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p38 MAPK inhibitors: a patent review (2012 – 2013)

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Edward Richardson, David García-Bernal, Eleonora Calabretta, Rubén Jara, Marta Palomo, Rebecca M. Baron, Gregory Yanik, Jawed Fareed, Israel Vlodavsky, Massimo Iacobelli, Maribel Díaz-Ricart, Paul G. Richardson, Carmelo Carlo-Stella & Jose M. Moraleda. (2021) Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes. Expert Opinion on Therapeutic Targets 25:6, pages 423-433.
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Vanessa Haller, Philipp Nahidino, Michael Forster & Stefan A. Laufer. (2020) An updated patent review of p38 MAP kinase inhibitors (2014-2019). Expert Opinion on Therapeutic Patents 30:6, pages 453-466.
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Sivagami Giridharan & Mythily Srinivasan. (2018) Mechanisms of NF-κB p65 and strategies for therapeutic manipulation. Journal of Inflammation Research 11, pages 407-419.
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Paul Glossop, Gavin Whitlock & Karl Gibson. (2015) Small-molecule anti-inflammatory drug compositions for the treatment of asthma: a patent review (2013 – 2014). Expert Opinion on Therapeutic Patents 25:7, pages 743-754.
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Melissa Chassé & Neil Vasdev. (2023) Synthesis and Preclinical Positron Emission Tomography Imaging of the p38 MAPK Inhibitor [ 11 C]Talmapimod: Effects of Drug Efflux and Sex Differences . ACS Chemical Neuroscience 14:11, pages 2193-2200.
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Deyun Meng, Baohua Zhang, Yanyan Wang, Tingting Zheng, Ran Hu, Bin Wang, Kinya OtsuYing Wang & Gonghua Huang. (2022) p38α Deficiency in T Cells Ameliorates Diet-Induced Obesity, Insulin Resistance, and Adipose Tissue Senescence. Diabetes 71:6, pages 1205-1217.
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Esther Carrasco, Patricia Gomez-Gutierrez, Pedro M. Campos, Miguel Vega, Angel Messeguer & Juan Jesus Perez. (2022) Structure-Activity Studies of Novel Di-substituted [1,2,5]oxadiazolo [3,4-b]pyrazine Analogs Targeting the A-loop Regulatory Site of p38 MAP Kinase. Current Medicinal Chemistry 29:9, pages 1640-1653.
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Piotr Raubo, Richard Evans & Paul Willis. (2020) The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 30:18, pages 127412.
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Wanli You, Zhiye Tang & Chia-en A. Chang. (2019) Potential Mean Force from Umbrella Sampling Simulations: What Can We Learn and What Is Missed?. Journal of Chemical Theory and Computation 15:4, pages 2433-2443.
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Wanli You & Chia-en A. Chang. (2018) Role of Molecular Interactions and Protein Rearrangement in the Dissociation Kinetics of p38α MAP Kinase Type-I/II/III Inhibitors. Journal of Chemical Information and Modeling 58:5, pages 968-981.
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Shin-Hyung Park, Myeong-A Seong & Ho-Young Lee. (2016) p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells. Oncotarget 7:7, pages 8184-8199.
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Consolato Sergi. (2015) Hepatocellular Carcinoma, Fibrolamellar Variant: Diagnostic Pathologic Criteria and Molecular Pathology Update. A Primer. Diagnostics 6:1, pages 3.
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