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Expert Opinion on Investigational Drugs Volume 14, 2005 - Issue 12
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Drug Evaluation

The protein kinase C-β inhibitor, ruboxistaurin, for the treatment of diabetic microvascular complications

Aaron Vinik The Strelitz Diabetes Institute, Eastern Virginia Medical School, 855 West Brambleton Avenue, Norfolk, VA 23510, USA. [email protected]
Pages 1547-1559 | Published online: 25 Nov 2005

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Nikolaos Papanas & Dan Ziegler. (2016) Emerging drugs for diabetic peripheral neuropathy and neuropathic pain. Expert Opinion on Emerging Drugs 21:4, pages 393-407.
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Joydip Das. (2016) Novel N-pyrimidin-4-yl-3-amino-pyrrolo [3, 4-C] pyrazole derivatives as PKC kinase inhibitors: a patent evaluation of US2015099743 (A1). Expert Opinion on Therapeutic Patents 26:4, pages 523-528.
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Articles from other publishers (12)

Simran, Amarjot Kaur Grewal, Sandeep Arora & Thakur Gurjeet Singh. (2019) Role of Protein Kinase C in Diabetic Complications. Journal of Pharmaceutical Technology, Research and Management 7:2, pages 87-95.
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Abdullah Mayati, Amélie Moreau, Marc Le Vée, Bruno Stieger, Claire Denizot, Yannick Parmentier & Olivier Fardel. (2017) Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression. International Journal of Molecular Sciences 18:4, pages 764.
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Yanan Liu, Jiqin Jin, Shigang Qiao, Shaoqing Lei, Songyan Liao, Zhi-Dong GeHaobo Li, Gordon Tin-chun Wong, Michael G. Irwin & Zhengyuan Xia. (2015) Inhibition of PKCβ2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling. Clinical Science 129:4, pages 331-344.
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Joungil Choi, Krish Chandrasekaran, Tatsuya Inoue, Anjaneyulu Muragundla & James W. Russell. (2014) PGC-1α regulation of mitochondrial degeneration in experimental diabetic neuropathy. Neurobiology of Disease 64, pages 118-130.
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Stephan Grant, Phong Tran, Qin Zhang, Aihua Zou, Dac Dinh, Jordan Jensen, Sue Zhou, Xiaolin Kang, Joseph Zachwieja, John Lippincott, Kevin Liu, Sarah Ludlum Johnson, Stephanie Scales, Chunfeng Yin, Seiji Nukui, Chad Stoner, Ganesh Prasanna, Jennifer Lafontaine, Peter Wells & Hui Li. (2010) Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model. European Journal of Pharmacology 627:1-3, pages 16-25.
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Elena Osto & Francesco Cosentino. 2010. Nitric Oxide. Nitric Oxide 705 754 .
Elena OstoAlexei KouroedovPavani MocharlaAlexander AkhmedovChristian BeslerLucia RohrerArnold von EckardsteinSabino IlicetoMassimo VolpeThomas F. LüscherFrancesco Cosentino. (2008) Inhibition of Protein Kinase Cβ Prevents Foam Cell Formation by Reducing Scavenger Receptor A Expression in Human Macrophages. Circulation 118:21, pages 2174-2182.
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Jacek P. Szaflik, Ireneusz Majsterek, Michal Kowalski, Pawel Rusin, Anna Sobczuk, Anna I. Borucka, Jerzy Szaflik & Janusz Blasiak. (2008) Association between sorbitol dehydrogenase gene polymorphisms and type 2 diabetic retinopathy. Experimental Eye Research 86:4, pages 647-652.
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B. Vergès. (2008) FIELD deux ans après : quelle place pour les fibrates dans le diabète de type 2 ?. Médecine des Maladies Métaboliques 2:1, pages 32-37.
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V. Durlach. (2008) Dyslipidémie et complications micro-angiopathiques du diabète sucré. Médecine des Maladies Métaboliques 2:1, pages 23-27.
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Bernardo Léo Wajchenberg. (2007) Postprandial glycemia and cardiovascular disease in diabetes mellitus. Arquivos Brasileiros de Endocrinologia & Metabologia 51:2, pages 212-221.
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Mark E Williams. (2006) New Potential Agents in Treating Diabetic Kidney Disease. Drugs 66:18, pages 2287-2298.
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