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Patent Evaluations

Anti-IL-36R antibodies, potentially useful for the treatment of psoriasis: a patent evaluation of WO2013074569

, BA & , MD PhD

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Mona El-Kalioby, Mohamed H. M. EL-Komy, Eman R. Said, Marwa Ahmed Amer, Dina G. Saadi, Faisal Nouredin Mohammed, Laila A. Rashed, Eman D. El Desouky & Aya M. AlOrbani. (2022) Downregulation of interleukin 36γ and its cleaver cathepsin G following treatment with narrow-band ultraviolet B phototherapy in psoriasis vulgaris. Journal of Dermatological Treatment 33:4, pages 2358-2363.
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Ulrike Hüffmeier, Janine KlimaMScMSc & Mohammad Deen Hayatu. (2023) Genetic underpinnings of the psoriatic spectrum. Medizinische Genetik 35:1, pages 46-54.
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Markus F. Neurath. (2020) IL-36 in chronic inflammation and cancer. Cytokine & Growth Factor Reviews 55, pages 70-79.
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Anne Müller, Antje Dickmanns, Claudia Resch, Knut Schäkel, Stephan Hailfinger, Matthias Dobbelstein, Klaus Schulze-Osthoff & Daniela Kramer. (2020) The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. Journal of Clinical Investigation 130:11, pages 5765-5781.
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Marie-Astrid Boutet, Alessandra Nerviani, Gloria Lliso-Ribera, Davide Lucchesi, Edoardo Prediletto, Giulia Maria Ghirardi, Katriona Goldmann, Myles Lewis & Costantino Pitzalis. (2020) Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis. Rheumatology 59:4, pages 828-838.
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Lula María Nieto Benito, Ángel Manuel Rosell Díaz, Ana Mateos Mayo, Carmen Rodríguez Sáinz, Ricardo María Suárez Fernández & Ofelia Baniandrés Rodríguez. (2019) Pustulosis palmoplantar: características epidemiológicas, clínicas y genéticas de una serie de 41 casos. Piel 34:5, pages 266-271.
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Satveer K. Mahil, Jonathan N. Barker & Francesca Capon. 2019. Textbook of Autoinflammation. Textbook of Autoinflammation 471 484 .
S. Hessam, M. Sand, T. Gambichler, M. Skrygan, I. Rüddel & F.G. Bechara. (2018) Interleukin-36 in hidradenitis suppurativa: evidence for a distinctive proinflammatory role and a key factor in the development of an inflammatory loop. British Journal of Dermatology 178:3, pages 761-767.
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William R. Swindell, Maria A. Beamer, Mrinal K. Sarkar, Shannon Loftus, Joseph Fullmer, Xianying Xing, Nicole L. Ward, Lam C. Tsoi, Michelle J. Kahlenberg, Yun Liang & Johann E. Gudjonsson. (2018) RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature. Frontiers in Immunology 9.
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Andrew Johnston. 2018. Neutrophilic Dermatoses. Neutrophilic Dermatoses 129 143 .
R. Thomi, M. Kakeda, N. Yawalkar, C. Schlapbach & R.E. Hunger. (2017) Increased expression of the interleukin-36 cytokines in lesions of hidradenitis suppurativa. Journal of the European Academy of Dermatology and Venereology 31:12, pages 2091-2096.
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Andrew Johnston, Xianying Xing, Liza Wolterink, Drew H. Barnes, ZhiQiang Yin, Laura Reingold, J. Michelle Kahlenberg, Paul W. Harms & Johann E. Gudjonsson. (2017) IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis. Journal of Allergy and Clinical Immunology 140:1, pages 109-120.
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Ting Xiao, Hong-Duo Chen, Jixin Gao, Gang Wang, Jeffrey D. Cizenski, Darlene Gou, Alan Menter, Li-Ping Zhao, Ru Yan, Yan Wu, Jinping Yuan, Hong-Hui Xu, Xing-Hua Gao & Hong-Duo Chen. 2017. Practical Immunodermatology. Practical Immunodermatology 221 258 .
Satveer K. Mahil, Sophie Twelves, Katalin Farkas, Niovi Setta-Kaffetzi, A. David Burden, Joanna E. Gach, Alan D. Irvine, László Képíró, Maja Mockenhaupt, Hazel H. Oon, Jason Pinner, Annamari Ranki, Marieke M.B. Seyger, Pere Soler-Palacin, Eoin R. Storan, Eugene S. Tan, Laurence Valeyrie-Allanore, Helen S. Young, Richard C. Trembath, Siew-Eng Choon, Marta Szell, Zsuzsanna Bata-Csorgo, Catherine H. Smith, Paola Di Meglio, Jonathan N. Barker & Francesca Capon. (2016) AP1S3 Mutations Cause Skin Autoinflammation by Disrupting Keratinocyte Autophagy and Up-Regulating IL-36 Production. Journal of Investigative Dermatology 136:11, pages 2251-2259.
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Angelo Massimiliano D'Erme, Dagmar Wilsmann-Theis, Julia Wagenpfeil, Michael Hölzel, Sandra Ferring-Schmitt, Sonja Sternberg, Miriam Wittmann, Bettina Peters, Andreas Bosio, Thomas Bieber & Joerg Wenzel. (2015) IL-36γ (IL-1F9) Is a Biomarker for Psoriasis Skin Lesions. Journal of Investigative Dermatology 135:4, pages 1025-1032.
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Safia Hussain, Dorottya M. Berki, Siew-Eng Choon, A. David Burden, Michael H. Allen, Juan I. Arostegui, Antonio Chaves, Michael Duckworth, Alan D. Irvine, Maja Mockenhaupt, Alexander A. Navarini, Marieke M.B. Seyger, Pere Soler-Palacin, Christa Prins, Laurence Valeyrie-Allanore, M. Asuncion Vicente, Richard C. Trembath, Catherine H. Smith, Jonathan N. Barker & Francesca Capon. (2015) IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis. Journal of Allergy and Clinical Immunology 135:4, pages 1067-1070.e9.
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D V Zaslavskiy, I N Chuprov, A A Sydikov, K U Ibragimov, P Wolkenstein, S V Skrek & R A Nasyrov. (2015) The role of IL-36γ/IL-1F9 in developing erythroderma in patients with psoriasis. Kazan medical journal 96:1, pages 80-84.
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