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Coumarin derivatives: an updated patent review (2012 – 2014)

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Qiaoliang Li, Zhuoying He, Ruitian Luo, Tao Nie, Quejian Zhang, Ying Xu, Huimin Guan & Suwen Qi. (2019) Liquid chromatography combined with patter recognition to detect the metabolic profiling of corn kernels. Food and Agricultural Immunology 30:1, pages 713-726.
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Anastasia Detsi, Christos Kontogiorgis & Dimitra Hadjipavlou-Litina. (2017) Coumarin derivatives: an updated patent review (2015-2016). Expert Opinion on Therapeutic Patents 27:11, pages 1201-1226.
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Cheng Xiu, Zhou Hua, Bao sheng Xiao, Wen Jian Tang, Hai Pin Zhou & Xin Hua Liu. (2017) Novel benzopyran derivatives and their therapeutic applications: a patent review (2009–2016). Expert Opinion on Therapeutic Patents 27:9, pages 1031-1045.
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Gervais Bérubé. (2016) An overview of molecular hybrids in drug discovery. Expert Opinion on Drug Discovery 11:3, pages 281-305.
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Gergely Knorr, Konrad Hotzel, Avinash Chettri, Artem Skabeev, Maria Wächtler, Benjamin Dietzek-Ivanšić & Kalina Peneva. (2023) Unlocking the potential of ketocoumarins: efficient photosensitizers for sustainable light driven hydrogen evolution. Journal of Materials Chemistry A 11:43, pages 23260-23269.
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Tai-Jie Zhang, Zhao Ma, Hong-Ju Ma, Xing-Shan Tian, Wen-Lei Guo & Chun Zhang. (2023) Metabolic pathways modulated by coumarin to inhibit seed germination and early seedling growth in Eleusine indica. Plant Physiology and Biochemistry 203, pages 108035.
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Karla Almaraz & Manuel Amézquita‐Valencia. (2023) Pd‐Catalyzed Intramolecular Hydroaminocarbonylation of 3‐Allyl‐4‐arylaminocoumarins: Synthesis of Six‐ and Seven‐membered Ring Lactams Fused to the Coumarin Scaffold. ChemCatChem 15:16.
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Ezequiel F. Bruna-Haupt, Marcelle D. Perretti, Hugo A. Garro, Romen Carrillo, Félix Machín, Isabel Lorenzo-Castrillejo, Lucas Gutiérrez, Esteban G. Vega-Hissi, Macarena Mamberto, Mauricio Menacho-Marquez, Claudio O. Fernández, Celina García & Carlos R. Pungitore. (2023) Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents. ACS Omega 8:29, pages 26479-26496.
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Reihane Ghomashi, Shakila Ghomashi, Hamidreza Aghaei & Ahmad Reza Massah. (2023) Recent Advances in Biological Active Sulfonamide based Hybrid Compounds Part A: Two-Component Sulfonamide Hybrids. Current Medicinal Chemistry 30:4, pages 407-480.
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Krishna N. Mishra & Harish C. Upadhyay. (2022) Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents. Frontiers in Drug Discovery 2.
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Nutchareeporn Nillert, Chantana Boonyarat, Jariya Umka Welbat, Komsun Bunreungthong, Ploenthip Puthongking & Wanassanun Pannangrong. (2022) Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats. BMC Complementary Medicine and Therapies 22:1.
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Rebecca J. Ellaby, Lisa J. White, Jessica E. Boles, Sena Ozturk & Jennifer R. Hiscock. (2022) Supramolecular self-associating amphiphiles as aqueous pollutant scavengers. Organic & Biomolecular Chemistry 20:38, pages 7587-7592.
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Dario Matulja, Filip Vranješević, Maria Kolympadi Markovic, Sandra Kraljević Pavelić & Dean Marković. (2022) Anticancer Activities of Marine-Derived Phenolic Compounds and Their Derivatives. Molecules 27:4, pages 1449.
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Prakairat Tunit, Phanit Thammarat, Siriporn Okonogi & Chuda Chittasupho. (2022) Hydrogel Containing Borassus flabellifer L. Male Flower Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity. Gels 8:2, pages 126.
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Gerald Zirintunda, Savino Biryomumaisho, Keneth Iceland Kasozi, Gaber El-Saber Batiha, John Kateregga, Patrick Vudriko, Sarah Nalule, Deogracious Olila, Mariam Kajoba, Kevin Matama, Mercy Rukundo Kwizera, Mohammed M. Ghoneim, Mahmoud Abdelhamid, Sameh S. Zaghlool, Sultan Alshehri, Mohamed A. Abdelgawad & James Acai-Okwee. (2022) Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution?. Frontiers in Pharmacology 12.
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Jorge Anaya-Gil, Patricia Ramos-Morales, Adriana Muñoz-Hernandez, Adriana Bermúdez & Harold Gomez-Estrada. (2022) In vivo evaluation of the toxic activity and genotoxicity of the Hymenaea courbaril L.’s resin in Drosophila melanogaster. Saudi Journal of Biological Sciences 29:1, pages 480-488.
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Serafeim Alexopoulos, Anastasia Gkouskou, George Stravodimos, Anastasia S. Tsagkarakou, Ioannis Tsialtas, Demetres Katounis, Anna-Maria G. Psarra, Demetres Leonidas, Goutam Brahmachari, Joseph M. Hayes & Vasiliki Skamnaki. (2022) The druggability of the ATP binding site of glycogen phosphorylase kinase probed by coumarin analogues. Current Research in Chemical Biology 2, pages 100022.
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Diana Becerra, Jaime Portilla & Juan-Carlos Castillo. (2021) 2-Oxo-2H-chromen-7-yl 4-chlorobenzoate. Molbank 2021:3, pages M1279.
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Ines Cazin, Elisabeth Rossegger, Gema Guedes de la Cruz, Thomas Griesser & Sandra Schlögl. (2020) Recent Advances in Functional Polymers Containing Coumarin Chromophores. Polymers 13:1, pages 56.
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Y. Erdogdu, U.C. Baskose, S. Saglam, M. Erdogdu, H. Ogutcu & S Özçelik. (2020) Structural, thermal, spectroscopic, electronic and biological activity properties of coumarin-153 dyes for DSSCs: A DFT benchmark study. Journal of Molecular Structure 1221, pages 128873.
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Santiago García, Itzel Mercado-Sánchez, Luis Bahena, Yolanda Alcaraz, Marco A. García-Revilla, Juvencio Robles, Nancy Santos-Martínez, David Ordaz-Rosado, Rocío García-Becerra & Miguel A. Vazquez. (2020) Design of Fluorescent Coumarin-Hydroxamic Acid Derivatives as Inhibitors of HDACs: Synthesis, Anti-Proliferative Evaluation and Docking Studies. Molecules 25:21, pages 5134.
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Santhosh S. Kumar, Kirti Hira, Sajeli Begum Ahil, Onkar P. Kulkarni, Hiroshi Araya & Yoshinori Fujimoto. (2020) New synthetic coumarinolignans as attenuators of pro-inflammatory cytokines in LPS-induced sepsis and carrageenan-induced paw oedema models. Inflammopharmacology 28:5, pages 1365-1373.
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V. A. Zolottsev, A. S. Latysheva, V. S. Pokrovsky, I. I. KhanR. L. M. AlmanzaA. Y. Misharin. (2020) STEROID CONJUGATES AS POTENTIAL ANTI-CANCER AGENTS. Russian Journal of Biotherapy 19:1, pages 22-52.
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Alev Önder. 2020. Bioactive Natural Products. Bioactive Natural Products 85 109 .
Md Yousof Ali, Su Hui Seong, Hyun Ah Jung & Jae Sue Choi. (2019) Angiotensin-I-Converting Enzyme Inhibitory Activity of Coumarins from Angelica decursiva. Molecules 24:21, pages 3937.
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S. Santhosh Kumar, Ahil Sajeli Begum, Kirti Hira, Sarfaraj Niazi, B.R. Prashantha Kumar, Hiroshi Araya & Yoshinori Fujimoto. (2019) Structure-based design and synthesis of new 4-methylcoumarin-based lignans as pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) inhibitors. Bioorganic Chemistry 89, pages 102991.
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Guanglu Liu, Chunjie Wang, Haifeng Wang, Lili Zhu, Hui Zhang, Yunsheng Wang, Chaoyu Pei & Lei Liu. (2019) Antiviral efficiency of a coumarin derivative on spring viremia of carp virus in vivo. Virus Research 268, pages 11-17.
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Kotthireddy Kavitha, Devulapally Srikrishna, Pramod Kumar Dubey & Pasula Aparna. (2019) A Green and Efficient Synthesis of Substituted 2-(4-(2-Oxo-2H-chromen-3- yl)thiazol-2-yl)-3-phenylacrylonitriles Under Environmentally Benign Conditions. Letters in Organic Chemistry 16:8, pages 637-642.
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Hamideh Mohamadi Tanuraghaj & Mahnaz Farahi. (2019) A novel sodium carbonate-catalyzed regioselective synthesis of pyrano[2,3-h]coumarins using a three-component reaction. Tetrahedron Letters 60:7, pages 557-559.
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Michał Jóźwiak, Marta Struga, Piotr Roszkowski, Agnieszka Filipek, Grażyna Nowicka & Wioletta Olejarz. (2019) Anticancer effects of alloxanthoxyletin and fatty acids esters – In vitro study on cancer HTB-140 and A549 cells. Biomedicine & Pharmacotherapy 110, pages 618-630.
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Simon Vlad Luca, Kazimierz Głowniak & Krystyna Skalicka‐Woźniak. 2007. Encyclopedia of Analytical Chemistry. Encyclopedia of Analytical Chemistry 1 45 .
Juliana Santa Ardisson, Rita de Cássia Ribeiro Gonçalves, Ricardo Pereira Rodrigues & Rodrigo Rezende Kitagawa. (2018) Antitumour, Immunomodulatory activity and in silico studies of naphthopyranones targeting iNOS, a relevant target for the treatment of Helicobacter pylori infection. Biomedicine & Pharmacotherapy 107, pages 1160-1165.
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M. G. Lobo, N. Hounsome & B. Hounsome. 2018. Handbook of Vegetables and Vegetable Processing. Handbook of Vegetables and Vegetable Processing 47 82 .
Aline Witaicenis, Ellen Cristina Souza de Oliveira, Alexandre Tanimoto, Sofia Fernanda Gonçalves Zorzella-Pezavento, Silvio Luis de Oliveira, Alexandrina Sartori & Luiz Claudio Di Stasi. (2018) 4-methylesculetin, a coumarin derivative, ameliorates dextran sulfate sodium-induced intestinal inflammation. Chemico-Biological Interactions 280, pages 59-63.
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Na Lv, Ming Sun, Chen Liu & Jiabin Li. (2017) Design and synthesis of 2-phenylpyrimidine coumarin derivatives as anticancer agents. Bioorganic & Medicinal Chemistry Letters 27:19, pages 4578-4581.
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Md Ali, Su Seong, Machireddy Reddy, Sung Seo, Jae Choi & Hyun Jung. (2017) Kinetics and Molecular Docking Studies of 6-Formyl Umbelliferone Isolated from Angelica decursiva as an Inhibitor of Cholinesterase and BACE1. Molecules 22:10, pages 1604.
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Anna Marchese, Carla Arciola, Ramona Barbieri, Ana Silva, Seyed Nabavi, Arold Tsetegho Sokeng, Morteza Izadi, Nematollah Jafari, Ipek Suntar, Maria Daglia & Seyed Nabavi. (2017) Update on Monoterpenes as Antimicrobial Agents: A Particular Focus on p-Cymene. Materials 10:8, pages 947.
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Anshu Dandia, Shahnawaz Khan, Pragya Soni, Aayushi Indora, Dinesh Kumar Mahawar, Prateek Pandya & Chetan Singh Chauhan. (2017) Diversity-oriented sustainable synthesis of antimicrobial spiropyrrolidine/thiapyrrolizidine oxindole derivatives: New ligands for a metallo-β-lactamase from Klebsiella pneumonia. Bioorganic & Medicinal Chemistry Letters 27:13, pages 2873-2880.
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Le Pan, Xiuzhuang Li, Hui Jin, Xiaoyan Yang & Bo Qin. (2017) Antifungal activity of umbelliferone derivatives: Synthesis and structure-activity relationships. Microbial Pathogenesis 104, pages 110-115.
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Guo-Ying Zuo, Chun-Juan Wang, Jun Han, Yu-Qing Li & Gen-Chun Wang. (2016) Synergism of coumarins from the Chinese drug Zanthoxylum nitidum with antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA). Phytomedicine 23:14, pages 1814-1820.
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Igor A. Schepetkin, Andrei I. Khlebnikov, Liliya N. Kirpotina & Mark T. Quinn. (2016) Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives. International Immunopharmacology 37, pages 43-58.
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Md Yousof Ali, Susoma Jannat, Hyun Ah Jung, Hyong Oh Jeong, Hae Young Chung & Jae Sue Choi. (2016) Coumarins from Angelica decursiva inhibit α-glucosidase activity and protein tyrosine phosphatase 1B. Chemico-Biological Interactions 252, pages 93-101.
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E. Niro, R. Marzaioli, S. De Crescenzo, B. D'Abrosca, S. Castaldi, A. Esposito, A. Fiorentino & F.A. Rutigliano. (2016) Effects of the allelochemical coumarin on plants and soil microbial community. Soil Biology and Biochemistry 95, pages 30-39.
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Ehtesham Jameel, Tarana Umar, Jitendra Kumar & Nasimul Hoda. (2016) Coumarin: A Privileged Scaffold for the Design and Development of Antineurodegenerative Agents. Chemical Biology & Drug Design 87:1, pages 21-38.
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E. Calcio Gaudino, S. Tagliapietra, K. Martina, G. Palmisano & G. Cravotto. (2016) Recent advances and perspectives in the synthesis of bioactive coumarins. RSC Advances 6:52, pages 46394-46405.
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Renuka Nagamallu, Bharath Srinivasan, Mylarappa B. Ningappa & Ajay Kumar Kariyappa. (2016) Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities. Bioorganic & Medicinal Chemistry Letters 26:2, pages 690-694.
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Serafeim Alexopoulos, Anastasia Gkouskou, George Stravodimos, Anastasia S. Tsagkarakou, Ioannis Tsialtas, Demetres Katounis, Anna-Maria G. Psarra, Demetres Leonidas, Goutam Brahmachari, Joseph Hayes & Vasiliki Skamnaki. (2022) The Druggability of the ATP Binding Site of Glycogen Phosphorylase Kinase Probed by Coumarin Analogues. SSRN Electronic Journal.
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