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Pharmacological approaches to the treatment of obstructive sleep apnoea

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Pages 647-656 | Published online: 24 Apr 2009

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George A. Margaritopoulos, Maria A. Kokosi & Athol U. Wells. (2019) Diagnosing complications and co-morbidities of fibrotic interstitial lung disease. Expert Review of Respiratory Medicine 13:7, pages 645-658.
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Ching-Kai Su, Chiang-Ting Chou, Ko-Long Lin, Wei-Zhe Liang, Jin-Shiung Cheng, Hong-Tai Chang, I-Shu Chen, Ti Lu, Chun-Chi Kuo, Chia-Cheng Yu, Pochuen Shieh, Daih-Huang Kuo, Fu-An Chen & Chung-Ren Jan. (2016) Effect of protriptyline on [Ca2+] and viability in MG63 human osteosarcoma cells. Toxicology Mechanisms and Methods 26:8, pages 580-587.
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Hong-Tai Chang, Chiang-Ting Chou, Chia-Cheng Yu, Jeng-Yu Tsai, Te-Kung Sun, Wei-Zhe Liang, Ko-Long Lin, Hui-Wen Tseng, Chun-Chi Kuo, Fu-An Chen, Daih-Huang Kuo, Chih-Chuan Pan, Chin-Man Ho, Pochuen Shieh & Chung-Ren Jan. (2015) The mechanism of protriptyline-induced Ca2+ movement and non-Ca2+-triggered cell death in PC3 human prostate cancer cells. Journal of Receptors and Signal Transduction 35:5, pages 429-434.
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Malcolm Kohler & John R Stradling. (2011) Pitfalls of clinical trials on pharmacological treatment for obstructive sleep apnoea: future directions. Expert Opinion on Investigational Drugs 20:8, pages 1033-1037.
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Articles from other publishers (28)

Jan Hedner & Ding Zou. (2022) Turning Over a New Leaf—Pharmacologic Therapy in Obstructive Sleep Apnea. Sleep Medicine Clinics 17:3, pages 453-469.
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Ivana Rosenzweig, Nadia Gosselin & Romola S. Bucks. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine 60 74 .
Magda R. AbdelFattah, Song W. Jung, Melvin A. Greenspan, Mariela Padilla & Reyes Enciso. (2019) Efficacy of Antidepressants in the Treatment of Obstructive Sleep Apnea Compared to Placebo. A Systematic Review with Meta-Analyses.. Sleep and Breathing 24:2, pages 443-453.
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Thomas Gaisl, Sarah R. Haile, Sira Thiel, Martin Osswald & Malcolm Kohler. (2019) Efficacy of pharmacotherapy for OSA in adults: A systematic review and network meta-analysis. Sleep Medicine Reviews 46, pages 74-86.
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Thomaz A. Fleury Curado, Huy Pho, Olga Dergacheva, Slava Berger, Rachel Lee, Carla Freire, Aya Asherov, Luis U. Sennes, David Mendelowitz, Alan R. Schwartz & Vsevolod Y. Polotsky. (2018) Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice. Frontiers in Neurology 9.
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Jan Hedner & Ding Zou. (2018) Drug Therapy in Obstructive Sleep Apnea. Sleep Medicine Clinics 13:2, pages 203-217.
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David W Carley, Bharati Prasad, Kathryn J Reid, Roneil Malkani, Hryar Attarian, Sabra M Abbott, Boris Vern, Hui Xie, Chengbo Yuan & Phyllis C Zee. (2018) Pharmacotherapy of Apnea by Cannabimimetic Enhancement, the PACE Clinical Trial: Effects of Dronabinol in Obstructive Sleep Apnea. Sleep 41:1.
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Richard L. Horner, Kevin P. Grace & Andrew Wellman. (2017) A resource of potential drug targets and strategic decision-making for obstructive sleep apnoea pharmacotherapy. Respirology 22:5, pages 861-873.
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Garret A. Horton, Jimmy J. Fraigne, Zoltan A. Torontali, Matthew B. Snow, Jennifer L. Lapierre, Hattie Liu, Gaspard Montandon, John H. Peever & Richard L. Horner. (2017) Activation of the Hypoglossal to Tongue Musculature Motor Pathway by Remote Control. Scientific Reports 7:1.
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George A. Margaritopoulos, Katerina M. Antoniou & Athol U. Wells. (2017) Comorbidities in interstitial lung diseases. European Respiratory Review 26:143, pages 160027.
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Thomaz Fleury Curado, Kenneth Fishbein, Huy Pho, Michael Brennick, Olga Dergacheva, Luiz U. Sennes, Luu V. Pham, Ellen E. Ladenheim, Richard Spencer, David Mendelowitz, Alan R. Schwartz & Vsevolod Y. Polotsky. (2017) Chemogenetic stimulation of the hypoglossal neurons improves upper airway patency. Scientific Reports 7:1.
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Ivana Rosenzweig, Terri E. Weaver & Mary J. Morrell. 2017. Principles and Practice of Sleep Medicine. Principles and Practice of Sleep Medicine 1154 1166.e5 .
Ivana Rosenzweig, Martin Glasser, Dora Polsek, Guy D Leschziner, Steve C R Williams & Mary J Morrell. (2015) Sleep apnoea and the brain: a complex relationship. The Lancet Respiratory Medicine 3:5, pages 404-414.
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. 2015. ERS Handbook Self-Assessment in Respiratory Medicine. ERS Handbook Self-Assessment in Respiratory Medicine 71 72 .
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Kate Sutherland & Peter A Cistulli. (2015) Recent advances in obstructive sleep apnea pathophysiology and treatment. Sleep and Biological Rhythms 13:1, pages 26-40.
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Ana P. Abdala, John M. Bissonnette & Adrian Newman-Tancredi. (2014) Pinpointing brainstem mechanisms responsible for autonomic dysfunction in Rett syndrome: therapeutic perspectives for 5-HT1A agonists. Frontiers in Physiology 5.
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David Wang, Danny J. Eckert & Ronald R. Grunstein. (2013) Drug effects on ventilatory control and upper airway physiology related to sleep apnea. Respiratory Physiology & Neurobiology 188:3, pages 257-266.
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Klaus J. Wirth, Klaus Steinmeyer & Hartmut Ruetten. (2013) Sensitization of Upper Airway Mechanoreceptors as a New Pharmacologic Principle to Treat Obstructive Sleep Apnea: Investigations with AVE0118 in Anesthetized Pigs. Sleep 36:5, pages 699-708.
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S.C. Veasey. 2013. Encyclopedia of Sleep. Encyclopedia of Sleep 532 536 .
Octavian C. Ioachimescu & Nancy A. Collop. (2012) Sleep-Disordered Breathing. Neurologic Clinics 30:4, pages 1095-1136.
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Charalampos Mermigkis, Demetrios Mermigkis, Georgios Varouchakis & Sophia Schiza. (2011) CPAP treatment in patients with idiopathic pulmonary fibrosis and obstructive sleep apnea—therapeutic difficulties and dilemmas. Sleep and Breathing 16:1, pages 1-3.
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Jan Hedner, Ludger Grote & Ding Zou. 2011. Sleep Apnea. Sleep Apnea 535 550 .
Allan I. PackJan Hedner, Ludger Grote,Ding Zou. 2011. Sleep Apnea: Pathogenesis, Diagnosis and Treatment. Sleep Apnea: Pathogenesis, Diagnosis and Treatment 535 550 .
Malcolm Kohler & John R. Stradling. (2010) Mechanisms of vascular damage in obstructive sleep apnea. Nature Reviews Cardiology 7:12, pages 677-685.
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John M. Dopp & Barbara J. Morgan. (2010) Pharmacologic approaches for the management of symptoms and cardiovascular consequences of obstructive sleep apnea in adults. Sleep and Breathing 14:4, pages 307-315.
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W. McDowell Anderson & Sherwin M. Mina. (2010) Adjunctive Therapy to CPAP: Sedative Hypnotics, Heated Humidification, and Supplemental Oxygen. Sleep Medicine Clinics 5:3, pages 369-381.
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Peter R. EASTWOOD, Atul MALHOTRA, Lyle J. PALMER, Eric J. KEZIRIAN, Richard L. HORNER, Mary S. IP, Robert THURNHEER, Nick A. ANTIC & David R. HILLMAN. (2010) Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions. Respirology 15:4, pages 587-595.
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