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Drug Evaluations

EC145: a novel targeted agent for adenocarcinoma of the lung

, MD & , MD
Pages 755-761 | Published online: 30 Mar 2012

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Lesheng Teng, Jing Xie, Lirong Teng & Robert J Lee. (2012) Clinical translation of folate receptor-targeted therapeutics. Expert Opinion on Drug Delivery 9:8, pages 901-908.
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O. Gherbovet, Pedro A. Sánchez-Murcia, M. C. García Alvarez, J. Bignon, S. Thoret, F. Gago & F. Roussi. (2015) Synthesis and evaluation of hybrid molecules targeting the vinca domain of tubulin. Organic & Biomolecular Chemistry 13:10, pages 3144-3154.
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Whitney S Graybill & Robert L Coleman. (2014) Vintafolide: a novel targeted agent for epithelial ovarian cancer. Future Oncology 10:4, pages 541-548.
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Christian Bailly. (2013) Cell-targeted cytotoxics: a new generation of cytotoxic agents for cancer treatment. Phytochemistry Reviews 13:1, pages 171-181.
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Mark S. Butler, Avril A. B. Robertson & Matthew A. Cooper. (2014) Natural product and natural product derived drugs in clinical trials. Nat. Prod. Rep. 31:11, pages 1612-1661.
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Josefine Reber, Stephanie Haller, Christopher P. Leamon & Cristina Müller. (2013) 177Lu-EC0800 Combined with the Antifolate Pemetrexed: Preclinical Pilot Study of Folate Receptor Targeted Radionuclide Tumor Therapy. Molecular Cancer Therapeutics 12:11, pages 2436-2445.
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Stefano Della-Longa & Alessandro Arcovito. (2013) Structural and functional insights on folate receptor α (FRα) by homology modeling, ligand docking and molecular dynamics. Journal of Molecular Graphics and Modelling 44, pages 197-207.
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