu-Hong Liu. (2021) Benzofuran derivatives with nerve growth factor-potentiating activity from Phellinus ribis. Natural Product Research 35:23, pages 5145-5152.
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Vallabhaneni S. Murthy, Yasinalli Tamboli, Vagolu Siva Krishna, Dharmarajan Sriram, Siddique Akber Ansari, Abdullah A. Alarfaj, Abdurahman H. Hirad & Vijayaparthasarathi Vijayakumar. (2021) Design and characterisation of piperazine-benzofuran integrated dinitrobenzenesulfonamide as Mycobacterium tuberculosis H37Rv strain inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1751-1759.
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Kamal M. Dawood & Ashraf A. Abbas. (2020) Inhibitory activities of indolizine derivatives: a patent review. Expert Opinion on Therapeutic Patents 30:9, pages 695-714.
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Mostafa E. Salem, Ahmed F. Darweesh & Ahmed H. M. Elwahy. (2020) Synthesis of novel scaffolds based on thiazole or triazolothiadiazine linked to benzofuran or benzo[d]thiazole moieties as new hybrid molecules. Synthetic Communications 50:2, pages 256-270.
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Bhushan Nazirkar, Mustapha Mandewale & Ramesh Yamgar. (2019) Synthesis, characterization and antibacterial activity of Cu (II) and Zn (II) complexes of 5-aminobenzofuran-2-carboxylate Schiff base ligands. Journal of Taibah University for Science 13:1, pages 440-449.
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Kamal M Dawood. (2019) An update on benzofuran inhibitors: a patent review. Expert Opinion on Therapeutic Patents 29:11, pages 841-870.
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Shichun Jiang, Wei Wang, Chengli Mou, Juan Zou, Zhichao Jin, Gefei Hao & Yonggui Robin Chi. (2023) Facile access to benzofuran derivatives through radical reactions with heteroatom-centered super-electron-donors. Nature Communications 14:1.
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A.G. Pramod, Y.F. Nadaf & C.G. Renuka. (2019) Synthesis, photophysical, quantum chemical investigation, linear and non-linear optical properties of coumarin derivative: Optoelectronic and optical limiting application. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 223, pages 117288.
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Veerabhadrayya S. Negalurmath, Obelannavar Kotresh & Mahantesha Basanagouda. (2019) Synthesis and Preliminary Evaluation of Benzofuran-Oxadiazole Conjugates as Potential Antitubercular Agents. Asian Journal of Chemistry 31:4, pages 965-970.
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Sudhir M. Hiremath, Anil S. Patil, Chidanandayya S. Hiremath, Mahantesha Basangouda, Seema S. Khemalapure, Ninganagouda R. Patil, Shivaraj B. Radder, Sanja J. Armaković & Stevan Armaković. (2019) Structural, spectroscopic characterization of 2-(5-methyl-1-benzofuran-3-yl) acetic acid in monomer, dimer and identification of specific reactive, drug likeness properties: Experimental and computational study. Journal of Molecular Structure 1178, pages 1-17.
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Veerabhadrayya S. Negalurmath, Sathish Kumar Boda, Obelannavar Kotresh, P.V. Anantha Lakshmi & Mahantesha Basanagouda. (2019) Benzofuran-oxadiazole hybrids: Design, synthesis, antitubercular activity and molecular docking studies. Chemical Data Collections 19, pages 100178.
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Sudhir M. Hiremath, A. Suvitha, Ninganagouda R. Patil, Chidanandayya S. Hiremath, Seema S. Khemalapure, Subrat K. Pattanayak, Veerabhadrayya S. Negalurmath, Kotresh Obelannavar, Sanja J. Armaković & Stevan Armaković. (2018) Synthesis of 5-(5-methyl-benzofuran-3-ylmethyl)-3H- [1, 3, 4] oxadiazole-2-thione and investigation of its spectroscopic, reactivity, optoelectronic and drug likeness properties by combined computational and experimental approach. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 205, pages 95-110.
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Arvind Kumar, Michael Saleeb, Dominik Werz & Mikael Elofsson. (2018) Cyclopropylmethyl Protection of Phenols: Total Synthesis of the Resveratrol Dimers Anigopreissin A and Resveratrol–Piceatannol Hybrid. ChemistryOpen 7:12, pages 953-956.
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Sudhir M. Hiremath, A. Suvitha, Ninganagouda R. Patil, Chidanandayya S. Hiremath, Seema S. Khemalapure, Subrat K. Pattanayak, Veerabhadrayya S. Negalurmath & Kotresh Obelannavar. (2018) Molecular structure, vibrational spectra, NMR, UV, NBO, NLO, HOMO-LUMO and molecular docking of 2-(4, 6-dimethyl-1-benzofuran-3-yl) acetic acid (2DBAA): Experimental and theoretical approach. Journal of Molecular Structure 1171, pages 362-374.
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Deepti Goyal, Amandeep Kaur & Bhupesh Goyal. (2018) Benzofuran and Indole: Promising Scaffolds for Drug Development in Alzheimer's Disease. ChemMedChem 13:13, pages 1275-1299.
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Li‐Cheng Yang, Zher Yin Tan, Zi‐Qiang Rong, Ruoyang Liu, Ya‐Nong Wang & Yu Zhao. (2018) Palladium‐Titanium Relay Catalysis Enables Switch from Alkoxide‐π‐Allyl to Dienolate Reactivity for Spiro‐Heterocycle Synthesis. Angewandte Chemie 130:26, pages 7986-7990.
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Antonio Puglisi, Chiara Giustini, Angela Ricucci, Elisa Perotti, Luca Massaro, Diego Morra, Flavia Ciucci, Alessio Zucchet, Achille Antenucci, Mauro Moliterno, Simone Placidi, Fabio Sciubba, Luciano Galantini, Riccardo Salvio & Marco Bella. (2018) Synthesis of Benzofuranones via Malonates Desymmetrization: Yield Increase by the Portion‐wise Addition of Quinones. Chemistry – A European Journal 24:27, pages 6941-6945.
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Michael Saleeb, Sergio Mojica, Anna U. Eriksson, C. David Andersson, Åsa Gylfe & Mikael Elofsson. (2018) Natural product inspired library synthesis - Identification of 2,3-diarylbenzofuran and 2,3-dihydrobenzofuran based inhibitors of Chlamydia trachomatis. European Journal of Medicinal Chemistry 143, pages 1077-1089.
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Sobhi M. Gomha & Kamal M. Dawood. (2017) Synthetic Utility of Pyridinium Bromide: Synthesis and Antimicrobial Activity of Novel 2,4,6‐Trisubstituted Pyridines Having Pyrazole Moiety. Journal of Heterocyclic Chemistry 54:3, pages 1943-1948.
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Phuong-Thuy Phan, Thu-Trang Nguyen, Hong-Nhung Nguyen, Bao-Khanh Le, Thao Vu, Dong Tran & Tuan-Anh Pham. (2017) Synthesis and Bioactivity Evaluation of Novel 2-Salicyloylbenzofurans as Antibacterial Agents. Molecules 22:5, pages 687.
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Li‐Cheng Yang, Zi‐Qiang Rong, Ya‐Nong Wang, Zher Yin Tan, Min Wang & Yu Zhao. (2017) Construction of Nine‐Membered Heterocycles through Palladium‐Catalyzed Formal [5+4] Cycloaddition. Angewandte Chemie International Edition 56:11, pages 2927-2931.
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Li-Cheng Yang, Zi-Qiang Rong, Ya-Nong Wang, Zher Yin Tan, Min Wang & Yu Zhao. (2017) Construction of Nine-Membered Heterocycles through Palladium-Catalyzed Formal [5+4] Cycloaddition. Angewandte Chemie 129:11, pages 2973-2977.
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Sachin S. IchakeAshok KonalaVeerababurao KavalaChun-Wei KuoChing-Fa Yao. (2016) Palladium-Catalyzed Tandem C–H Functionalization/Cyclization Strategy for the Synthesis of 5-Hydroxybenzofuran Derivatives. Organic Letters 19:1, pages 54-57.
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