Citations (29)
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Simone Schierle & Daniel Merk. (2019) Therapeutic modulation of retinoid X receptors – SAR and therapeutic potential of RXR ligands and recent patents. Expert Opinion on Therapeutic Patents 29:8, pages 605-621.
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Articles from other publishers (26)
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Maho Takioku, Yuta Takamura, Michiko Fujihara, Masaki Watanabe, Shoya Yamada, Mayu Kawasaki, Sohei Ito, Shogo Nakano & Hiroki Kakuta. (2021) Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay. ACS Medicinal Chemistry Letters 12:6, pages 1024-1029.
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Julius Brtko. (2021) Thyroid hormone and thyroid hormone nuclear receptors: History and present state of art. Endocrine Regulations 55:2, pages 103-119.
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Pei Yu, Kai Yang & Min Jiang. (2021) RXRα Blocks Nerve Regeneration after Spinal Cord Injury by Targeting p66shc. Oxidative Medicine and Cellular Longevity 2021, pages 1-10.
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Julius Brtko & Zdenek Dvorak. (2020) Natural and synthetic retinoid X receptor ligands and their role in selected nuclear receptor action. Biochimie 179, pages 157-168.
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Junyan Tao, Chenglian Bai, Yuanhong Chen, Huanhuan Zhou, Yahui Liu, Qingyu Shi, Wenhao Pan, Haojia Dong, Luyi Li, Hui Xu, Robyn Tanguay, Changjiang Huang & Qiaoxiang Dong. (2020) Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish. Science of The Total Environment 721, pages 137686.
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Nitin Chitranshi, Yogita Dheer, Sanjay Kumar, Stuart L. Graham & Vivek Gupta. (2019) Molecular docking, dynamics, and pharmacology studies on bexarotene as an agonist of ligand‐activated transcription factors, retinoid X receptors. Journal of Cellular Biochemistry 120:7, pages 11745-11760.
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Atef Nehdi, Rizwan Ali, Alshaimaa Alhallaj, Hajar Alzahrani, Nosaibah Samman, Abdullah Mashhour, Omar Baz, Tlili Barhoumi, Bandar Alghanem, Abdullatif Khan, Lolwah Alriyees & Mohamed Boudjelal. (2019) Nuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells. Molecules 24:11, pages 2028.
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Pascal Heitel, Leonie Gellrich, Lena Kalinowsky, Jan Heering, Astrid Kaiser, Julia Ohrndorf, Ewgenij Proschak & Daniel Merk. (2019) Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype. ACS Medicinal Chemistry Letters 10:2, pages 203-208.
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Judit Osz, Alastair G. McEwen, Justine Wolf, Pierre Poussin-Courmontagne, Carole Peluso-Iltis, Yassmine Chebaro, Bruno Kieffer & Natacha Rochel. (2019) Modulation of RXR-DNA complex assembly by DNA context. Molecular and Cellular Endocrinology 481, pages 44-52.
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Francesca Grisoni, Daniel Merk, Ryan Byrne & Gisbert Schneider. (2018) Scaffold-Hopping from Synthetic Drugs by Holistic Molecular Representation. Scientific Reports 8:1.
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Weili Zheng, Yi Lu, Siyu Tian, Fengge Ma, Yijuan Wei, Shuangshuang Xu & Yong Li. (2018) Structural insights into the heterodimeric complex of the nuclear receptors FXR and RXR. Journal of Biological Chemistry 293:32, pages 12535-12541.
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Daniel Merk, Francesca Grisoni, Lukas Friedrich, Elena Gelzinyte & Gisbert Schneider. (2018) Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics. Journal of Medicinal Chemistry 61:12, pages 5442-5447.
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Daniel Merk, Francesca Grisoni, Lukas Friedrich, Elena Gelzinyte & Gisbert Schneider. (2018)
Scaffold hopping from synthetic RXR modulators by virtual screening and
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D. Flodrova, L. Toporova, M. Lastovickova, D. Macejova, L. Hunakova, J. Brtko & J. Bobalova. (2017) Consequences of the natural retinoid/retinoid X receptor ligands action in human breast cancer MDA-MB-231 cell line: Focus on functional proteomics. Toxicology Letters 281, pages 26-34.
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María P. Menéndez-Gutiérrez & Mercedes Ricote. (2017) The multi-faceted role of retinoid X receptor in bone remodeling. Cellular and Molecular Life Sciences 74:12, pages 2135-2149.
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Lucia Toporova, Dana Macejova & Julius Brtko. (2016) Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands. Toxicology Letters 254, pages 32-36.
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Cindy Benod, Rosa Villagomez & Paul Webb. (2016) TLX: An elusive receptor. The Journal of Steroid Biochemistry and Molecular Biology 157, pages 41-47.
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Daniel Merk. (2015) Chances and challenges of retinoid X receptor gamma targeting for regenerative multiple sclerosis treatment. Future Medicinal Chemistry 7:18, pages 2411-2413.
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Yanyan Sun, Jun Fan, Zhiyuan Zhu, Xiaodan Guo, Tingting Zhou, Wenhu Duan & Xu Shen. (2015) Small molecule TBTC as a new selective retinoid X receptor ? agonist improves behavioral deficit in Alzheimer's disease model mice. European Journal of Pharmacology 762, pages 202-213.
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J. Brtko & Z. Dvorak. (2015) Triorganotin compounds - ligands for “rexinoid” inducible transcription factors: Biological effects. Toxicology Letters 234:1, pages 50-58.
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Kohei Kawata, Ken-ichi Morishita, Mariko Nakayama, Shoya Yamada, Toshiki Kobayashi, Yuki Furusawa, Sakae Arimoto-Kobayashi, Toshitaka Oohashi, Makoto Makishima, Hirotaka Naitou, Erika Ishitsubo, Hiroaki Tokiwa, Akihiro Tai & Hiroki Kakuta. (2014) RXR Partial Agonist Produced by Side Chain Repositioning of Alkoxy RXR Full Agonist Retains Antitype 2 Diabetes Activity without the Adverse Effects. Journal of Medicinal Chemistry 58:2, pages 912-926.
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