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Expert Opinion on Investigational Drugs Volume 11, 2002 - Issue 10
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Review

Therapeutic developments in the treatment of amyotrophic lateral sclerosis

Mandy Jackson Department of Preclinical Veterinary Sciences, The University of Edinburgh, Edinburgh, EH9 1QH, Scotland, UK
,
Jerònia Lladó Department of Neurology, Johns Hopkins University School of Medicine, Meyer 6-109, 600 North Wolfe Street, Baltimore MD21287, USA. [email protected]
&
Jeffrey D Rothstein Department of Neurology, Johns Hopkins University School of Medicine, Meyer 6-109, 600 North Wolfe Street, Baltimore MD21287, USA
Pages 1343-1364 | Published online: 24 Feb 2005

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REUVEN SANDYK. (2006) SEROTONERGIC MECHANISMS IN AMYOTROPHIC LATERAL SCLEROSIS. International Journal of Neuroscience 116:7, pages 775-826.
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Michael Graves, Milan Fiala, Lu Anne Dinglasan, Nancy Liu, James Sayre, Francesco Chiappelli, Cees van Kooten & Harry Vinters. (2004) Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 5:4, pages 213-219.
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Articles from other publishers (16)

Teresa Cunha-Oliveira, Liliana Montezinho, Catarina Mendes, Omidreza Firuzi, Luciano Saso, Paulo J. Oliveira & Filomena S. G. Silva. (2020) Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention. Oxidative Medicine and Cellular Longevity 2020, pages 1-29.
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Jing Xu, Michelle H. Lacoske & Emmanuel A. Theodorakis. (2014) Neurotrophic Natural Products: Chemistry and Biology. Angewandte Chemie International Edition 53:4, pages 956-987.
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Jing Xu, Michelle H. Lacoske & Emmanuel A. Theodorakis. (2013) Neurotrophe Naturstoffe – ihre Chemie und Biologie. Angewandte Chemie 126:4, pages 972-1004.
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James Hynes, Sashi Nadanaciva, Rachel Swiss, Conn Carey, Sinead Kirwan & Yvonne Will. (2013) A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays. Toxicology in Vitro 27:2, pages 560-569.
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Yu Deng, Zhao-Fa Xu, Wei Liu, Bin Xu, Hai-Bo Yang & Yan-Gang Wei. (2012) Riluzole-Triggered GSH Synthesis via Activation of Glutamate Transporters to Antagonize Methylmercury-Induced Oxidative Stress in Rat Cerebral Cortex. Oxidative Medicine and Cellular Longevity 2012, pages 1-12.
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Andrew C. Elden, Hyung-Jun Kim, Michael P. Hart, Alice S. Chen-Plotkin, Brian S. Johnson, Xiaodong Fang, Maria Armakola, Felix Geser, Robert Greene, Min Min Lu, Arun Padmanabhan, Dana Clay-Falcone, Leo McCluskey, Lauren Elman, Denise Juhr, Peter J. Gruber, Udo Rüb, Georg Auburger, John Q. Trojanowski, Virginia M.-Y. Lee, Vivianna M. Van Deerlin, Nancy M. Bonini & Aaron D. Gitler. (2010) Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature 466:7310, pages 1069-1075.
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Ana Saavedra, Graça Baltazar & Emília P. Duarte. (2008) Driving GDNF expression: The green and the red traffic lights. Progress in Neurobiology 86:3, pages 186-215.
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Hidefumi Ito, Reika Wate, Jianhua Zhang, Shizuo Ohnishi, Satoshi Kaneko, Hisashi Ito, Satoshi Nakano & Hirofumi Kusaka. (2008) Treatment with edaravone, initiated at symptom onset, slows motor decline and decreases SOD1 deposition in ALS mice. Experimental Neurology 213:2, pages 448-455.
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John Hardy & Katrina Gwinn‐Hardy. 2008. Dementias. Dementias 189 192 .
Anne-Sophie Caumont, Jean-Noel Octave & Emmanuel Hermans. (2006) Specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in C6 glioma cells. Journal of Neurochemistry 97:1, pages 128-139.
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Celine Vermeiren, Isabelle Hemptinne, Nicolas Vanhoutte, Sebastien Tilleux, Jean-Marie Maloteaux & Emmanuel Hermans. (2006) Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis. Journal of Neurochemistry 96:3, pages 719-731.
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C. Risterucci, R. Coccurello, M. Banasr, J.M. Stutzmann, M. Amalric & A. Nieoullon. (2006) The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions. Neuroscience 137:1, pages 211-220.
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John P. Crow, Noel Y. Calingasan, Junyu Chen, Julie Lynch Hill & M. Flint Beal. (2005) Manganese porphyrin given at symptom onset markedly extends survival of ALS mice. Annals of Neurology 58:2, pages 258-265.
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Peter C Waldmeier & William G Tatton. (2004) Interrupting apoptosis in neurodegenerative disease: potential for effective therapy?. Drug Discovery Today 9:5, pages 210-218.
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Mookda Pattarawarapan & Kevin Burgess. (2003) Molecular Basis of Neurotrophin−Receptor Interactions. Journal of Medicinal Chemistry 46:25, pages 5277-5291.
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Barry W Festoff, Zhiming Suo & Bruce A Citron. (2003) Prospects for the Pharmacotherapy of Amyotrophic Lateral Sclerosis. CNS Drugs 17:10, pages 699-717.
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