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Drug Evaluation

Prolonged-release melatonin for the treatment of insomnia in patients over 55 years

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Pages 1567-1572 | Published online: 22 Sep 2008

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Lukas Frase, Christoph Nissen, Dieter Riemann & Kai Spiegelhalder. (2018) Making sleep easier: pharmacological interventions for insomnia. Expert Opinion on Pharmacotherapy 19:13, pages 1465-1473.
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Joanna Rybka, Kornelia Kędziora-Kornatowska, Daria Kupczyk, Marta Muszalik, Maciej Kornatowski & Józef Kędziora. (2016) Antioxidant effect of immediate- versus sustained-release melatonin in type 2 diabetes mellitus and healthy controls. Drug Delivery 23:3, pages 804-807.
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Alan G Wade, Mildred Farmer, Gil Harari, Naama Fund, Moshe Laudon, Tali Nir, Anat Frydman-Marom & Nava Zisapel. (2014) Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer’s disease: a 6-month, randomized, placebo-controlled, multicenter trial. Clinical Interventions in Aging 9, pages 947-961.
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Doron Garfinkel, Mariana Zorin, Julio Wainstein, Zipora Matas, Moshe Laudon & Nava Zisapel. (2011) Efficacy and safety of prolonged-release melatonin in insomnia patients with diabetes: a randomized, double-blind, crossover study. Diabetes, Metabolic Syndrome and Obesity 4, pages 307-313.
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D Alan Lankford. (2011) Tasimelteon for insomnia. Expert Opinion on Investigational Drugs 20:7, pages 987-993.
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Po-Yu Huang, Jheng-Yan Wu, Ting-Hui Liu, Ya-Wen Tsai, Po-Tsang Chen, Chia-Te Liao & Han Siong Toh. (2023) The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Medicine 10.
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Mingyu Yi, Sixue Wang, Ting WuXinyue Zhang, Li Jiang & Xiaoling Fang. (2021) Effects of exogenous melatonin on sleep quality and menopausal symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials. Menopause 28:6, pages 717-725.
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W. Cassel & P. Cassel. (2020) Guter Schlaf im besten AlterBien dormir dans la force de l’âge. Journal für Gynäkologische Endokrinologie/Schweiz 23:3, pages 86-93.
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Seog Ju Kim. (2020) Recent Advances in Diagnosis and Treatment of Insomnia Disorder. Journal of Korean Neuropsychiatric Association 59:1, pages 2.
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Jan Frölich, Alfred Wiater & Gerd Lehmkuhl. (2019) Melatonin in der Behandlung von Insomnien und Schlaf-Wach-Rhythmusstörungen im Kindes- und JugendalterMelatonin in the treatment of insomnia and sleep-wake rhythm disorders in children and adolescents. Somnologie 23:4, pages 261-270.
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W. Cassel & P. Cassel. (2018) Guter Schlaf im besten AlterSleep well in the prime of life. Gynäkologische Endokrinologie 17:1, pages 49-55.
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Mohammad Hosein Farzaei, Marziyeh Hajialyani & Rozita Naseri. 2019. Nonvitamin and Nonmineral Nutritional Supplements. Nonvitamin and Nonmineral Nutritional Supplements 99 105 .
Pawel P. Posadzki, Ram Bajpai, Bhone Myint Kyaw, Nicola J. Roberts, Amnon Brzezinski, George I. Christopoulos, Ushashree Divakar, Shweta Bajpai, Michael Soljak, Gerard Dunleavy, Krister Jarbrink, Ei Ei Khaing Nang, Chee Kiong Soh & Josip Car. (2018) Melatonin and health: an umbrella review of health outcomes and biological mechanisms of action. BMC Medicine 16:1.
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Vivien C. Abad & Christian Guilleminault. (2018) Insomnia in Elderly Patients: Recommendations for Pharmacological Management. Drugs & Aging 35:9, pages 791-817.
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Maryam Aghakouchakzadeh, Mandana Izadpanah, Farhad Soltani & Mehrnoush Dianatkhah. (2017) Are Melatonin and its Agonist the Natural Solution for Prevention of Delirium in Critically Ill Patients? A Review of Current Studies. Jundishapur Journal of Natural Pharmaceutical Products In Press:In Press.
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Andrew H. Ford, Leon Flicker, Jurgen Passage, Bradley Wibrow, Matthew Anstey, Mark Edwards & Osvaldo P. Almeida. (2016) The Healthy Heart-Mind trial: melatonin for prevention of delirium following cardiac surgery: study protocol for a randomized controlled trial. Trials 17:1.
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Angela Wright, Jacqueline Diebold, Jaskiran Otal, Carly Stoneman, Jonathan Wong, Christine Wallace & Mark Duffett. (2015) The Effect of Melatonin on Benzodiazepine Discontinuation and Sleep Quality in Adults Attempting to Discontinue Benzodiazepines: A Systematic Review and Meta-Analysis. Drugs & Aging 32:12, pages 1009-1018.
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Andrew H. Ford & Osvaldo P. Almeida. (2015) Pharmacological interventions for preventing delirium in the elderly. Maturitas 81:2, pages 287-292.
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Mahaveer Singh & Hemant R. Jadhav. (2014) Melatonin: functions and ligands. Drug Discovery Today 19:9, pages 1410-1418.
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Sifat Maria & Paula A. Witt-Enderby. (2014) Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures. Journal of Pineal Research 56:2, pages 115-125.
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Alexandra M. Wennberg, Sarah L. Canham, Michael T. Smith & Adam P. Spira. (2013) Optimizing sleep in older adults: Treating insomnia. Maturitas 76:3, pages 247-252.
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Mary P. Kotlarczyk, Holly C. Lassila, Christine K. O’Neil, Frank D’Amico, Larry T. Enderby, Paula A. Witt-Enderby & Judith L. Balk. (2012) Melatonin osteoporosis prevention study (MOPS): a randomized, double-blind, placebo-controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women. Journal of Pineal Research 52:4, pages 414-426.
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Jane NiklesVictor LoJennifer A GiamBandana Saini. (2012) Exploring melatonin prescribing among customers of compounding pharmacies in Australia. Medical Journal of Australia 196:6, pages 384-385.
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Nico J. Diederich & Deborah J. McIntyre. (2012) Sleep disorders in Parkinson's disease: Many causes, few therapeutic options. Journal of the Neurological Sciences 314:1-2, pages 12-19.
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Paula Witt-Enderby, William Clafshenkel, Mary Kotlarczyk & Shalini Sethi. 2011. Melatonin in the Promotion of Health, Second Edition. Melatonin in the Promotion of Health, Second Edition 261 270 .
Béatrice Guardiola-Lemaître & Maria Antonia Quera-Salva. 2011. Principles and Practice of Sleep Medicine. Principles and Practice of Sleep Medicine 420 430 .
S. Schwarz, L. Frölich & M. Deuschle. (2010) Schlafstörungen bei älteren MenschenInsomnia in the elderly: an under-diagnosed and over-treated syndrome. Der Internist 51:7, pages 914-922.
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Mónica Ambriz-Tututi, Héctor I. Rocha-González, Silvia L. Cruz & Vinicio Granados-Soto. (2009) Melatonin: A hormone that modulates pain. Life Sciences 84:15-16, pages 489-498.
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