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Investigational NMDA receptor modulators for depression

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Pages 91-102 | Published online: 21 Nov 2011

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Christopher L. Cioffi. (2018) Glycine transporter-1 inhibitors: a patent review (2011–2016). Expert Opinion on Therapeutic Patents 28:3, pages 197-210.
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Bartłomiej Pochwat, Agnieszka Pałucha-Poniewiera, Bernadeta Szewczyk, Andrzej Pilc & Gabriel Nowak. (2014) NMDA antagonists under investigation for the treatment of major depressive disorder. Expert Opinion on Investigational Drugs 23:9, pages 1181-1192.
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Marco A Grados, Matt W Specht, Hyung-Mo Sung & Diandra Fortune. (2013) Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach. Expert Opinion on Drug Discovery 8:12, pages 1515-1527.
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Joanna M Wierońska & Andrzej Pilc. (2013) Glutamate-based anxiolytic ligands in clinical trials. Expert Opinion on Investigational Drugs 22:8, pages 1007-1022.
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Chun Yang, Wei Zhou, Xiaomin Li, Jianjun Yang, Bernadeta Szewczyk, Agnieszka Pałucha-Poniewiera, Ewa Poleszak, Andrzej Pilc & Gabriel Nowak. (2012) A bright future of researching AMPA receptor agonists for depression treatment. Expert Opinion on Investigational Drugs 21:5, pages 583-585.
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Mehran Shayganfard. (2021) Are Essential Trace Elements Effective in Modulation of Mental Disorders? Update and Perspectives. Biological Trace Element Research 200:3, pages 1032-1059.
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Sheikh Salim, Sonone Pankaj, Verma Veena, Tripathi Chakra Dhar, Karim Bushra Ahmed & Meshram Girish Gulab. (2021) Comparative evaluation of anti-depressant effects of Citalopram, Ketamine and their combination in animal models of depression: A potential anti-depressant?. Open Journal of Pharmacology and Pharmacotherapeutics, pages 004-008.
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Meysam Amidfar, Marie Woelfer, Gislaine Z. Réus, João Quevedo, Martin Walter & Yong-Ku Kim. (2019) The role of NMDA receptor in neurobiology and treatment of major depressive disorder: Evidence from translational research. Progress in Neuro-Psychopharmacology and Biological Psychiatry 94, pages 109668.
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Ivana Perić, Andrijana Stanisavljević, Dragos Inta, Peter Gass, Undine E. Lang, Stefan Borgwardt & Dragana Filipović. (2019) Tianeptine antagonizes the reduction of PV+ and GAD67 cells number in dorsal hippocampus of socially isolated rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry 89, pages 386-399.
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Gislaine Zilli Réus, Airam Barbosa de Moura, Laura Araújo Borba, Helena Mendes Abelaira & João Quevedo. (2019) Strategies for Treatment-Resistant Depression: Lessons Learned from Animal Models. Complex Psychiatry 5:4, pages 178-189.
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Jessica Wang, Phoebe Um, Barbra Dickerman & Jianghong Liu. (2018) Zinc, Magnesium, Selenium and Depression: A Review of the Evidence, Potential Mechanisms and Implications. Nutrients 10:5, pages 584.
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Katarzyna Stachowicz. (2018) The role of DSCAM in the regulation of synaptic plasticity: possible involvement in neuropsychiatric disorders. Acta Neurobiologiae Experimentalis 78:3, pages 210-219.
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Meysam Amidfar, Gislaine Z. R?us, Jo?o Quevedo, Yong-Ku Kim & Mohammad Arbabi. (2017) Effect of co-administration of memantine and sertraline on the antidepressant-like activity and brain-derived neurotrophic factor (BDNF) levels in the rat brain. Brain Research Bulletin 128, pages 29-33.
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Francis L. Pazini, Mauricio P. Cunha, Julia M. Rosa, André R. S. Colla, Vicente Lieberknecht, Ágatha Oliveira & Ana Lúcia S. Rodrigues. (2015) Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway. Molecular Neurobiology 53:10, pages 6818-6834.
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Luís Félix, Luís Antunes, Sónia Campos, Carlos Venâncio & Ana Maria Coimbra. 2016. Neuropathology of Drug Addictions and Substance Misuse. Neuropathology of Drug Addictions and Substance Misuse 672 680 .
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Karolina Podkowa, Szymon Rzeźniczek, Marcin Marciniak, Francine Acher, Andrzej Pilc & Agnieszka Pałucha-Poniewiera. (2015) A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action. Neuropharmacology 97, pages 338-345.
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Bartlomiej Pochwat, Magdalena Sowa-Kucma, Katarzyna Kotarska, Paulina Misztak, Gabriel Nowak & Bernadeta Szewczyk. (2014) Antidepressant-like activity of magnesium in the olfactory bulbectomy model is associated with the AMPA/BDNF pathway. Psychopharmacology 232:2, pages 355-367.
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Helena Domin, Bernadeta Szewczyk, Monika Woźniak, Anika Wawrzak-Wleciał & Maria Śmiałowska. (2014) Antidepressant-like effect of the mGluR5 antagonist MTEP in an astroglial degeneration model of depression. Behavioural Brain Research 273, pages 23-33.
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Bartłomiej Pochwat, Bernadeta Szewczyk, Magdalena Sowa-Kucma, Agata Siwek, Urszula Doboszewska, Wojciech Piekoszewski, Piotr Gruca, Mariusz Papp & Gabriel Nowak. (2013) Antidepressant-like activity of magnesium in the chronic mild stress model in rats: alterations in the NMDA receptor subunits. The International Journal of Neuropsychopharmacology 17:03, pages 393-405.
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Hongli Sun, Lixia Guan, Zhongliang Zhu & Hui Li. (2013) Reduced Levels of NR1 and NR2A with Depression-Like Behavior in Different Brain Regions in Prenatally Stressed Juvenile Offspring. PLoS ONE 8:11, pages e81775.
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Julia D. I. Meuwese, Anouk M. van Loon, H. Steven Scholte, Philipp B. Lirk, Nienke C. C. Vulink, Markus W. Hollmann & Victor A. F. Lamme. (2013) NMDA Receptor Antagonist Ketamine Impairs Feature Integration in Visual Perception. PLoS ONE 8:11, pages e79326.
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Andrzej Pilc, Joanna M. Wierońska & Phil Skolnick. (2013) Glutamate-Based Antidepressants: Preclinical Psychopharmacology. Biological Psychiatry 73:12, pages 1125-1132.
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Katarzyna M?yniec, Bogus?awa Budziszewska, Witold Reczy?ski, Urszula Doboszewska, Andrzej Pilc & Gabriel Nowak. (2013) Zinc deficiency alters responsiveness to antidepressant drugs in mice. Pharmacological Reports 65:3, pages 579-592.
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Daniel C. Mathews, Ioline D. Henter & Carlos A. ZarateJrJr. (2012) Targeting the Glutamatergic System to Treat Major Depressive Disorder. Drugs 72:10, pages 1313-1333.
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