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Review

Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia

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Pages 1337-1351 | Published online: 16 Oct 2006

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Binh An P Phan, Thomas D Dayspring & Peter P Toth. (2012) Ezetimibe therapy: mechanism of action and clinical update. Vascular Health and Risk Management 8, pages 415-427.
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Harold E Bays, David Neff, Joanne E Tomassini & Andrew M Tershakovec. (2008) Ezetimibe: cholesterol lowering and beyond. Expert Review of Cardiovascular Therapy 6:4, pages 447-470.
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John R Burnett & Gerald F Watts. (2007) MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises?. Expert Opinion on Therapeutic Targets 11:2, pages 181-189.
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Articles from other publishers (17)

Renshuai Zhang, Wenjing Liu, Jun Zeng, Jingsen Meng, Hongfei Jiang, Jie Wang & Dongming Xing. (2022) Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption. European Journal of Medicinal Chemistry 230, pages 114111.
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Hsin-Pei Shih, Xiaodan Zhang & Alex M. Aronov. (2017) Drug discovery effectiveness from the standpoint of therapeutic mechanisms and indications. Nature Reviews Drug Discovery 17:1, pages 19-33.
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Zhourong Ruan, Bo jiang, Jinliang Chen, Xuehua Zhang, Honggang Lou, Meixiang Xiang, Qingxiang Shao & Jian'an Wang. (2014) Pharmacokinetics, pharmacodynamics, safety, and tolerability of hyzetimibe (HS-25) in healthy Chinese subjects. The Journal of Clinical Pharmacology 54:10, pages 1144-1152.
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Dorothy Nulty. (2013) Knee pain: An unanticipated finding related to a rare genetic disorder-Abetalipoproteinemia. Journal of the American Association of Nurse Practitioners 25:6, pages 297-301.
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Richard G. Lee, Wuxia Fu, Mark J. Graham, Adam E. Mullick, Donna Sipe, Danielle Gattis, Thomas A. Bell, Sheri Booten & Rosanne M. Crooke. (2013) Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein. Journal of Lipid Research 54:3, pages 602-614.
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Shu-Long Yao, Ying Xu, Yan-Yan Zhang & Yan-Hua Lu. (2013) Black rice and anthocyanins induce inhibition of cholesterol absorption in vitro. Food & Function 4:11, pages 1602.
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Andrew Tonkin, David Hunt, Merryn Voysey, Antero Kesäniemi, Andrew Hamer, Jonathon Waites, Leo Mahar, Stewart Mann, Paul Glasziou, Peta Forder, John Simes & Anthony C. Keech. (2012) Effects of fenofibrate on cardiovascular events in patients with diabetes, with and without prior cardiovascular disease: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. American Heart Journal 163:3, pages 508-514.
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Shayne Cox GadStefan Oswald & Werner Siegmund. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Tappei Takada & Hiroshi Suzuki. (2010) Molecular mechanisms of membrane transport of vitamin E. Molecular Nutrition & Food Research 54:5, pages 616-622.
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J. Méndez-González, S. Süren-Castillo, L. Calpe-Berdiel, N. Rotllan, M. Vázquez-Carrera, J. C. Escolà-Gil & F. Blanco-Vaca. (2009) Disodium ascorbyl phytostanol phosphate (FM-VP4), a modified phytostanol, is a highly active hypocholesterolaemic agent that affects the enterohepatic circulation of both cholesterol and bile acids in mice. British Journal of Nutrition 103:2, pages 153-160.
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G. Misinzo, P.L. Delputte, D.J. Lefebvre & H.J. Nauwynck. (2009) Porcine circovirus 2 infection of epithelial cells is clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated, and enhanced by cholesterol depletion. Virus Research 139:1, pages 1-9.
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Dinko Susic, Xiaoyan Zhou, Edward D. Frohlich, Howard Lippton & Martha Knight. (2008) Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet. American Journal of Physiology-Heart and Circulatory Physiology 295:3, pages H1117-H1121.
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Dawn E. Telford & Murray W. Huff. (2008) Postprandial hyperlipidemia: Cardiovascular implications and treatment options. Canadian Journal of Cardiology 24, pages 32C-37C.
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Anne Braun, Ayce Yesilaltay, Susan Acton, Kay O. Broschat, Elaine S. Krul, Nida Napawan, Nancy Stagliano & Monty Krieger. (2008) Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double knockout mice. Atherosclerosis 198:1, pages 77-84.
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Karim El Harchaoui, Fatima Akdim, Erik S G Stroes, Mieke D Trip & John J P Kastelein. (2008) Current and Future Pharmacologic Options for the Management of Patients Unable to Achieve Low-Density Lipoprotein-Cholesterol Goals with Statins. American Journal of Cardiovascular Drugs 8:4, pages 233-242.
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Jeffrey A. Pfefferkorn, Scott D. Larsen, Chad Van Huis, Roderick Sorenson, Tom Barton, Thomas Winters, Bruce Auerbach, Chenyan Wu, Thaddeus J. Wolfram, Hongliang Cai, Kathleen Welch, Nadia Esmaiel, JoAnn Davis, Richard Bousley, Karl Olsen, Sandra Bak Mueller & Thomas Mertz. (2008) Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption. Bioorganic & Medicinal Chemistry Letters 18:2, pages 546-553.
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David J. Newman, Gordon M. Cragg & David G. I. Kingston. 2008. The Practice of Medicinal Chemistry. The Practice of Medicinal Chemistry 159 186 .

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