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Review

Inhibitors of the mammalian target of rapamycin

Pages 313-328 | Published online: 22 Apr 2005

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Robert Amato & Mika Stepankiw. (2013) Evaluation of everolimus in renal cell cancer. Expert Opinion on Pharmacotherapy 14:9, pages 1229-1240.
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Putao Cen & Robert J Amato. (2012) Treatment of advanced pancreatic neuroendocrine tumors: potential role of everolimus. OncoTargets and Therapy 5, pages 217-224.
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David Neal Franz. (2011) Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis. Expert Review of Anticancer Therapy 11:8, pages 1181-1192.
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Robert Amato. (2011) Everolimus for the treatment of advanced renal cell carcinoma. Expert Opinion on Pharmacotherapy 12:7, pages 1143-1155.
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Angela M Liu, Michelle Z Xu, Jinfei Chen, Ronnie T Poon & John M Luk. (2010) Targeting YAP and Hippo signaling pathway in liver cancer. Expert Opinion on Therapeutic Targets 14:8, pages 855-868.
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Gerhard Treiber. (2009) mTOR inhibitors for hepatocellular cancer: a forward-moving target. Expert Review of Anticancer Therapy 9:2, pages 247-261.
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Olivia Aranha & Mark Agulnik. (2008) Molecularly targeted therapies in adult soft tissue sarcomas: present approach and future directions. Expert Opinion on Therapeutic Targets 12:2, pages 197-207.
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Angiolo Gadducci, Roberta Tana, Stefania Cosio, Antonio Fanucchi & Andrea Riccardo Genazzani. (2008) Molecular target therapies in endometrial cancer: From the basic research to the clinic. Gynecological Endocrinology 24:5, pages 239-249.
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Hanne Hagland, Julie Nikolaisen, Linn I Hodneland, Bjøorn T Gjertsen, Øystein Bruserud & Karl J Tronstad. (2007) Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling. Expert Opinion on Therapeutic Targets 11:8, pages 1055-1069.
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Angiolo Gadducci, Stefania Cosio & Andrea Riccardo Genazzani. (2007) Novel targeted therapies in epithelial ovarian cancer: from basic research to the clinic. Expert Review of Endocrinology & Metabolism 2:2, pages 225-238.
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Luis Fayad & Anas Younes. (2006) Novel treatment strategies for aggressive non-Hodgkin’s lymphoma. Expert Opinion on Pharmacotherapy 7:6, pages 733-748.
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Georgios V Georgakis & Anas Younes. (2006) From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy. Expert Review of Anticancer Therapy 6:1, pages 131-140.
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Lauren J. Akers, Wendy Fang, Alejandro G. Levy, Anna R. Franklin, Peng Huang & Patrick A. Zweidler-McKay. (2011) Targeting glycolysis in leukemia: A novel inhibitor 3-BrOP in combination with rapamycin. Leukemia Research 35:6, pages 814-820.
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Ki-Hwan Eum & Michael Lee. (2011) Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells. Molecules and Cells 31:3, pages 231-238.
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A. Cataneo-Dávila, J. Zúñiga-Varga, R. Correa-Rotter & J. Alberú. (2009) Renal Function Outcomes in Kidney Transplant Recipients After Conversion to Everolimus-Based Immunosuppression Regimen with CNI Reduction or Elimination. Transplantation Proceedings 41:10, pages 4138-4146.
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Anthony Calabro, Julia Tai, Steven L. Allen & Daniel R. Budman. (2008) In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia. Anti-Cancer Drugs 19:7, pages 705-712.
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Jorge A. Garcia & David Danielpour. (2008) Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. Molecular Cancer Therapeutics 7:6, pages 1347-1354.
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Josep Tabernero, Federico Rojo, Emiliano Calvo, Howard Burris, Ian Judson, Katharine Hazell, Erika Martinelli, Santiago Ramon y Cajal, Suzanne Jones, Laura Vidal, Nicholas Shand, Teresa Macarulla, Francisco Javier Ramos, Sasa Dimitrijevic, Ulrike Zoellner, Pui Tang, Michael Stumm, Heidi A. Lane, David Lebwohl & José Baselga. (2008) Dose- and Schedule-Dependent Inhibition of the Mammalian Target of Rapamycin Pathway With Everolimus: A Phase I Tumor Pharmacodynamic Study in Patients With Advanced Solid Tumors. Journal of Clinical Oncology 26:10, pages 1603-1610.
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