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Drug Evaluations

Patupilone in cancer treatment

, MD & , MD FRCP
Pages 107-117 | Published online: 11 Dec 2010

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Erika Vacchelli, Fernando Aranda, Alexander Eggermont, Jérôme Galon, Catherine Sautès-Fridman, Isabelle Cremer, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2014) Trial Watch. OncoImmunology 3:3.
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Erika Vacchelli, Laura Senovilla, Alexander Eggermont, Wolf Hervé Fridman, Jérôme Galon, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi. (2013) Trial watch. OncoImmunology 2:3.
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Diana P English, Dana M Roque & Alessandro D Santin. (2013) Class III b-tubulin overexpression in gynecologic tumors: implications for the choice of microtubule targeted agents?. Expert Review of Anticancer Therapy 13:1, pages 63-74.
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Articles from other publishers (20)

Mitesh Patel, Julia Riede, Dallas Bednarczyk, Birk Poller & Sujal V. Deshmukh. (2023) Simplifying the Extended Clearance Concept Classification System (EC3S) to Guide Clearance Prediction in Drug Discovery. Pharmaceutical Research 40:4, pages 937-949.
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Cecilia Villegas, Iván González-Chavarría, Viviana Burgos, Héctor Iturra-Beiza, Henning Ulrich & Cristian Paz. (2023) Epothilones as Natural Compounds for Novel Anticancer Drugs Development. International Journal of Molecular Sciences 24:7, pages 6063.
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Aneta Rogalska & Agnieszka Marczak. (2018) Therapeutic potential of patupilone in epithelial ovarian cancer and future directions. Life Sciences 205, pages 38-44.
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Dae Hwan Shin & Glen S. Kwon. (2017) Epothilone B-based 3-in-1 polymeric micelle for anticancer drug therapy. International Journal of Pharmaceutics 518:1-2, pages 307-311.
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Raphael Schiess & Karl-Heinz Altmann. 2014. Macrocycles in Drug Discovery. Macrocycles in Drug Discovery 78 108 .
D. M. Peereboom, C. Murphy, M. S. Ahluwalia, A. Conlin, A. Eichler, C. Van Poznak, J. Baar, P. Elson & A. D. Seidman. (2014) Phase II trial of patupilone in patients with brain metastases from breast cancer. Neuro-Oncology 16:4, pages 579-583.
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Karl-Heinz Altmann & Dieter Schinzer. 2014. Natural Products in Medicinal Chemistry. Natural Products in Medicinal Chemistry 81 126 .
Jonathan D Black, Diana P English, Dana M Roque & Alessandro D Santin. (2014) Targeted Therapy in Uterine Serous Carcinoma: An Aggressive Variant of Endometrial Cancer. Women's Health 10:1, pages 45-57.
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S. Y. Moorcraft, I. Chau, C. Peckitt, D. Cunningham, S. Rao, K. L. Yim, A. Walther, C. G. C. A. Jackson, G. Stamp, J. Webb, G. Smith, A. Gillbanks & C. Swanton. (2013) Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial. Investigational New Drugs 31:5, pages 1339-1344.
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Aneta Rogalska, Ewa Szula, Arkadiusz Gajek, Agnieszka Marczak & Zofia Jóźwiak. (2013) Activation of apoptotic pathway in normal, cancer ovarian cells by epothilone B. Environmental Toxicology and Pharmacology 36:2, pages 600-610.
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Dana M. Roque, Stefania Bellone, Natalia Buza, Chiara Romani, Emiliano Cocco, Eliana Bignotti, Antonella Ravaggi, Thomas J. Rutherford, Peter E. Schwartz, Sergio Pecorelli & Alessandro D. Santin. (2013) Class III β-tubulin overexpression in ovarian clear cell and serous carcinoma as a maker for poor overall survival after platinum/taxane chemotherapy and sensitivity to patupilone. American Journal of Obstetrics and Gynecology 209:1, pages 62.e1-62.e9.
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V. Meier, C. Geigy, N. Grosse, P. McSheehy & C. Rohrer Bley. (2012) Use of Epothilone B (Patupilone) in Refractory Lymphoma and Advanced Solid Tumors in Dogs. Journal of Veterinary Internal Medicine 27:1, pages 120-125.
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Bernhard Pfeiffer, Fabienne Zdenka Gaugaz, Raphael Schiess & Karl-Heinz Altmann*. 2012. Drug Discovery from Natural Products. Drug Discovery from Natural Products 339 373 .
Daniel P. Fitzgerald, David L. Emerson, Yongzhen Qian, Talha Anwar, David J. Liewehr, Seth M. Steinberg, Sandra Silberman, Diane Palmieri & Patricia S. Steeg. (2012) TPI-287, a New Taxane Family Member, Reduces the Brain Metastatic Colonization of Breast Cancer Cells. Molecular Cancer Therapeutics 11:9, pages 1959-1967.
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Ruth A. Entwistle, Rania S. Rizk, Daniel M. Cheng, Gerald H. Lushington, Richard H. Himes & Mohan L. GuptaJr.Jr.. (2012) Differentiating between Models of Epothilone Binding to Microtubules Using Tubulin Mutagenesis, Cytotoxicity, and Molecular Modeling. ChemMedChem 7:9, pages 1580-1586.
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Alessandra Pagano, Stéphane Honoré, Renu Mohan, Raphael Berges, Anna Akhmanova & Diane Braguer. (2012) Epothilone B inhibits migration of glioblastoma cells by inducing microtubule catastrophes and affecting EB1 accumulation at microtubule plus ends. Biochemical Pharmacology 84:4, pages 432-443.
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Christian Bailly. (2012) Contemporary Challenges in the Design of Topoisomerase II Inhibitors for Cancer Chemotherapy. Chemical Reviews 112:7, pages 3611-3640.
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Christopher J. Twelves & Monica N. Fornier. (2012) Choosing chemotherapy for patients with metastatic breast cancer previously exposed to taxanes and anthracyclines: other agents. Community Oncology 9:5, pages S13-S19.
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T. Baumgart, G. Klautke, S. Kriesen, S.A. Kuznetsov, D.G. Weiss, R. Fietkau, G. Hildebrandt & K. Manda. (2012) Radiosensitizing effect of epothilone B on human epithelial cancer cellsStrahlensensibilisierender Effekt von Epothilon B auf humane epitheliale Tumorzellen. Strahlentherapie und Onkologie 188:2, pages 177-184.
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E S Antonarakis & A J Armstrong. (2011) Evolving standards in the treatment of docetaxel-refractory castration-resistant prostate cancer. Prostate Cancer and Prostatic Diseases 14:3, pages 192-205.
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