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Expert Opinion on Investigational Drugs Volume 17, 2008 - Issue 10
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Review

Glycolytic enzyme inhibitors in cancer treatment

Roberto Scatena Catholic University, Department of Laboratory Medicine, Largo A. Gemelli 8, 00168 Rome, Italy +39 0 630 154 222; +39 0 635 501 918; [email protected]
,
Patrizia Bottoni Catholic University, Department of Laboratory Medicine, Largo A. Gemelli 8, 00168 Rome, Italy +39 0 630 154 222; +39 0 635 501 918; [email protected]
,
Alessandro Pontoglio Catholic University, Department of Laboratory Medicine, Largo A. Gemelli 8, 00168 Rome, Italy +39 0 630 154 222; +39 0 635 501 918; [email protected]
,
Lucia Mastrototaro Catholic University, Department of Laboratory Medicine, Largo A. Gemelli 8, 00168 Rome, Italy +39 0 630 154 222; +39 0 635 501 918; [email protected]
&
Bruno Giardina Catholic University, Department of Laboratory Medicine, Largo A. Gemelli 8, 00168 Rome, Italy +39 0 630 154 222; +39 0 635 501 918; [email protected]
Pages 1533-1545 | Published online: 22 Sep 2008

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Qi Tan, Limin Duan, Qi Huang, Wenjuan Chen, Zimo Yang, Jiangbin Chen & Yang Jin. (2021) Interleukin -1β Promotes Lung Adenocarcinoma Growth and Invasion Through Promoting Glycolysis via p38 Pathway. Journal of Inflammation Research 14, pages 6491-6509.
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Shanmugasundaram Ganapathy-Kanniappan. (2018) Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype. Critical Reviews in Biochemistry and Molecular Biology 53:6, pages 667-682.
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Ramon Bartrons, Ana Rodríguez-García, Helga Simon-Molas, Esther Castaño, Anna Manzano & Àurea Navarro-Sabaté. (2018) The potential utility of PFKFB3 as a therapeutic target. Expert Opinion on Therapeutic Targets 22:8, pages 659-674.
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Michael Mouradian, Irvin V. Ma, Erika D. Vicente, Keith D. Kikawa & Ronald S. Pardini. (2017) Docosahexaenoic Acid-mediated Inhibition of Heat Shock Protein 90-p23 Chaperone Complex and Downstream Client Proteins in Lung and Breast Cancer. Nutrition and Cancer 69:1, pages 92-104.
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Gireedhar Venkatachalam, Alan Prem Kumar, Kishore R. Sakharkar, Sindhu Thangavel, Marie-Véronique Clement & Meena Kishore Sakharkar. (2011) PPARγ disease gene network and identification of therapeutic targets for prostate cancer. Journal of Drug Targeting 19:9, pages 781-796.
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Lidong Cao, Jiacheng Wu, Xianzhi Qu, Jiyao Sheng, Mengying Cui, Shui Liu, Xu Huang, Yien Xiang, Bingjin Li, Xuewen Zhang & Ranji Cui. (2020) Glycometabolic rearrangements--aerobic glycolysis in pancreatic cancer: causes, characteristics and clinical applications. Journal of Experimental & Clinical Cancer Research 39:1.
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Peng Yuan, Tao Yang, Jiao Mu, Jing Zhao, Yi Yang, Zhaoyong Yan, Yiran Hou, Cheng Chen, Jinliang Xing, Hongxin Zhang & Jibin Li. (2020) Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cells. Cancer Letters 469, pages 498-509.
Crossref
Amarjeet Shrama, Priyanshi & Chandi C. Mandal. 2020. Pharmacotherapeutic Botanicals for Cancer Chemoprevention. Pharmacotherapeutic Botanicals for Cancer Chemoprevention 143 165 .
Francesca Paganelli, Annalisa Lonetti, Laura Anselmi, Alberto M. Martelli, Camilla Evangelisti & Francesca Chiarini. (2019) New advances in targeting aberrant signaling pathways in T-cell acute lymphoblastic leukemia. Advances in Biological Regulation 74, pages 100649.
Crossref
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Crossref
Jianwei Li, Fang Wang, Hongzhi Gao, Sihuai Huang, Fangzhen Cai & Jianguo Sun. (2019) ALDOLASE A regulates invasion of bladder cancer cells via E‐cadherin‐EGFR signaling. Journal of Cellular Biochemistry 120:8, pages 13694-13705.
Crossref
Qingqing Wei, Jennifer Su, Guie Dong, Ming Zhang, Yuqing Huo & Zheng Dong. (2019) Glycolysis inhibitors suppress renal interstitial fibrosis via divergent effects on fibroblasts and tubular cells. American Journal of Physiology-Renal Physiology 316:6, pages F1162-F1172.
Crossref
Tiago MA. Carvalho, Henrique J. Cardoso, Marília I. Figueira, Cátia V. Vaz & Sílvia Socorro. (2019) The peculiarities of cancer cell metabolism: A route to metastasization and a target for therapy. European Journal of Medicinal Chemistry 171, pages 343-363.
Crossref
Diksha Sharma, Kushal K. Bansal, Archana Sharma, Meenakshi Pathak & Prabodh C. Sharma. (2019) A Brief Literature and Review of Patents on Thiazole Related Derivatives. Current Bioactive Compounds 15:3, pages 304-315.
Crossref
Louis W. C. Chow, Ka-Shun Cheng, Fai Leong, Chi-Wai Cheung, Lian-Ru Shiao, Yuk-Man Leung & Kar-Lok Wong. (2018) Enhancing tetrandrine cytotoxicity in human lung carcinoma A549 cells by suppressing mitochondrial ATP production. Naunyn-Schmiedeberg's Archives of Pharmacology 392:4, pages 427-436.
Crossref
Tengjiao Fan, Guohui Sun, Xiaodong Sun, Lijiao Zhao, Rugang Zhong & Yongzhen Peng. (2019) Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment. Cancers 11:3, pages 317.
Crossref
Hyo Young Jung, Hyun Jung Kwon, Woosuk Kim, Sung Min Nam, Jong Whi Kim, Kyu Ri Hahn, Dae Young Yoo, Moo-Ho Won, Yeo Sung Yoon, Dae Won Kim & In Koo Hwang. (2018) Phosphoglycerate Mutase 1 Promotes Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus by Facilitating the Phosphorylation of cAMP Response Element-Binding Protein. Neurochemical Research 44:2, pages 323-332.
Crossref
Patrizia Bottoni & Roberto Scatena. 2019. Mitochondria in Health and in Sickness. Mitochondria in Health and in Sickness 1 16 .
Angela R. Guerra, Maria F. Duarte & Iola F. Duarte. (2018) Targeting Tumor Metabolism with Plant-Derived Natural Products: Emerging Trends in Cancer Therapy. Journal of Agricultural and Food Chemistry 66:41, pages 10663-10685.
Crossref
Ramon Bartrons, Helga Simon-Molas, Ana Rodríguez-García, Esther Castaño, Àurea Navarro-Sabaté, Anna Manzano & Ubaldo E. Martinez-Outschoorn. (2018) Fructose 2,6-Bisphosphate in Cancer Cell Metabolism. Frontiers in Oncology 8.
Crossref
Yu-Chan Chang, Yi-Chieh Yang, Chia-Ping Tien, Chih-Jen Yang & Michael Hsiao. (2018) Roles of Aldolase Family Genes in Human Cancers and Diseases. Trends in Endocrinology & Metabolism 29:8, pages 549-559.
Crossref
Jessica L. Counihan, Elizabeth A. Grossman & Daniel K. Nomura. (2018) Cancer Metabolism: Current Understanding and Therapies. Chemical Reviews 118:14, pages 6893-6923.
Crossref
Juan M. Hernández-Meza & José G. Sampedro. (2018) Trehalose Mediated Inhibition of Lactate Dehydrogenase from Rabbit Muscle. The Application of Kramers’ Theory in Enzyme Catalysis. The Journal of Physical Chemistry B 122:15, pages 4309-4317.
Crossref
Peter Hofmann. (2018) Cancer and Exercise: Warburg Hypothesis, Tumour Metabolism and High-Intensity Anaerobic Exercise. Sports 6:1, pages 10.
Crossref
Marco De Vivo, Matteo Masetti & Giulia Rossetti. 2017. Computational Tools for Chemical Biology. Computational Tools for Chemical Biology 317 348 .
Nusrat Chowdhury, Imran Vhora, Ketan Patel, Ravi Doddapaneni, Arindam Mondal & Mandip Singh. (2017) Liposomes co-Loaded with 6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3 (PFKFB3) shRNA Plasmid and Docetaxel for the Treatment of non-small Cell Lung Cancer. Pharmaceutical Research 34:11, pages 2371-2384.
Crossref
D Maciaczyk, D Picard, L Zhao, K Koch, D Herrera-Rios, G Li, V Marquardt, D Pauck, T Hoerbelt, W Zhang, D M Ouwens, M Remke, T Jiang, H J Steiger, J Maciaczyk & U D Kahlert. (2017) CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells. British Journal of Cancer 117:1, pages 102-112.
Crossref
Shanmugasundaram Ganapathy-Kanniappan. (2017) Taming Tumor Glycolysis and Potential Implications for Immunotherapy. Frontiers in Oncology 7.
Crossref
Ryan Reyes, Nissar A. Wani, Kalpana Ghoshal, Samson T. Jacob & Tasneem Motiwala. (2017) Sorafenib and 2-Deoxyglucose Synergistically Inhibit Proliferation of Both Sorafenib-Sensitive and -Resistant HCC Cells by Inhibiting ATP Production. Gene Expression 17:2, pages 129-140.
Crossref
Mohadeseh Hasanpourghadi, Chandrabose Karthikeyan, Ashok Kumar Pandurangan, Chung Yeng Looi, Piyush Trivedi, Kinue Kobayashi, Kozo Tanaka, Won Fen Wong & Mohd Rais Mustafa. (2016) Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell. Journal of Experimental & Clinical Cancer Research 35:1.
Crossref
Annegret Kathagen-Buhmann, Alexander Schulte, Jonathan Weller, Mareike Holz, Christel Herold-Mende, Rainer Glass & Katrin Lamszus. (2016) Glycolysis and the pentose phosphate pathway are differentially associated with the dichotomous regulation of glioblastoma cell migration versus proliferation. Neuro-Oncology 18:9, pages 1219-1229.
Crossref
Geoffrey Grandjean, Petrus R. de Jong, Brian P. James, Mei Yee Koh, Robert Lemos, John Kingston, Alexander Aleshin, Laurie A. Bankston, Claudia P. Miller, Eun Jeong Cho, Ramakrishna Edupuganti, Ashwini Devkota, Gabriel Stancu, Robert C. Liddington, Kevin N. Dalby & Garth Powis. (2016) Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target. Cancer Research 76:14, pages 4259-4269.
Crossref
Denis Voronin, Saheed Bachu, Michael Shlossman, Thomas R. Unnasch, Elodie Ghedin & Sara Lustigman. (2016) Glucose and Glycogen Metabolism in Brugia malayi Is Associated with Wolbachia Symbiont Fitness. PLOS ONE 11:4, pages e0153812.
Crossref
Shunrong Ji, Bo Zhang, Jiang Liu, Yi Qin, Chen Liang, Si Shi, Kaizhou Jin, Dingkong Liang, Wenyan Xu, Huaxiang Xu, Wenquan Wang, Chuntao Wu, Liang Liu, Chen Liu, Jin Xu, Quanxing Ni & Xianjun Yu. (2016) ALDOA functions as an oncogene in the highly metastatic pancreatic cancer. Cancer Letters 374:1, pages 127-135.
Crossref
Anthony KC Chan, Jason IE Bruce & Ajith K Siriwardena. (2016) Glucose metabolic phenotype of pancreatic cancer. World Journal of Gastroenterology 22:12, pages 3471-3485.
Crossref
Hugh Billings, Suzanne M Crowe & Clovis S Palmer. (2016) Does immunometabolism provide new targets to treat HIV-mediated inflammatory diseases?. Future Virology 11:3, pages 159-162.
Crossref
D. A. Korshunov & I. V. Kondakova. Effect of anti-glycolytic agents on tumour cells in vitro. Effect of anti-glycolytic agents on tumour cells in vitro.
Sebastiano Rupiani, Laura Guidotti, Marcella Manerba, Lorenza Di Ianni, Elisa Giacomini, Federico Falchi, Giuseppina Di Stefano, Marinella Roberti & Maurizio Recanatini. (2016) Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A. Organic & Biomolecular Chemistry 14:46, pages 10981-10987.
Crossref
Vasilij Koshkin, Laurie E. Ailles, Geoffrey Liu & Sergey N. Krylov. (2016) Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells. Journal of Cellular Biochemistry 117:1, pages 59-65.
Crossref
Sebastiano Rupiani, Rosa Buonfiglio, Marcella Manerba, Lorenza Di Ianni, Marina Vettraino, Elisa Giacomini, Matteo Masetti, Federico Falchi, Giuseppina Di Stefano, Marinella Roberti & Maurizio Recanatini. (2015) Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors. European Journal of Medicinal Chemistry 101, pages 63-70.
Crossref
Krystal A. Fontaine, Erica L. Sanchez, Roman Camarda & Michael Lagunoff. (2015) Dengue Virus Induces and Requires Glycolysis for Optimal Replication. Journal of Virology 89:4, pages 2358-2366.
Crossref
Massimiliano Cazzaniga & Bernardo Bonanni. (2015) Breast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with Metformin. BioMed Research International 2015, pages 1-9.
Crossref
Rob C. Laister, Mark D. Minden & Tak W. Mak. 2015. Targeted Therapy of Acute Myeloid Leukemia. Targeted Therapy of Acute Myeloid Leukemia 709 723 .
Yong-Cheng Li. (2014) Enhanced cephalotaxine production in Cephalotaxus mannii suspension cultures by combining glycometabolic regulation and elicitation. Process Biochemistry 49:12, pages 2279-2284.
Crossref
Yong-Cheng Li, Xuan-Xian Jiang & Xiao-Juan Long. (2014) Effects and action mechanisms of sodium fluoride (NaF) on the growth and cephalotaxine production of Cephalotaxus mannii suspension cells. Enzyme and Microbial Technology 67, pages 77-81.
Crossref
Gek San Tan, Kiat Hon Lim, Hwee Tong Tan, May Lee Khoo, Sze Huey Tan, Han Chong Toh & Maxey Ching Ming Chung. (2014) Novel Proteomic Biomarker Panel for Prediction of Aggressive Metastatic Hepatocellular Carcinoma Relapse in Surgically Resectable Patients. Journal of Proteome Research 13:11, pages 4833-4846.
Crossref
Feng Long, Xinyan Cai, Wei Luo, Liang Chen & Kanghua Li. (2014) Role of aldolase A in osteosarcoma progression and metastasis: In vitro and in vivo evidence. Oncology Reports.
Crossref
Leonor Côrte-Real, Filipa Mendes, Joana Coimbra, Tânia S. Morais, Ana Isabel Tomaz, Andreia Valente, M. Helena Garcia, Isabel Santos, Manuel Bicho & Fernanda Marques. (2014) Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes. JBIC Journal of Biological Inorganic Chemistry 19:6, pages 853-867.
Crossref
Zhe-Yu Hu, Lanbo Xiao, Ann M. Bode, Zigang Dong & Ya Cao. (2014) Glycolytic genes in cancer cells are more than glucose metabolic regulators. Journal of Molecular Medicine 92:8, pages 837-845.
Crossref
Maud Privat, Nina Radosevic-Robin, Corinne Aubel, Anne Cayre, Frédérique Penault-Llorca, Geoffroy Marceau, Vincent Sapin, Yves-Jean Bignon & Daniel Morvan. (2014) BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells. PLoS ONE 9:7, pages e102438.
Crossref
YANG SUN, JIANHONG LONG & YU ZHOU. (2014) Angiopoietin-like 4 promotes melanoma cell invasion and survival through aldolase A. Oncology Letters 8:1, pages 211-217.
Crossref
Dong Ji, Zhong-Tang Lu, Yao-Qing Li, Zhe-Yong Liang, Peng-Fei Zhang, Chao Li, Jun-Li Zhang, Xin Zheng & Ying-Min Yao. (2014) MACC1 Expression Correlates with PFKFB2 and Survival in Hepatocellular Carcinoma. Asian Pacific Journal of Cancer Prevention 15:2, pages 999-1003.
Crossref
Cinzia Forni, Roberto Braglia, Nadia Mulinacci, Andrea Urbani, Maurizio Ronci, Angelo Gismondi, Claudio Tabolacci, Bruno Provenzano, Alessandro Lentini & Simone Beninati. (2014) Antineoplastic activity of strawberry (Fragaria ? ananassa Duch.) crude extracts on B16-F10 melanoma cells. Mol. BioSyst. 10:6, pages 1255-1263.
Crossref
M. Akram. (2013) Mini-review on Glycolysis and Cancer. Journal of Cancer Education 28:3, pages 454-457.
Crossref
J P Golding, T Wardhaugh, L Patrick, M Turner, J B Phillips, J I Bruce & S G Kimani. (2013) Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy. British Journal of Cancer 109:4, pages 976-982.
Crossref
Sanabria-Ayala V?ctor, Medina-Flores Yolanda, Zavala-Carballo Araceli, Jim?nez Luc?a & Landa Abraham. (2013) Characterization of a monoclonal antibody that specifically inhibits triosephosphate isomerase activity of Taenia solium. Experimental Parasitology 134:4, pages 495-503.
Crossref
Stephen Yiu Chuen Choi, Colin C Collins, Peter W Gout & Yuzhuo Wang. (2013) Cancer‐generated lactic acid: a regulatory, immunosuppressive metabolite?. The Journal of Pathology 230:4, pages 350-355.
Crossref
Saleha B. Vuyyuri, Jacob Rinkinen, Erin Worden, Hyekyung Shim, Sukchan Lee & Keith R. Davis. (2013) Ascorbic Acid and a Cytostatic Inhibitor of Glycolysis Synergistically Induce Apoptosis in Non-Small Cell Lung Cancer Cells. PLoS ONE 8:6, pages e67081.
Crossref
Sébastien Pomel & Philippe M. Loiseau. 2013. Trypanosomatid Diseases. Trypanosomatid Diseases 315 334 .
Annalisa Pacilli, Maria Calienni, Sabrina Margarucci, Maria D’Apolito, Orsolina Petillo, Laura Rocchi, Gianandrea Pasquinelli, Raffaella Nicolai, Aleardo Koverech, Menotti Calvani, Gianfranco Peluso & Lorenzo Montanaro. (2013) Carnitine-Acyltransferase System Inhibition, Cancer Cell Death, and Prevention of Myc-Induced Lymphomagenesis. JNCI: Journal of the National Cancer Institute 105:7, pages 489-498.
Crossref
Huasong Gao, Bin YuYaohua YanJianhong ShenSanhu Zhao, Jianhong Zhu, Wenxin QinYilu Gao. (2013) Correlation of expression levels of ANXA2, PGAM1, and CALR with glioma grade and prognosis. Journal of Neurosurgery 118:4, pages 846-853.
Crossref
Mohita Upadhyay, Jasmine Samal, Manish Kandpal, Om Vir Singh & Perumal Vivekanandan. (2013) The Warburg effect: Insights from the past decade. Pharmacology & Therapeutics 137:3, pages 318-330.
Crossref
Michalis G Kounelakis, Ekaterini S Bei, Michalis E Zervakis, Georgios C Giakos, Lin Zhang, Chaya Narayan & Dimitrios Kafetzopoulos. (2013) Measurement Methodologies for Assessing the Glycolysis Effect in the Discrimination and Therapy of Brain Gliomas. International Journal of Monitoring and Surveillance Technologies Research 1:1, pages 34-55.
Crossref
Anatoliy V. Popov & Leonid G. Menchikov. 2013. Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment. Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment 255 270 .
Sandipan Datta, Jun Li, Fakhri Mahdi, Mika B. Jekabsons, Dale G. Nagle & Yu-Dong Zhou. (2012) Glycolysis Inhibitor Screening Identifies the Bis-geranylacylphloroglucinol Protonophore Moronone from Moronobea coccinea . Journal of Natural Products 75:12, pages 2216-2222.
Crossref
Robert St.Onge, Ulrich Schlecht, Curt Scharfe & Marie Evangelista. (2012) Forward Chemical Genetics in Yeast for Discovery of Chemical Probes Targeting Metabolism. Molecules 17:11, pages 13098-13115.
Crossref
Carlotta Granchi & Filippo Minutolo. (2012) Anticancer Agents That Counteract Tumor Glycolysis. ChemMedChem 7:8, pages 1318-1350.
Crossref
Annamaria Rapisarda & Giovanni Melillo. (2012) Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia. Nature Reviews Clinical Oncology 9:7, pages 378-390.
Crossref
Christopher Auger, Varun Appanna, Zachary Castonguay, Sungwon Han & Vasu D. Appanna. (2012) A facile electrophoretic technique to monitor phosphoenolpyruvate‐dependent kinases. ELECTROPHORESIS 33:7, pages 1095-1101.
Crossref
Simona D'Aguanno, Igea D'Agnano, Michele De Canio, Claudia Rossi, Sergio Bernardini, Giorgio Federici & Andrea Urbani. (2012) Shotgun proteomics and network analysis of neuroblastoma cell lines treated with curcumin. Molecular BioSystems 8:4, pages 1068.
Crossref
Patrizia Bottoni, Bruno Giardina, Alessandro Pontoglio, Salvatore Scarà & Roberto Scatena. 2012. Advances in Mitochondrial Medicine. Advances in Mitochondrial Medicine 423 440 .
Roberto Scatena. 2012. Advances in Mitochondrial Medicine. Advances in Mitochondrial Medicine 287 308 .
Moïse Namer, Michel Héry, Marc Spielmann, Joseph Gligorov & Frédérique Penault-LlorcaK. Kerrou. 2012. Cancer du sein. Cancer du sein 257 275 .
Tao Yan, Kai Ove Skaftnesmo, Lina Leiss, Linda Sleire, Jian Wang, Xingang Li & Per Øyvind Enger. (2011) Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. BMC Cancer 11:1.
Crossref
Brijesh M. Madhok, Sashidhar Yeluri, Sarah L. Perry, Thomas A. Hughes & David G. Jayne. (2011) Targeting Glucose Metabolism. American Journal of Clinical Oncology 34:6, pages 628-635.
Crossref
Joanna Zawacka-Pankau, Vera V. Grinkevich, Sabine Hünten, Fedor Nikulenkov, Angela Gluch, Hai Li, Martin Enge, Alexander Kel & Galina Selivanova. (2011) Inhibition of Glycolytic Enzymes Mediated by Pharmacologically Activated p53. Journal of Biological Chemistry 286:48, pages 41600-41615.
Crossref
Kim Kultima, Karl Sköld & Mats Borén. (2011) Biomarkers of disease and post-mortem changes — Heat stabilization, a necessary tool for measurement of protein regulation. Journal of Proteomics 75:1, pages 145-159.
Crossref
Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio & Bruno Giardina. (2011) The proteomics of cancer stem cells. Potential clinical applications for innovative research in oncology. PROTEOMICS – Clinical Applications 5:11-12, pages 590-602.
Crossref
Carlotta Granchi, Sarabindu Roy, Alessio De Simone, Irene Salvetti, Tiziano Tuccinardi, Adriano Martinelli, Marco Macchia, Mario Lanza, Laura Betti, Gino Giannaccini, Antonio Lucacchini, Elisa Giovannetti, Rocco Sciarrillo, Godefridus J. Peters & Filippo Minutolo. (2011) N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation. European Journal of Medicinal Chemistry 46:11, pages 5398-5407.
Crossref
Emma E. Ramsay, Philip J. Hogg & Pierre J. Dilda. (2011) Mitochondrial Metabolism Inhibitors for Cancer Therapy. Pharmaceutical Research 28:11, pages 2731-2744.
Crossref
Craig D. Smith, Debasish Chattopadhyay & Biswajit Pal. (2011) Crystal structure of Plasmodium falciparum phosphoglycerate kinase: Evidence for anion binding in the basic patch. Biochemical and Biophysical Research Communications 412:2, pages 203-206.
Crossref
Woo Sik Yu, Soo-Jin Jeong, Ji-Hyun Kim, Hyo-Jung Lee, Hyo Sook Song, Min-Seok Kim, Eunjung Ko, Hyo-Jeong Lee, Jae-Ho Khil, Hyeung-Jin Jang, Young Chul Kim, Hyunsu Bae, Chang Yan Chen & Sung-Hoon Kim. (2011) The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: Molecular target on cancer metabolism. Molecules and Cells 32:2, pages 123-132.
Crossref
Yuhua Zhao, Hao Liu, Zixing Liu, Yan Ding, Susan P. LeDoux, Glenn L. Wilson, Richard Voellmy, Yifeng Lin, Wensheng Lin, Rita Nahta, Bolin Liu, Oystein Fodstad, Jieqing Chen, Yun Wu, Janet E. Price & Ming Tan. (2011) Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism. Cancer Research 71:13, pages 4585-4597.
Crossref
Dong Hoon Suh, Mi-Kyung Kim, Jae Hong No, Hyun Hoon Chung & Yong Sang Song. (2011) Metabolic approaches to overcoming chemoresistance in ovarian cancer. Annals of the New York Academy of Sciences 1229:1, pages 53-60.
Crossref
Hwee Ying Lim, Qin Shi Ho, Jeffrey Low, Mahesh Choolani & Kim Ping Wong. (2011) Respiratory competent mitochondria in human ovarian and peritoneal cancer. Mitochondrion 11:3, pages 437-443.
Crossref
Carlotta Granchi, Sarabindu Roy, Chiara Giacomelli, Marco Macchia, Tiziano Tuccinardi, Adriano Martinelli, Mario Lanza, Laura Betti, Gino Giannaccini, Antonio Lucacchini, Nicola Funel, Leticia G. León, Elisa Giovannetti, Godefridus J. Peters, Rahul Palchaudhuri, Emilia C. Calvaresi, Paul J. Hergenrother & Filippo Minutolo. (2011) Discovery of N -Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells . Journal of Medicinal Chemistry 54:6, pages 1599-1612.
Crossref
Wayne M Eby, Mohammad A Tabatabai & Zoran Bursac. (2010) Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide. BMC Cancer 10:1.
Crossref
Min Li, Lujun Song & Xinyu Qin. (2010) Glycan changes: cancer metastasis and anti-cancer vaccines. Journal of Biosciences 35:4, pages 665-673.
Crossref
D Sears, P Luong, M Yuan, G Nteliopoulos, Y K S Man, J V Melo & S Basu. (2010) Functional phosphoproteomic analysis reveals cold-shock domain protein A to be a Bcr-Abl effector-regulating proliferation and transformation in chronic myeloid leukemia. Cell Death & Disease 1:11, pages e93-e93.
Crossref
Soon Ok Cho, Joo Weon Lim, Jong-Ho Jun, Kyung Hwan Kim & Hyeyoung Kim. (2009) Helicobacter pylori in a Korean Isolate Expressed Proteins Differentially in Human Gastric Epithelial Cells. Digestive Diseases and Sciences 55:6, pages 1550-1564.
Crossref
Shih-Hsin Tu, Chih-Chiang Chang, Ching-Shyang Chen, Ka-Wai Tam, Ying-Jan Wang, Chia-Hwa Lee, Hsiao-Wei Lin, Tzu-Chun Cheng, Ching-Shui Huang, Jan-Show Chu, Neng-Yao Shih, Li-Ching Chen, Sy-Jye Leu, Yuan-Soon Ho & Chih-Hsiung Wu. (2009) Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells. Breast Cancer Research and Treatment 121:3, pages 539-553.
Crossref
Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio & Bruno Giardina. (2010) Revisiting the Warburg effect in cancer cells with proteomics. The emergence of new approaches to diagnosis, prognosis and therapy. PROTEOMICS – Clinical Applications 4:2, pages 143-158.
Crossref
Maria Wartenberg, Madeleine Richter, André Datchev, Sebastian Günther, Nada Milosevic, Mohamed M. Bekhite, Hans‐Reiner Figulla, Josep M. Aran, Jordi Pétriz & Heinrich Sauer. (2009) Glycolytic pyruvate regulates P‐Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state. Journal of Cellular Biochemistry 109:2, pages 434-446.
Crossref
Helene Rundqvist & Randall S. Johnson. 2010. Diverse Effects of Hypoxia on Tumor Progression. Diverse Effects of Hypoxia on Tumor Progression 121 139 .
A Colell, D R Green & J-E Ricci. (2009) Novel roles for GAPDH in cell death and carcinogenesis. Cell Death & Differentiation 16:12, pages 1573-1581.
Crossref
Mala Shanmugam, Samuel K McBrayer & Steven T Rosen. (2009) Targeting the Warburg effect in hematological malignancies: from PET to therapy. Current Opinion in Oncology 21:6, pages 531-536.
Crossref
Francesco AddabboMonica MontagnaniMichael S. Goligorsky. (2009) Mitochondria and Reactive Oxygen Species. Hypertension 53:6, pages 885-892.
Crossref
Vladimir Gogvadze, Sten Orrenius & Boris Zhivotovsky. (2009) Mitochondria as targets for cancer chemotherapy. Seminars in Cancer Biology 19:1, pages 57-66.
Crossref
David Ollitrault, Valentina Buffa, Rosamaria Correra, Angeliqua Sayed, Bénédicte Hoareau, Sophie Pöhle-Kronawitter, Sigmar Stricker, Jean-Sebastien Hulot, Mariana Valente, Giovanna Marazzi & David Sassoon. (2021) Fibroadipogenic Progenitors Contribute to Microvascular Repair During Skeletal Muscle Regeneration. SSRN Electronic Journal.
Crossref

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