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Drug Evaluations

Brentuximab vedotin: delivering an antimitotic drug to activated lymphoma cells

, MD PhD
Pages 99-105 | Published online: 02 Dec 2010

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John R Adair, Philip W Howard, John A Hartley, David G Williams & Kerry A Chester. (2012) Antibody–drug conjugates – a perfect synergy. Expert Opinion on Biological Therapy 12:9, pages 1191-1206.
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Hoda E. Mohamed, Medhat A. Al-Ghobashy, Samah S. Abbas & Shereen A. Boltia. (2023) Stability assessment of Polatuzumab vedotin and Brentuximab vedotin using different analytical techniques. Journal of Pharmaceutical and Biomedical Analysis 228, pages 115249.
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David Newman & Gordon Cragg. (2014) Marine-Sourced Anti-Cancer and Cancer Pain Control Agents in Clinical and Late Preclinical Development. Marine Drugs 12:1, pages 255-278.
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Antonio Gualberto. 2015. Molecular Oncology. Molecular Oncology 854 860 .
Mai Yoshikawa, Yohei Mukai, Yoshiaki Okada, Yuki Tsumori, Shin-ichi Tsunoda, Yasuo Tsutsumi, William C. Aird, Yasuo Yoshioka, Naoki Okada, Takefumi Doi & Shinsaku Nakagawa. (2013) Robo4 is an effective tumor endothelial marker for antibody-drug conjugates based on the rapid isolation of the anti-Robo4 cell-internalizing antibody. Blood 121:14, pages 2804-2813.
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Jonathan R. Fromm, Julie A. McEarchern, Dana Kennedy, Anju Thomas, Andrei R. Shustov & Ajay K. Gopal. (2012) Clinical Binding Properties, Internalization Kinetics, and Clinicopathologic Activity of Brentuximab Vedotin: An Antibody-Drug Conjugate for CD30-Positive Lymphoid Neoplasms. Clinical Lymphoma Myeloma and Leukemia 12:4, pages 280-283.
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Bettina Bisig, Philippe Gaulard & Laurence de Leval. (2012) New biomarkers in T-cell lymphomas. Best Practice & Research Clinical Haematology 25:1, pages 13-28.
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Deron R. Herr. 2012. International Review of Cell and Molecular Biology Volume 297. International Review of Cell and Molecular Biology Volume 297 45 81 .
Gregory Landes & Kathleen Elias. 2012. Development of Antibody-Based Therapeutics. Development of Antibody-Based Therapeutics 183 240 .
Bérengère Vire, Alexandre David & Adrian Wiestner. (2011) TOSO, the Fcμ Receptor, Is Highly Expressed on Chronic Lymphocytic Leukemia B Cells, Internalizes upon IgM Binding, Shuttles to the Lysosome, and Is Downregulated in Response to TLR Activation. The Journal of Immunology 187:8, pages 4040-4050.
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