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Drug Evaluations

Exenatide once weekly for the treatment of type 2 diabetes

, MD, , MD, , MD, , PhD & , MD
Pages 359-367 | Published online: 09 May 2009

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Taylor B. Smallwood & Richard J. Clark. (2021) Advances in venom peptide drug discovery: where are we at and where are we heading?. Expert Opinion on Drug Discovery 16:10, pages 1163-1173.
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Volker Herzig, Ben Cristofori-Armstrong, Mathilde R. Israel, Samantha A. Nixon, Irina Vetter & Glenn F. King. (2020) Animal toxins — Nature’s evolutionary-refined toolkit for basic research and drug discovery. Biochemical Pharmacology 181, pages 114096.
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Cristian Guja & Andrada Mihai. (2017) Exenatide QW – New Perspectives 5 Years after its First Use. Romanian Journal of Diabetes Nutrition and Metabolic Diseases 24:4, pages 281-287.
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Chris de Graaf, Dan Donnelly, Denise Wootten, Jesper Lau, Patrick M. Sexton, Laurence J. Miller, Jung-Mo Ahn, Jiayu Liao, Madeleine M. Fletcher, Dehua Yang, Alastair J. H. Brown, Caihong Zhou, Jiejie Deng & Ming-Wei Wang. (2016) Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic Successes. Pharmacological Reviews 68:4, pages 954-1013.
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Laurence G. Trahair, Michael Horowitz, Trygve Hausken, Christine Feinle-Bisset, Christopher K. Rayner & Karen L. Jones. (2014) Effects of Exogenous Glucagon-Like Peptide-1 on the Blood Pressure, Heart Rate, Mesenteric Blood Flow, and Glycemic Responses to Intraduodenal Glucose in Healthy Older Subjects. The Journal of Clinical Endocrinology & Metabolism 99:12, pages E2628-E2634.
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Chang Yu Pan, Ping Han, Xiaoming Liu, Shengli Yan, Ping Feng, Zhiguang Zhou, Xiaofeng Lv, Hui Tian, Yang Jin Kui, Benli Su, Shuhua Shang & Elisabeth Niemoeller. (2014) Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double‐blind, placebo‐controlled, 24‐week trial (GetGoal‐M‐Asia). Diabetes/Metabolism Research and Reviews 30:8, pages 726-735.
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G. B. Bolli & D. R. Owens. (2014) Lixisenatide, a novel GLP-1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitus. Diabetes, Obesity and Metabolism 16:7, pages 588-601.
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Ulrich Werner. (2014) Effects of the GLP-1 receptor agonist lixisenatide on postprandial glucose and gastric emptying – preclinical evidence. Journal of Diabetes and its Complications 28:1, pages 110-114.
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Giuseppe Derosa & Pamela Maffioli. 2014. Integrative Weight Management. Integrative Weight Management 261 277 .
Michael Horowitz, Christopher K. Rayner & Karen L. Jones. (2013) Mechanisms and Clinical Efficacy of Lixisenatide for the Management of Type 2 Diabetes. Advances in Therapy 30:2, pages 81-101.
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Sayaka Fukuda-Tsuru, Jun Anabuki, Yuji Abe, Kumiko Yoshida & Shinichi Ishii. (2012) A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations. European Journal of Pharmacology 696:1-3, pages 194-202.
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Jonathan D Roth, Mary R Erickson, Steve Chen & David G Parkes. (2012) GLP-1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities. British Journal of Pharmacology 166:1, pages 121-136.
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Maria Tzefos, Kira Harris & Adriane Brackett. (2012) Clinical Efficacy and Safety of Once-Weekly Glucagon-Like Peptide-1 Agonists in Development for Treatment of Type 2 Diabetes Mellitus in Adults. Annals of Pharmacotherapy 46:1, pages 68-78.
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Tetsuhiro Tanaka, Masaomi Nangaku & Akira Nishiyama. (2011) The role of incretins in salt-sensitive hypertension. Current Opinion in Nephrology & Hypertension 20:5, pages 476-481.
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Riccardo Perfetti. (2011) Combining Basal Insulin Analogs with Glucagon-Like Peptide-1 Mimetics. Diabetes Technology & Therapeutics 13:9, pages 873-881.
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Nicole R Pinelli & Kathryn M Hurren. (2011) Efficacy and Safety of Long-Acting Glucagon-Like Peptide-1 Receptor Agonists Compared with Exenatide Twice Daily and Sitagliptin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. Annals of Pharmacotherapy 45:7-8, pages 850-860.
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S. Madsbad, U. Kielgast, M. Asmar, C. F. Deacon, S. S. Torekov & J. J. Holst. (2011) An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future. Diabetes, Obesity and Metabolism 13:5, pages 394-407.
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Remy Burcelin, Cendrine Cabou, Christophe Magnan & Pierre Gourdy. 2011. Metabolic Syndrome. Metabolic Syndrome 279 325 .
Irina Vetter, Jasmine L. Davis, Lachlan D. Rash, Raveendra Anangi, Mehdi Mobli, Paul F. Alewood, Richard J. Lewis & Glenn F. King. (2010) Venomics: a new paradigm for natural products-based drug discovery. Amino Acids 40:1, pages 15-28.
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Que Liu, Lisa Adams, Anatoly Broyde, Rayne Fernandez, Alain D Baron & David G Parkes. (2010) The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats. Cardiovascular Diabetology 9:1.
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Taichi Ueda, Takaomi Ito, Kazuyoshi Tomita, Hiroko Togame, Masataka Fumoto, Kenji Asakura, Takeo Oshima, Shin-Ichiro Nishimura & Kohji Hanasaki. (2010) Identification of glycosylated exendin-4 analogue with prolonged blood glucose-lowering activity through glycosylation scanning substitution. Bioorganic & Medicinal Chemistry Letters 20:15, pages 4631-4634.
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Rudy Bilous & Richard Donnelly. 2010. Handbook of Diabetes. Handbook of Diabetes 79 86 .

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