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Drug Evaluations

Brivaracetam: a new drug in development for epilepsy and neuropathic pain

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Pages 361-369 | Published online: 06 Mar 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Jéssica Domingos da Silva, Lucio Mendes Cabral & Valéria Pereira de Sousa. (2022) Stability Indicating Methods for Determination of Third Generation Antiepileptic Drugs and Their Related Substances. Critical Reviews in Analytical Chemistry 52:7, pages 1524-1536.
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Joseph V. Pergolizzi$suffix/text()$suffix/text(), Christopher Gharibo, Peter Magnusson, Frank Breve, Jo Ann LeQuang & Giustino Varrassi. (2022) Pharmacotherapeutic management of trigeminal neuropathic pain: an update. Expert Opinion on Pharmacotherapy 23:10, pages 1155-1164.
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Laurent Maximilian Willems, Sebastian Bauer, Felix Rosenow & Adam Strzelczyk. (2019) Recent advances in the pharmacotherapy of epilepsy: brivaracetam and perampanel as broad-spectrum antiseizure drugs for the treatment of epilepsies and status epilepticus. Expert Opinion on Pharmacotherapy 20:14, pages 1755-1765.
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Jasmina R. Milovanović, Slobodan M. Janković, Ana Pejčić, Miloš Milosavljević, Valentina Opančina, Vesela Radonjić, Zoran Protrka & Marina Kostić. (2017) Evaluation of brivaracetam: a new drug to treat epilepsy. Expert Opinion on Pharmacotherapy 18:13, pages 1381-1389.
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Adam Strzelczyk, Karl Martin Klein, Laurent M. Willems, Felix Rosenow & Sebastian Bauer. (2016) Brivaracetam in the treatment of focal and idiopathic generalized epilepsies and of status epilepticus. Expert Review of Clinical Pharmacology 9:5, pages 637-645.
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Xin Tian, Meizhen Yuan, Qingju Zhou & Xuefeng Wang. (2015) The efficacy and safety of brivaracetam at different doses for partial-onset epilepsy: a meta-analysis of placebo-controlled studies. Expert Opinion on Pharmacotherapy 16:12, pages 1755-1767.
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Andreas Schulze-Bonhage. (2011) Brivaracetam for the treatment of epilepsy. Expert Opinion on Pharmacotherapy 12:12, pages 1959-1966.
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Articles from other publishers (18)

Peng-Peng Wu, Bi-Rong Cao, Fu-Yun Tian & Zhao-Bing Gao. (2023) Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil. Neuroscience Bulletin.
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Laura Palumbo, Marianna Carinci, Annunziata Guarino, Laila Asth, Silvia Zucchini, Sonia Missiroli, Alessandro Rimessi, Paolo Pinton & Carlotta Giorgi. (2023) The NLRP3 Inflammasome in Neurodegenerative Disorders: Insights from Epileptic Models. Biomedicines 11:10, pages 2825.
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Guo-Li Shen, Yuan-Yuan Tan, Yuan Hu, Zhi-Chao Chen, Wei Du & Ying-Chun Chen. (2023) Asymmetric Construction of Multifunctional γ-Lactams from 1,3-Dienes and α-Ketoamides via Pd(0)-π-Lewis Base Catalysis. Organic Letters 25:36, pages 6649-6653.
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Cheng-Shih Chen, Edmund Cheung So & Sheng-Nan Wu. (2023) Modulating Hyperpolarization-Activated Cation Currents through Small Molecule Perturbations: Magnitude and Gating Control. Biomedicines 11:8, pages 2177.
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Kiran Kumar Aalapati, Amit Singh & Ranjana S.Patnaik. (2022) A Brief Review of Analytical Methods for the Estimation of Brivaracetam in Pharmaceutical Formulation and Biological Matrices. Journal of Advanced Zoology 43:1, pages 89-95.
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Katharina Kneppe & David Czell. (2022) Brivaracetam – eine gute Alternative in der akuten Behandlung der Trigeminusneuralgie. Praxis 111:1, pages 21-25.
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Dafin F. Muresanu, Olivia Verisezan Rosu, Codruta Birle, Livia Popa, Diana Chira, Stefan Strilciuc & Anca Dana Buzoianu. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 4095 4126 .
Babji Palakeeti, K. Vijendar Reddy, K. Vengatajalabathy Gobi, Pothuraju Nageswara Rao & Jugun Prakash Chinta. (2021) Simple and efficient method for the quantification of antiepileptic drugs in human plasma by using magnetic graphene oxide-β-cyclodextrin composite as a sorbent. Future Journal of Pharmaceutical Sciences 7:1.
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Te-Yu Hung, Sheng-Nan Wu & Chin-Wei Huang. (2021) The Integrated Effects of Brivaracetam, a Selective Analog of Levetiracetam, on Ionic Currents and Neuronal Excitability. Biomedicines 9:4, pages 369.
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Dafin F. Muresanu, Olivia Verisezan Rosu, Codruta Birle, Livia Popa, Diana Chira, Stefan Strilciuc & Anca Dana Buzoianu. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 32 .
A. Strzelczyk, I. Steinig, K. M. Klein, L. M. Willems, S. Knake, F. Rosenow & S. Bauer. (2016) Brivaracetam zur Zusatztherapie bei fokalen EpilepsienBrivaracetam for add-on treatment in focal epilepsy. Der Nervenarzt 87:10, pages 1086-1093.
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Isabelle Niespodziany, Véronique Marie André, Nathalie Leclère, Etienne Hanon, Philippe Ghisdal & Christian Wolff. (2014) Brivaracetam Differentially Affects Voltage‐Gated Sodium Currents Without Impairing Sustained Repetitive Firing in Neurons. CNS Neuroscience & Therapeutics 21:3, pages 241-251.
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Detlev Boison. (2013) Adenosine Kinase: Exploitation for Therapeutic Gain. Pharmacological Reviews 65:3, pages 906-943.
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Pooja S. Banerjee & P. K. Sharma. (2011) New antiepileptic agents: structure–activity relationships. Medicinal Chemistry Research 21:7, pages 1491-1508.
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Michel Gillard, Bruno Fuks, Karine Leclercq & Alain Matagne. (2011) Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: Relationship to anti-convulsant properties. European Journal of Pharmacology 664:1-3, pages 36-44.
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Xiao-ling DUAN & Nong XIAO. (2011) From levetiracetam to brivaracetam: development of antiepileptic drugs. Academic Journal of Second Military Medical University 31:5, pages 550-553.
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Andrei G. Malykh & M. Reza Sadaie. (2010) Piracetam and Piracetam-Like Drugs. Drugs 70:3, pages 287-312.
Crossref
C P PanayiotopoulosC P Panayiotopoulos. 2010. A Clinical Guide to Epileptic Syndromes and their Treatment. A Clinical Guide to Epileptic Syndromes and their Treatment 533 563 .

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