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Review

Novel agents and strategies to treat herpes simplex virus infections

Pages 165-183 | Published online: 02 Mar 2005

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Yan Shen, Yang Lu, Mingli Jv, Jinshan Hu, Qian Li & Jiasheng Tu. (2011) Enhancing effect of Labrasol on the intestinal absorption of ganciclovir in rats. Drug Development and Industrial Pharmacy 37:12, pages 1415-1421.
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Adolfo C Fernandez-Obregon, Dhrumil Shah, Amanda I Howell, Imane Tiyal Bentahar, Lester Carrodeguas, Arifa Siddiqui & Julia A Ejiogu. (2008) Challenges in anti-infective therapy for skin conditions: part 1. Expert Review of Dermatology 3:3, pages 367-394.
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Oliver K Bernhard, Russell J Diefenbach & Anthony L Cunningham. (2005) New insights into viral structure and virus–cell interactions through proteomics. Expert Review of Proteomics 2:4, pages 577-588.
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Steven M Firestine. (2004) Recent advances in herpes simplex virus antiviral therapies. Expert Opinion on Therapeutic Patents 14:8, pages 1139-1151.
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Leonardo M. Nassani, Juliana C.H. Fernandes, Gustavo V.O. Fernandes & Louis Z.G. Touyz. (2023) Herpes gladiatorum in sports: An appraisal for health care worker and team dentists. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 35:5, pages 468-472.
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Ziwei Hu, Chaowei Zhang, Jianfeng Zhong, Hao Hu, Chenyang Li, Yunshi Zhao, Lu Wang, Liang Ye, Cong Yan, Mingzhong Wang, Qinchang Zhu, Bo Wen, Longxia He, Muhammad Shahid Riaz Rajoka, Xun Song & Zhendan He. (2023) Chelerythrine inhibits HSV-1 infection by suppressing virus binding to the cells. Pharmacological Research - Modern Chinese Medicine 6, pages 100223.
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Divya Gopinath, Kim Hoe Koe, Mari Kannan Maharajan & Swagatika Panda. (2023) A Comprehensive Overview of Epidemiology, Pathogenesis and the Management of Herpes Labialis. Viruses 15:1, pages 225.
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Lisa Clarke, Tara Maroke, Vidya Srinivasan & Meenakshi Rudralingam. (2021) Oral ulceration and vesiculobullous conditions in the paediatric patient. Dental Update 48:9, pages 771-780.
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Olga I. Yarovaya & Nariman F. Salakhutdinov. (2021) Mono- and sesquiterpenes as a starting platform for the development of antiviral drugs. Russian Chemical Reviews 90:4, pages 488-510.
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Sixian You, Yuan Liu, Zane Arp, Youbo Zhao, Eric J. Chaney, Marina Marjanovic & Stephen A. Boppart. (2017) Intracellular imaging of docosanol in living cells by coherent anti-Stokes Raman scattering microscopy. Journal of Biomedical Optics 22:7, pages 070502.
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Yong Chen, Tiphaine Zahui, Ingo Alberti & Yogeshvar N. Kalia. (2016) Cutaneous biodistribution of ionizable, biolabile aciclovir prodrugs after short duration topical iontophoresis: Targeted intraepidermal drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 99, pages 94-102.
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Stella Nowicki & Randall M. Goldblum. 2015. Mucosal Immunology. Mucosal Immunology 2251 2268 .
Benjamin W. Neuman, Peter Chamberlain, Fern Bowden & Jeremiah Joseph. (2014) Atlas of coronavirus replicase structure. Virus Research 194, pages 49-66.
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José Herrerías-Moreno & Irene Fuertes de Vega. (2014) Infecciones de la mucosa oral. Piel 29:4, pages 222-233.
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Xiang Li, Yuanyuan Liu, Xueling Hou, Hongjun Peng, Li Zhang, Qingbo Jiang, Mei Shi, Yun Ji, Yuyue Wang & Weifeng Shi. (2013) Chlorogenic Acid Inhibits the Replication and Viability of Enterovirus 71 In Vitro. PLoS ONE 8:9, pages e76007.
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A-Ram Lee, Soojin Yoon, Dong-Eun Kim & Yong-Joo Jeong. (2013) DNA Binding Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus Helicase. Bulletin of the Korean Chemical Society 34:4, pages 1260-1262.
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Mei-Gong Zhong, Yang-Fei Xiang, Xian-Xiu Qiu, Zhong Liu, Kaio Kitazato & Yi-Fei Wang. (2013) Natural products as a source of anti-herpes simplex virus agents. RSC Adv. 3:2, pages 313-328.
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Kevin D. Raney, Alicia K. Byrd & Suja Aarattuthodiyil. 2013. DNA Helicases and DNA Motor Proteins. DNA Helicases and DNA Motor Proteins 17 46 .
Stefanie Uibel, Anne Szerwinski, Karin Vitzthum, Daniel Müller, David Quarcoo & David A. Groneberg. (2014) Herpes simplex InfektionenHerpes simplex infections. Zentralblatt für Arbeitsmedizin, Arbeitsschutz und Ergonomie 61:11, pages 378-391.
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Jharna N. Shah & Roy F. Chemaly. 2011. Pulmonary Involvement in Patients with Hematological Malignancies. Pulmonary Involvement in Patients with Hematological Malignancies 301 311 .
Scott Thompson, Troy Messick, David C. Schultz, Melvin Reichman & Paul M. Lieberman. (2010) Development of a High-Throughput Screen for Inhibitors of Epstein-Barr Virus EBNA1. SLAS Discovery 15:9, pages 1107-1115.
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Zhe Ren, Chuan-hai Zhang, Lian-jun Wang, Yun-xia Cui, Ren-bin Qi, Chong-ren Yang, Ying-jun Zhang, Xiao-yi Wei, Da-xiang Lu & Yi-fei Wang. (2010) In vitro anti-viral activity of the total alkaloids from Tripterygium hypoglaucum against herpes simplex virus type 1. Virologica Sinica 25:2, pages 107-114.
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Hugh J. Field & Richard J. Whitley. 2010. Topley & Wilson's Microbiology and Microbial Infections. Topley & Wilson's Microbiology and Microbial Infections.
Claudia Simões, Tatiana Carvalho de Castro, Lívia da Silva Cordeiro, Norma Albarello, Elisabeth Mansur & Maria Teresa Villela Romanos. (2009) Antiviral activity of Cleome rosea extracts from field-grown plants and tissue culture-derived materials against acyclovir-resistant Herpes simplex viruses type 1 (ACVr-HSV-1) and type 2 (ACVr-HSV-2). World Journal of Microbiology and Biotechnology 26:1, pages 93-99.
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Nathalie Hasler-Nguyen, Donald Shelton, Gilbert Ponard, Marlene Bader, Martina Schaffrik & Pascal Mallefet. (2009) Evaluation of the in vitro skin permeation of antiviral drugs from penciclovir 1% cream and acyclovir 5% cream used to treat herpes simplex virus infection. BMC Dermatology 9:1.
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Henri AgutDavid BoutolleauClaire DebackPascale BonnafousAgnès Gautheret-Dejean. (2009) Testing the susceptibility of human herpesviruses to antivirals. Future Microbiology 4:9, pages 1111-1123.
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Kristjan S. Gudmundsson, Brian A. Johns & Jason Weatherhead. (2009) Pyrazolopyrimidines and pyrazolotriazines with potent activity against herpesviruses. Bioorganic & Medicinal Chemistry Letters 19:19, pages 5689-5692.
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Jin-Yan Chen, Wan-Nan Chen, Kwok-Man Vincent Poon, Bo-Jian Zheng, Xu Lin, Yong-Xiang Wang & Yu-Mei Wen. (2009) Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems. Archives of Virology 154:3, pages 507-512.
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Chun-Ting Su, John T.-A. Hsu, Hsing-Pang Hsieh, Pi-Han Lin, Ting-Chi Chen, Chuan-Liang Kao, Chun-Nan Lee & Sui-Yuan Chang. (2008) Anti-HSV activity of digitoxin and its possible mechanisms. Antiviral Research 79:1, pages 62-70.
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Kristjan S. Gudmundsson, Brian A. Johns & Scott H. Allen. (2008) Pyrazolopyridines with potent activity against herpesviruses: Effects of C5 substituents on antiviral activity. Bioorganic & Medicinal Chemistry Letters 18:3, pages 1157-1161.
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Mahnaz Fatahzadeh & Robert A. Schwartz. (2007) Human herpes simplex virus infections: Epidemiology, pathogenesis, symptomatology, diagnosis, and management. Journal of the American Academy of Dermatology 57:5, pages 737-763.
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Karen K. Biron. 2009. Human Herpesviruses. Human Herpesviruses 1219 1250 .
João P.C. Tomé, Eduarda M.P. Silva, Ana M.V.M. Pereira, Cristina M.A. Alonso, Maria A.F. Faustino, Maria G.P.M.S. Neves, Augusto C. Tomé, José A.S. Cavaleiro, Sabina A.P. Tavares, Ricardo R. Duarte, Maria F. Caeiro & Maria L. Valdeira. (2007) Synthesis of neutral and cationic tripyridylporphyrin-d-galactose conjugates and the photoinactivation of HSV-1. Bioorganic & Medicinal Chemistry 15:14, pages 4705-4713.
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Kristjan S. Gudmundsson & Brian A. Johns. (2007) Imidazo[1,2-a]pyridines with potent activity against herpesviruses. Bioorganic & Medicinal Chemistry Letters 17:10, pages 2735-2739.
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Festus M. Tolo, Geoffrey M. Rukunga, Faith W. Muli, Eliud N.M. Njagi, Wilson Njue, Kazuko Kumon, Geoffrey M. Mungai, Charles N. Muthaura, Joseph M. Muli, Lucia K. Keter, Esau Oishi & Mawuli W. Kofi-Tsekpo. (2006) Anti-viral activity of the extracts of a Kenyan medicinal plant Carissa edulis against herpes simplex virus. Journal of Ethnopharmacology 104:1-2, pages 92-99.
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Denis P. Lynch. 2006. Mucosal Immunology and Virology. Mucosal Immunology and Virology 99 156 .
Kristjan S. Gudmundsson, Brian A. Johns, Zhicheng Wang, Elizabeth M. Turner, Scott H. Allen, George A. Freeman, F. Leslie BoydJr.Jr., Connie J. Sexton, Dean W. Selleseth, Kelly R. Moniri & Katrina L. Creech. (2005) Synthesis of novel substituted 2-phenylpyrazolopyridines with potent activity against herpesviruses. Bioorganic & Medicinal Chemistry 13:18, pages 5346-5361.
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Lars H. Jensen, Annemette V. Thougaard, Morten Grauslund, Birgitte Søkilde, Elisabeth V. Carstensen, Henrik K. Dvinge, Dominic A. Scudiero, Peter B. Jensen, Robert H. Shoemaker & Maxwell Sehested. (2005) Substituted Purine Analogues Define a Novel Structural Class of Catalytic Topoisomerase II Inhibitors. Cancer Research 65:16, pages 7470-7477.
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Francisco C. Pereira, Arnold G. Fogg, Paolo Ugo, Erwing. P. Bergamo, Nelson.R. Stradiotto & Maria Valnice B. Zanoni. (2005) Determination of Iodide and Idoxuridine at a Glutaraldehyde‐Cross‐Linked Poly‐ L ‐Lysine Modified Glassy Carbon Electrode . Electroanalysis 17:14, pages 1309-1316.
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João P.C. Tomé, Maria G.P.M.S. Neves, Augusto C. Tomé, José A.S. Cavaleiro, Ana F. Mendonça, Inês N. Pegado, Ricardo Duarte & Maria L. Valdeira. (2005) Synthesis of glycoporphyrin derivatives and their antiviral activity against herpes simplex virus types 1 and 2. Bioorganic & Medicinal Chemistry 13:12, pages 3878-3888.
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Stella Nowicki & Randall M. Goldblum. 2005. Mucosal Immunology. Mucosal Immunology 1747 1762 .
Arun Chakrabarty & Karl Beutner. (2004) Therapy of other viral infections: herpes to hepatitis. Dermatologic Therapy 17:6, pages 465-490.
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Gerald Kleymann & Hans-Otto Werling. (2004) A Generally Applicable, High-Throughput Screening–Compatible Assay to Identify, Evaluate, and Optimize Antimicrobial Agents for Drug Therapy. SLAS Discovery 9:7, pages 578-587.
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Gerald Kleymann. (2016) Helicase Primase: Targeting the Achilles Heel of Herpes Simplex Viruses. Antiviral Chemistry and Chemotherapy 15:3, pages 135-140.
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Julian A. Tanner, Rory M. Watt, Yu-Bo Chai, Lin-Yu Lu, Marie C. Lin, J.S.Malik Peiris, Leo L.M. Poon, Hsiang-Fu Kung & Jian-Dong Huang. (2003) The Severe Acute Respiratory Syndrome (SARS) Coronavirus NTPase/Helicase Belongs to a Distinct Class of 5′ to 3′ Viral Helicases. Journal of Biological Chemistry 278:41, pages 39578-39582.
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