Citations (44)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (3)
Ugutz Unzueta, María Virtudes Céspedes, Neus Ferrer-Miralles, Isolda Casanova, Juan Cedano, José Luis Corchero, Joan Domingo-Espín, Antonio Villaverde, Ramón Mangues & Esther Vázquez. (2012) Intracellular CXCR4+ cell targeting with T22-empowered protein-only nanoparticles. International Journal of Nanomedicine 7, pages 4533-4544.
Read now
Read now
Cara A Mosley, Lawrence J Wilson, John M Wiseman, Jason W Skudlarek & Dennis C Liotta. (2009) Recent patents regarding the discovery of small molecule CXCR4 antagonists. Expert Opinion on Therapeutic Patents 19:1, pages 23-38.
Read now
Read now
. (2003) Chemokine CCR5 antagonists incorporating a 4-aminopiperidine scaffold. Expert Opinion on Therapeutic Patents 13:9, pages 1469-1473.
Read now
Read now
Articles from other publishers (41)
Sikandar ShaikhSikandar Shaikh. 2022. Advances in Imaging. Advances in Imaging
257
271
.
Hossein Jadvar, Xiaoyuan Chen, Weibo Cai & Umar Mahmood. (2018) Radiotheranostics in Cancer Diagnosis and Management. Radiology 286:2, pages 388-400.
Crossref
Crossref
Diana Passaro, Christine Tran Quang & Jacques Ghysdael. (2016) Microenvironmental cues for T-cell acute lymphoblastic leukemia development. Immunological Reviews 271:1, pages 156-172.
Crossref
Crossref
William Sterlacci, Shereen Saker, Bettina Huber, Michael Fiegl & Alexandar Tzankov. (2016) Expression of the CXCR4 ligand SDF-1/CXCL12 is prognostically important for adenocarcinoma and large cell carcinoma of the lung. Virchows Archiv 468:4, pages 463-471.
Crossref
Crossref
Guillaume Pierre Charles George, Federica Pisaneschi, Quang-Dé Nguyen & Eric Ofori Aboagye. (2015) Positron Emission Tomographic Imaging of CXCR4 in Cancer: Challenges and Promises. Molecular Imaging 14:1, pages 7290.2014.00041.
Crossref
Crossref
Philipp Ermert, Kerstin Moehle & Daniel Obrecht. 2014. Macrocycles in Drug Discovery. Macrocycles in Drug Discovery
283
338
.
Sarah Decker, Johannes Finter, Aaron James Forde, Sandra Kissel, Juerg Schwaller, Thomas Sebastian Mack, Anabel Kuhn, Nathanael Gray, Marie Follo, Hassan Jumaa, Meike Burger, Katja Zirlik, Dietmar Pfeifer, Chandrasekhar V. Miduturu, Hermann Eibel, Hendrik Veelken & Christine Dierks. (2014) PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival (PIM2/3) and CXCR4-Mediated Microenvironmental Interactions (PIM1). Molecular Cancer Therapeutics 13:5, pages 1231-1245.
Crossref
Crossref
Yasuhiro Suzuki, Hiroyuki Gatanaga, Natsuo Tachikawa & Shinichi Oka. (2014) Slow Turnover of HIV-1 Receptors on Quiescent CD4+ T Cells Causes Prolonged Surface Retention of gp120 Immune Complexes In Vivo. PLoS ONE 9:2, pages e86479.
Crossref
Crossref
Duha Fahham, Ido D. Weiss, Michal Abraham, Katia Beider, Wald Hanna, Zippora Shlomai, Orly Eizenberg, Gideon Zamir, Uzi Izhar, Oz M. Shapira, Amnon Peled & Ori Wald. (2012) In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non–small cell lung cancer. The Journal of Thoracic and Cardiovascular Surgery 144:5, pages 1167-1175.e1.
Crossref
Crossref
Y Zhang, S Patel, H Abdelouahab, M Wittner, C Willekens, S Shen, A Betems, V Joulin, P Opolon, O Bawa, F Pasquier, M Ito, N Fujii, P Gonin, E Solary, W Vainchenker, P Coppo, S De Botton & F Louache. (2012) CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model. Cell Death & Disease 3:10, pages e396-e396.
Crossref
Crossref
Hirokazu Tamamura. (2012) Development of Anti-HIV Agents Based on Chemical Biologyケミカルバイオロジーを基盤とした抗HIV剤の創製. YAKUGAKU ZASSHI 132:1, pages 69-78.
Crossref
Crossref
Oliver Demmer, Ingrid Dijkgraaf, Udo Schumacher, Luciana Marinelli, Sandro Cosconati, Eleni Gourni, Hans-Jürgen Wester & Horst Kessler. (2011) Design, Synthesis, and Functionalization of Dimeric Peptides Targeting Chemokine Receptor CXCR4. Journal of Medicinal Chemistry 54:21, pages 7648-7662.
Crossref
Crossref
Mitsuhiro Yamada, Hiroshi Kubo, Seiichi Kobayashi, Kota Ishizawa, Mei He, Takaya Suzuki, Naoya Fujino, Hiroyuki Kunishima, Masamitsu Hatta, Katsushi Nishimaki, Tetsuji Aoyagi, Kouichi Tokuda, Miho Kitagawa, Hisakazu Yano, Hirokazu Tamamura, Nobutaka Fujii & Mitsuo Kaku. (2011) The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury. Cellular & Molecular Immunology 8:4, pages 305-314.
Crossref
Crossref
Aizhi Zhu, Weiqiang Zhan, Zhongxing Liang, Younghyoun Yoon, Hua Yang, Hans E. Grossniklaus, Jianguo Xu, Mauricio Rojas, Mark Lockwood, James P. Snyder, Dennis C. Liotta & Hyunsuk Shim. (2010) Dipyrimidine Amines: A Novel Class of Chemokine Receptor Type 4 Antagonists with High Specificity. Journal of Medicinal Chemistry 53:24, pages 8556-8568.
Crossref
Crossref
Patrick L. Wagner, Elizabeth Hyjek, Madeline F. Vazquez, Danish Meherally, Yi Fang Liu, Paul A. Chadwick, Tatiana Rengifo, Gabriel L. Sica, Jeffrey L. Port, Paul C. Lee, Subroto Paul, Nasser K. Altorki & Anjali Saqi. (2009) CXCL12 and CXCR4 in adenocarcinoma of the lung: Association with metastasis and survival. The Journal of Thoracic and Cardiovascular Surgery 137:3, pages 615-621.
Crossref
Crossref
Hyunsuk Shim. 2009. CNS Cancer. CNS Cancer
813
845
.
James F. Demarest, Sara S. Sparks, Kathleen Schell, Shiro Shibayama, Charlene B. McDanal, Lei Fang, Kimberly K. Adkison, Anne Shachoy-Clark & Stephen C. Piscitelli. (2008) In Vitro and Clinical Investigation of the Relationship Between CCR5 Receptor Occupancy and Anti-HIV Activity of Aplaviroc. The Journal of Clinical Pharmacology 48:10, pages 1179-1188.
Crossref
Crossref
Antonio MastrolorenzoAlfonso MarescaStefano RusconiClaudiu T Supuran. (2008) Update on the development of HIV entry inhibitors. Future HIV Therapy 2:5, pages 479-507.
Crossref
Crossref
Catherine S. Adamson & Eric O. Freed. (2008) Recent progress in antiretrovirals – lessons from resistance. Drug Discovery Today 13:9-10, pages 424-432.
Crossref
Crossref
Weiqiang Zhan, Zhongxing Liang, Aizhi Zhu, Serdar Kurtkaya, Hyunsuk Shim, James P. Snyder & Dennis C. Liotta. (2007) Discovery of Small Molecule CXCR4 Antagonists. Journal of Medicinal Chemistry 50:23, pages 5655-5664.
Crossref
Crossref
Wieslaw M. Kazmierski, Kristjan S. Gudmundsson & Stephen C. Piscitelli. 2007. Annual Reports in Medicinal Chemistry Volume 42. Annual Reports in Medicinal Chemistry Volume 42
301
320
.
Steven J. DeMarco, Heiko Henze, Alexander Lederer, Kerstin Moehle, Reshmi Mukherjee, Barbara Romagnoli, John A. Robinson, Federico Brianza, Frank O. Gombert, Sergio Lociuro, Christian Ludin, Jan Willem Vrijbloed, Jürg Zumbrunn, Jean-Pierre Obrecht, Daniel Obrecht, Vincent Brondani, François Hamy & Thomas Klimkait. (2006) Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles. Bioorganic & Medicinal Chemistry 14:24, pages 8396-8404.
Crossref
Crossref
Jon Vabeno, Gregory V. Nikiforovich & Garland R. Marshall. (2006) Insight into the Binding Mode for Cyclopentapeptide Antagonists of the CXCR4 Receptor. Chemical Biology <html_ent glyph="@amp;" ascii="&"/> Drug Design 67:5, pages 346-354.
Crossref
Crossref
Wieslaw M. Kazmierski, Terry P. Kenakin & Kristjan S. Gudmundsson. (2006) Peptide, Peptidomimetic and Small-molecule Drug Discovery Targeting HIV-1 Host-cell Attachment and Entry through gp120, gp41, CCR5 and CXCR4+. Chemical Biology <html_ent glyph="@amp;" ascii="&"/> Drug Design 67:1, pages 13-26.
Crossref
Crossref
Meike BurgerTanja HartmannMyriam KromeJustyna RawlukHirokazu TamamuraNobutaka FujiiThomas J. KippsJan A. Burger. (2005) Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells. Blood 106:5, pages 1824-1830.
Crossref
Crossref
José López-Aldeguer, Koldo Aguirrebengoa, José Ramón Arribas, José A. Esté & José María Kindelán. (2005) New targets and new drugs in the treatment of HIV. Enfermedades Infecciosas y Microbiología Clínica 23, pages 33-40.
Crossref
Crossref
José López-Aldeguer, Koldo Aguirrebengoa, José Ramón Arribas, José A. Esté & José María Kindelán. (2005) Nuevas dianas y nuevos fármacos en el tratamiento de la infección por el VIH. Enfermedades Infecciosas y Microbiología Clínica 23, pages 25-32.
Crossref
Crossref
Tanja N Hartmann, Jan A Burger, Aleksandra Glodek, Nobutaka Fujii & Meike Burger. (2005) CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells. Oncogene 24:27, pages 4462-4471.
Crossref
Crossref
Hirokazu TamamuraTakanobu ArakiSatoshi UedaZixuan WangShinya OishiAi EsakaJohn O. TrentHideki NakashimaNaoki YamamotoStephen C. PeiperAkira OtakaNobutaka Fujii. (2005) Identification of Novel Low Molecular Weight CXCR4 Antagonists by Structural Tuning of Cyclic Tetrapeptide Scaffolds. Journal of Medicinal Chemistry 48:9, pages 3280-3289.
Crossref
Crossref
Hirokazu Tamamura, Kenichi Hiramatsu, Satoshi Ueda, Zixuan Wang, Shuichi Kusano, Shigemi Terakubo, John O. Trent, Stephen C. Peiper, Naoki Yamamoto, Hideki Nakashima, Akira Otaka & Nobutaka Fujii. (2004)
Stereoselective Synthesis of [
l
-Arg-
l
/
d
-3-(2-naphthyl)alanine]-Type (
E
)-Alkene Dipeptide Isosteres and Its Application to the Synthesis and Biological Evaluation of Pseudopeptide Analogues of the CXCR4 Antagonist FC131
. Journal of Medicinal Chemistry 48:2, pages 380-391.
Crossref
Crossref
V. I. Kulinsky & L. S. Kolesnichenko. (2005) Molecular mechanisms of hormonal activity. I. receptors. neuromediators. systems with second messengers. Biochemistry (Moscow) 70:1, pages 24-39.
Crossref
Crossref
V. I. Kulinsky & L. S. Kolesnichenko. (2005) Molecular mechanisms of hormonal activity. I. receptors. neuromediators. systems with second messengers. Biochemistry (Moscow) 70:1, pages 24-39.
Crossref
Crossref
V. I. Kulinsky & L. S. Kolesnichenko. (2005) Molecular mechanisms of hormonal activity. I. receptors. neuromediators. systems with second messengers. Biochemistry (Moscow) 70:1, pages 24-39.
Crossref
Crossref
Takashi Murakami, Adela R. Cardones & Sam T. Hwang. (2004) Chemokine receptors and melanoma metastasis. Journal of Dermatological Science 36:2, pages 71-78.
Crossref
Crossref
M Takenaga, H Tamamura, K Hiramatsu, N Nakamura, Y Yamaguchi, A Kitagawa, S Kawai, H Nakashima, N Fujii & R Igarashi. (2004) A single treatment with microcapsules containing a CXCR4 antagonist suppresses pulmonary metastasis of murine melanoma. Biochemical and Biophysical Research Communications 320:1, pages 226-232.
Crossref
Crossref
Farida Shaheen & Ronald G. Collman. (2004) Co-receptor antagonists as HIV-1 entry inhibitors. Current Opinion in Infectious Diseases 17:1, pages 7-16.
Crossref
Crossref
Jean-Michel Daoudi, Jacques Greiner, Anne-Marie Aubertin & Pierre Vierling. (2004) New bicyclam–GalCer analogue conjugates: synthesis and in vitro anti-HIV activity. Bioorganic & Medicinal Chemistry Letters 14:2, pages 495-498.
Crossref
Crossref
Qian Zhao, Hong Lu, Dominique Schols, Erik De Clercq & Shibo Jiang. (2003) Development of a Cell-Based Enzyme-Linked Immunosorbent Assay for High-Throughput Screening of HIV Type 1 Entry Inhibitors Targeting the Coreceptor CXCR4. AIDS Research and Human Retroviruses 19:11, pages 947-955.
Crossref
Crossref
Stefan Fruehauf & Ruth Seggewiss. (2003) It's moving day: factors affecting peripheral blood stem mobilization and strategies for improvement. British Journal of Haematology 122:3, pages 360-375.
Crossref
Crossref
Erik De Clercq. (2003) The bicyclam AMD3100 story. Nature Reviews Drug Discovery 2:7, pages 581-587.
Crossref
Crossref
Santa Jeremy Ono, Takao Nakamura, Dai Miyazaki, Masaharu Ohbayashi, Maria Dawson & Masako Toda. (2003) Chemokines: Roles in leukocyte development, trafficking, and effector function. Journal of Allergy and Clinical Immunology 111:6, pages 1185-1199.
Crossref
Crossref