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Editorial

Complementary new approaches enable repositioning of failed drug candidates

Pages 1295-1298 | Published online: 16 Oct 2006

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Vittavat Termglinchan, Wachiraporn Wanichnopparat, Kulachanya Suwanwongse, Chunhakarn Teeyapant, Kanticha Chatpermporn, Kanchana Leerunyakul, Khwanruthai Chuadpia, Onpailin Sirimaneethum, Parinya Wijitworawong, Wattanakitch Mutirangura, Chatchawit Aporntewan, Chanida Vinayanuwattikun & Apiwat Mutirangura. (2013) Candidate cancer-targeting agents identified by expression-profiling arrays. OncoTargets and Therapy 6, pages 447-458.
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Yuanchun Zhao, Xingqi Chen, Jiajia Chen & Xin Qi. (2023) Decoding Connectivity Map-based drug repurposing for oncotherapy. Briefings in Bioinformatics 24:3.
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Nithya Krishnamurthy, Alyssa A. Grimshaw, Sydney A. Axson, Sung Hee Choe & Jennifer E. Miller. (2022) Drug repurposing: a systematic review on root causes, barriers and facilitators. BMC Health Services Research 22:1.
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Theodora Katsila, Styliani A. Chasapi, Jose Carlos Gomez Tamayo, Constantina Chalikiopoulou, Eleni Siapi, Giorgos Moros, Panagiotis Zoumpoulakis, Georgios A. Spyroulias & Dimitrios Kardamakis. (2021) Three-Dimensional Cell Metabolomics Deciphers the Anti-Angiogenic Properties of the Radioprotectant Amifostine. Cancers 13:12, pages 2877.
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Derek B. Oien, Christopher L. Pathoulas, Upasana Ray, Prabhu Thirusangu, Eleftheria Kalogera & Viji Shridhar. (2021) Repurposing quinacrine for treatment-refractory cancer. Seminars in Cancer Biology 68, pages 21-30.
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Arun Balasubramaniam, Prakoso Adi, Do Thi Tra My, Sunita Keshari, Raman Sankar, Chien-Lung Chen & Chun-Ming Huang. (2020) Repurposing INCI-registered compounds as skin prebiotics for probiotic Staphylococcus epidermidis against UV-B. Scientific Reports 10:1.
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Justin Bauzon, Garam Lee & Jeffrey Cummings. (2020) Repurposed agents in the Alzheimer’s disease drug development pipeline. Alzheimer's Research & Therapy 12:1.
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Michel Montalvo-Casimiro, Rodrigo González-Barrios, Marco Antonio Meraz-Rodriguez, Vasti Thamara Juárez-González, Cristian Arriaga-Canon & Luis A. Herrera. (2020) Epidrug Repurposing: Discovering New Faces of Old Acquaintances in Cancer Therapy. Frontiers in Oncology 10.
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Akeem A. Ayankunle, Olayemi K. Wakeel, Oyetunji T. Kolawole, Adesola O. Oyekale, Olusola Ojurongbe & Oluwaseyi A. Adeyeba. (2020) Drug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with Plasmodium berghei. Central Nervous System Agents in Medicinal Chemistry 20:2, pages 110-121.
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Ritesh Thakare, Manjulika Shukla, Grace Kaul, Arunava Dasgupta & Sidharth Chopra. (2019) Repurposing disulfiram for treatment of Staphylococcus aureus infections. International Journal of Antimicrobial Agents 53:6, pages 709-715.
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Kyriaki Savva, Margarita Zachariou, Anastasis Oulas, George Minadakis, Kleitos Sokratous, Nikolas Dietis & George M. Spyrou. 2019. In Silico Drug Design. In Silico Drug Design 85 118 .
Tao Wang, Hai-Cheng Yi, Zhu-Hong You, Li-Ping Li, Yan-Bin Wang, Lun Hu & Leon Wong. 2019. Intelligent Computing Theories and Application. Intelligent Computing Theories and Application 344 353 .
Ladislav Peska, Krisztian Buza & Júlia Koller. (2017) Drug-target interaction prediction: A Bayesian ranking approach. Computer Methods and Programs in Biomedicine 152, pages 15-21.
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Ritesh Thakare, Alok Kumar Singh, Swetarka Das, N. Vasudevan, Gorakhnath R. Jachak, D. Srinivasa Reddy, Arunava Dasgupta & Sidharth Chopra. (2017) Repurposing Ivacaftor for treatment of Staphylococcus aureus infections. International Journal of Antimicrobial Agents 50:3, pages 389-392.
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D. Cavalla, E. Oerton & A. Bender. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 11 47 .
Remya Ramesh, Rahul D. Shingare, Vinod Kumar, Amitesh Anand, Swetha B, Sridhar Veeraraghavan, Srikant Viswanadha, Ramesh Ummanni, Rajesh Gokhale & D. Srinivasa Reddy. (2016) Repurposing of a drug scaffold: Identification of novel sila analogues of rimonabant as potent antitubercular agents. European Journal of Medicinal Chemistry 122, pages 723-730.
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Holly Matthews, Maryam Usman-Idris, Farid Khan, Martin Read & Niroshini Nirmalan. (2013) Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate. Malaria Journal 12:1.
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Francesco Iorio, Timothy Rittman, Hong Ge, Michael Menden & Julio Saez-Rodriguez. (2013) Transcriptional data: a new gateway to drug repositioning?. Drug Discovery Today 18:7-8, pages 350-357.
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Michael S. Saporito, Christopher A. Lipinski & Andrew G. Reaume. 2012. Drug Repositioning. Drug Repositioning 253 290 .
John Arrowsmith & Richard Harrison. 2012. Drug Repositioning. Drug Repositioning 7 32 .
Kim Henriksen, Claus Christiansen & Morten Asser Karsdal. (2011) Serological biochemical markers of surrogate efficacy and safety as a novel approach to drug repositioning. Drug Discovery Today 16:21-22, pages 967-975.
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Heng Luo, Jian Chen, Leming Shi, Mike Mikailov, Huang Zhu, Kejian Wang, Lin He & Lun Yang. (2011) DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome. Nucleic Acids Research 39:suppl_2, pages W492-W498.
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S. J. Swamidass. (2011) Mining small-molecule screens to repurpose drugs. Briefings in Bioinformatics 12:4, pages 327-335.
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V. J. Haupt & M. Schroeder. (2011) Old friends in new guise: repositioning of known drugs with structural bioinformatics. Briefings in Bioinformatics 12:4, pages 312-326.
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Irene Seunghyun Hong, Heather J Ipema, Michael P Gabay & Amy E Lodolce. (2011) Medication Repurposing: New Uses for Old Drugs. Journal of Pharmacy Technology 27:3, pages 132-140.
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Hirotaka Inoue & Shu Yamada. (2010) Failure mode and effects analysis in pharmaceutical research. International Journal of Quality and Service Sciences 2:3, pages 369-382.
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Dmitry Filimonov & Vladimir Poroikov. 2008. Chemoinformatics Approaches to Virtual Screening. Chemoinformatics Approaches to Virtual Screening 182 216 .
Doreen Alberts. (2008) The ever-changing role of information professionals in pharmaceutical R&D. World Patent Information 30:3, pages 233-237.
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David Borsook, David Bleakman, Richard Hargreaves, Jaymin Upadhyay, Karl F. Schmidt & Lino Becerra. (2008) A ‘BOLD’ experiment in defining the utility of fMRI in drug development. NeuroImage 42:2, pages 461-466.
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Ulrich Nielsch, Stefan Schäfer, Hanno Wild & Andreas Busch. (2007) One target–multiple indications: a call for an integrated common mechanisms strategy. Drug Discovery Today 12:23-24, pages 1025-1031.
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