Citations (38)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Pierre L Beaulieu. (2009) Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection. Expert Opinion on Therapeutic Patents 19:2, pages 145-164.
Read now
Read now
Arthur Y Kim & Joerg Timm. (2008) Resistance mechanisms in HCV: from evolution to intervention. Expert Review of Anti-infective Therapy 6:4, pages 463-478.
Read now
Read now
Articles from other publishers (36)
Ching-Hung Lin, Hon-Man-Herman Tam, Cheng-Yao Yang, Feng-Cheng Hsieh, Jiun-Long Wang, Chun-Chun Yang, Hsuan-Wei Hsu, Hao-Ping Liu & Hung-Yi Wu. (2023) Evolution of the coronavirus spike protein in the full-length genome and defective viral genome under diverse selection pressures. Journal of General Virology 104:11.
Crossref
Crossref
Ching-Hung Lin, Cheng-Yao Yang, Shan-Chia Ou, Meilin Wang, Chen-Yu Lo, Tsung-Lin Tsai & Hung-Yi Wu. (2020) The Impacts of Antivirals on the Coronavirus Genome Structure and Subsequent Pathogenicity, Virus Fitness and Antiviral Design. Biomedicines 8:10, pages 376.
Crossref
Crossref
Franck Amblard, Seema Mengshetti, Junxing Shi, Sijia Tao, Leda Bassit & Raymond F. Schinazi. 2020. The Liver. The Liver
906
914
.
Rolf Wagner, John T. Randolph, Sachin V. Patel, Lissa Nelson, Mark A. Matulenko, Ryan Keddy, John K. Pratt, Dachun Liu, A. Chris Krueger, Pamela L. Donner, Douglas K. Hutchinson, Charles Flentge, David Betebenner, Todd Rockway, Clarence J. Maring, Teresa I. Ng, Preethi Krishnan, Tami Pilot-Matias, Christine Collins, Neeta Panchal, Thomas Reisch, Tatyana Dekhtyar, Rubina Mondal, DeAnne F. Stolarik, Yi Gao, Wenqing Gao, David A. Beno & Warren M. Kati. (2018) Highlights of the Structure–Activity Relationships of Benzimidazole Linked Pyrrolidines Leading to the Discovery of the Hepatitis C Virus NS5A Inhibitor Pibrentasvir (ABT-530). Journal of Medicinal Chemistry 61:9, pages 4052-4066.
Crossref
Crossref
Pablo Hernández-Alonso, Raquel Garijo, José M. Cuevas & Rafael Sanjuán. (2015) Experimental evolution of an RNA virus in cells with innate immunity defects. Virus Evolution 1:1, pages vev008.
Crossref
Crossref
John A. McCauley, Michael T. Rudd & Nigel J. Liverton. 2013. Successful Strategies for the Discovery of Antiviral Drugs. Successful Strategies for the Discovery of Antiviral Drugs
189
247
.
Devendra K. Rai, Elizabeth A. Schafer, Kamalendra Singh, Mark A. McIntosh, Stefan G. Sarafianos & Elizabeth Rieder. (2013) Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells. Antiviral Research 98:3, pages 380-385.
Crossref
Crossref
Shailendra Asthana, Saumya Shukla, Attilio V. Vargiu, Matteo Ceccarelli, Paolo Ruggerone, Giuseppe Paglietti, Maria E. Marongiu, Sylvain Blois, Gabriele Giliberti & Paolo La Colla. (2013) Different Molecular Mechanisms of Inhibition of Bovine Viral Diarrhea Virus and Hepatitis C Virus RNA-Dependent RNA Polymerases by a Novel Benzimidazole. Biochemistry 52:21, pages 3752-3764.
Crossref
Crossref
Nicholas A. Meanwell, Stanley V. D'Andrea, Christopher W. Cianci, Ira B. Dicker, Kap‐Sun Yeung, Makonen Belema & Mark Krystal. 2013. Drug Discovery. Drug Discovery
439
515
.
G. Li, K. Li, A. S. Lea, N. L. Li, N. E. Abdulla, M. A. Eltorky & M. R. Ferguson. (2012)
In situ
hybridization for the detection of hepatitis C virus
RNA
in human liver tissue
. Journal of Viral Hepatitis 20:3, pages 183-192.
Crossref
Crossref
Benoit Devogelaere, Jan Martin Berke, Leen Vijgen, Pascale Dehertogh, Els Fransen, Erna Cleiren, Liesbet van der Helm, Origène Nyanguile, Abdellah Tahri, Katie Amssoms, Oliver Lenz, Maxwell D. Cummings, Reginald F. Clayton, Sandrine Vendeville, Pierre Raboisson, Kenneth A. Simmen, Gregory C. Fanning & Tse-I Lin. (2012) TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage. Antimicrobial Agents and Chemotherapy 56:9, pages 4676-4684.
Crossref
Crossref
Pierre Raboisson, Gregory Fanning, Herman de Kock, Åsa Rosenquist, René Verloes & Kenneth Simmen. 2011. Antiviral Drugs. Antiviral Drugs
273
286
.
Jan Martin Berke, Leen Vijgen, Sophie Lachau-Durand, Megan H. Powdrill, Svea Rawe, Elena Sjuvarsson, Staffan Eriksson, Matthias Götte, Els Fransen, Pascale Dehertogh, Christel Van den Eynde, Laurent Leclercq, Tim H. M. Jonckers, Pierre Raboisson, Magnus Nilsson, Bertil Samuelsson, Åsa Rosenquist, Gregory C. Fanning & Tse-I Lin. (2011) Antiviral Activity and Mode of Action of TMC647078, a Novel Nucleoside Inhibitor of the Hepatitis C Virus NS5B Polymerase. Antimicrobial Agents and Chemotherapy 55:8, pages 3812-3820.
Crossref
Crossref
V. Soriano, E. Vispo, E. Poveda, P. Labarga, L. Martin-Carbonero, J. V. Fernandez-Montero & P. Barreiro. (2011) Directly acting antivirals against hepatitis C virus. Journal of Antimicrobial Chemotherapy 66:8, pages 1673-1686.
Crossref
Crossref
Robert G. Gish & Nicholas A. Meanwell. (2011) The NS5A Replication Complex Inhibitors: Difference Makers?. Clinics in Liver Disease 15:3, pages 627-639.
Crossref
Crossref
Margaret Robinson, Yang Tian, William E. DelaneyIVIV & Andrew E. Greenstein. (2011) Preexisting drug-resistance mutations reveal unique barriers to resistance for distinct antivirals. Proceedings of the National Academy of Sciences 108:25, pages 10290-10295.
Crossref
Crossref
Guofeng Cheng, Katie Chan, Huiling Yang, Amy Corsa, Maria Pokrovskii, Matthew Paulson, Gina Bahador, Weidong Zhong & William DelaneyIVIV. (2011) Selection of Clinically Relevant Protease Inhibitor-Resistant Viruses Using the Genotype 2a Hepatitis C Virus Infection System. Antimicrobial Agents and Chemotherapy 55:5, pages 2197-2205.
Crossref
Crossref
Ran Yan, Zhenhuan Zhao, Yawen He, Lin Wu, Dawei Cai, Wei Hong, Yingliang Wu, Zhijian Cao, Congyi Zheng & Wenxin Li. (2011) A new natural α-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV. Peptides 32:1, pages 11-19.
Crossref
Crossref
Matthew S. Paulson. (2010) Generation and Quantitation of Infectious Hepatitis C Virus Derived from Cell Culture (HCVcc). Current Protocols in Pharmacology 51:1.
Crossref
Crossref
Thierry Verbinnen, Herwig Van Marck, Ina Vandenbroucke, Leen Vijgen, Marijke Claes, Tse-I Lin, Kenneth Simmen, Johan Neyts, Gregory Fanning & Oliver Lenz. (2010)
Tracking the Evolution of Multiple
In Vitro
Hepatitis C Virus Replicon Variants under Protease Inhibitor Selection Pressure by 454 Deep Sequencing
. Journal of Virology 84:21, pages 11124-11133.
Crossref
Crossref
Tianmin Zhu, Mahdi B. Fawzi, Michael Flint, Fangming Kong, Jan Szeliga, Russ Tsao, Anita Y.M. Howe & Weitao Pan. (2010) Design and synthesis of HCV agents with sequential triple inhibitory potentials. Bioorganic & Medicinal Chemistry Letters 20:17, pages 5212-5216.
Crossref
Crossref
Shadi Salloum, Silvia F. Kluge, Arthur Y. Kim, Michael Roggendorf & Joerg Timm. (2010) The resistance mutation R155K in the NS3/4A protease of hepatitis C virus also leads the virus to escape from HLA-A*68-restricted CD8 T cells. Antiviral Research 87:2, pages 272-275.
Crossref
Crossref
Kevin D. Raney, Suresh D. Sharma, Ibrahim M. Moustafa & Craig E. Cameron. (2010) Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target. Journal of Biological Chemistry 285:30, pages 22725-22731.
Crossref
Crossref
Oliver Lenz, Thierry Verbinnen, Tse-I Lin, Leen Vijgen, Maxwell D. Cummings, Jimmy Lindberg, Jan Martin Berke, Pascale Dehertogh, Els Fransen, Annick Scholliers, Katrien Vermeiren, Tania Ivens, Pierre Raboisson, Michael Edlund, Susan Storm, Lotta Vrang, Herman de Kock, Gregory C. Fanning & Kenneth A. Simmen. (2010)
In Vitro
Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435
. Antimicrobial Agents and Chemotherapy 54:5, pages 1878-1887.
Crossref
Crossref
D. Andrew Knight, Thomas E. Hickey, Jason E. Bongard, Dzung C. Thach, R. Yngard & Eddie L. Chang. (2010) Differential effects of Co(III), Ni(II), and Ru(III) amine complexes on Sindbis virus. Journal of Inorganic Biochemistry 104:5, pages 592-598.
Crossref
Crossref
Maxwell D. Cummings, Jimmy Lindberg, Tse‐I Lin, Herman de Kock, Oliver Lenz, Elisabet Lilja, Sara Felländer, Vera Baraznenok, Susanne Nyström, Magnus Nilsson, Lotta Vrang, Michael Edlund, Åsa Rosenquist, Bertil Samuelsson, Pierre Raboisson & Kenneth Simmen. (2010) Induced‐Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target. Angewandte Chemie International Edition 49:9, pages 1652-1655.
Crossref
Crossref
Maxwell D. Cummings, Jimmy Lindberg, Tse‐I Lin, Herman de Kock, Oliver Lenz, Elisabet Lilja, Sara Felländer, Vera Baraznenok, Susanne Nyström, Magnus Nilsson, Lotta Vrang, Michael Edlund, Åsa Rosenquist, Bertil Samuelsson, Pierre Raboisson & Kenneth Simmen. (2010) Induced‐Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target. Angewandte Chemie 122:9, pages 1696-1699.
Crossref
Crossref
R. F. Schinazi, L. Bassit & C. Gavegnano. (2010) HCV drug discovery aimed at viral eradication. Journal of Viral Hepatitis 17:2, pages 77-90.
Crossref
Crossref
Jean‐Pierre Gillet, Michael M. Gottesman & Mitsunori Okabe. 2009. The Liver. The Liver
1075
1090
.
J. J. WEISS, N. BRÄU, A. STIVALA, T. SWAN & D. FISHBEIN. (2009) Review article: adherence to medication for chronic hepatitis C - building on the model of human immunodeficiency virus antiretroviral adherence research. Alimentary Pharmacology & Therapeutics 30:1, pages 14-27.
Crossref
Crossref
HELGE MYRMEL, ELLING ULVESTAD & BIRGITTA ÅSJØ. (2009) The hepatitis C virus enigma. APMIS 117:5-6, pages 427-439.
Crossref
Crossref
Jinhong Chang, Lijuan Wang, Dongling Ma, Xiaowang Qu, Haitao Guo, Xiaodong Xu, Peter M. Mason, Nigel Bourne, Robert Moriarty, Baohua Gu, Ju-Tao Guo & Timothy M. Block. (2009) Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses. Antimicrobial Agents and Chemotherapy 53:4, pages 1501-1508.
Crossref
Crossref
Vincent Soriano, Marion G. Peters & Stefan Zeuzem. (2009) New Therapies for Hepatitis C Virus Infection. Clinical Infectious Diseases 48:3, pages 313-320.
Crossref
Crossref
Nicholas A. Meanwell, John F. Kadow & Paul M. Scola. 2009. Annual Reports in Medicinal Chemistry Volume 44. Annual Reports in Medicinal Chemistry Volume 44
397
440
.
Joanna E. Mathy, Sue Ma, Teresa Compton & Kai Lin. (2008) Combinations of Cyclophilin Inhibitor NIM811 with Hepatitis C Virus NS3-4A Protease or NS5B Polymerase Inhibitors Enhance Antiviral Activity and Suppress the Emergence of Resistance. Antimicrobial Agents and Chemotherapy 52:9, pages 3267-3275.
Crossref
Crossref
Mark Mascolini, Douglas Richman, Brendan Larder, John Mellors & Charles AB Boucher. (2008) Clinical Implications of Resistance to Antiretrovirals: New Resistance Technologies and Interpretations. Antiviral Therapy 13:2, pages 319-334.
Crossref
Crossref