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Expert Opinion on Investigational Drugs Volume 21, 2012 - Issue 7
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Editorial

The elvitegravir Quad pill: the first once-daily dual-target anti-HIV tablet

Christophe MarchandNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Laboratory of Molecular Pharmacology, Bethesda, MD, 20892, USA+1 301 435 2463; [email protected]
, PhD
Pages 901-904 | Published online: 10 May 2012

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Satish Kumar Gupta & Nutan. (2013) Clinical use of vaginal or rectally applied microbicides in patients suffering from HIV/AIDS. HIV/AIDS - Research and Palliative Care 5, pages 295-307.
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Rik Schrijvers & Zeger Debyser. (2012) Combinational therapies for HIV: a focus on EVG/COBI/FTC/TDF. Expert Opinion on Pharmacotherapy 13:13, pages 1969-1983.
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Eloïse Thierry, Eric Deprez & Olivier Delelis. (2017) Different Pathways Leading to Integrase Inhibitors Resistance. Frontiers in Microbiology 7.
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Mathieu Métifiot, Barry C. Johnson, Evgeny Kiselev, Laura Marler, Xue Zhi Zhao, Terrence R. BurkeJrJr, Christophe Marchand, Stephen H. Hughes & Yves Pommier. (2016) Selectivity for strand-transfer over 3′-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme–DNA interactions in the active site. Nucleic Acids Research 44:14, pages 6896-6906.
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Muriel Billamboz, Virginie Suchaud, Fabrice Bailly, Cedric Lion, Marie-Line Andréola, Frauke Christ, Zeger Debyser & Philippe Cotelle. (2016) 2-hydroxyisoquinoline-1,3(2 H ,4 H )-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4. European Journal of Medicinal Chemistry 117, pages 256-268.
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Asma Khatri & Marion J Skalweit. (2014) A rare case of immune reconstitution inflammatory syndrome presenting as secondary syphilis. International Journal of STD & AIDS 26:10, pages 749-751.
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Miłosz Parczewski & Magdalena Witak-Jędra. (2015) Clinical data and practical experience related to Stribild as an option in patients with HIV infection. HIV & AIDS Review 14:4, pages 104-108.
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Pinar Iyidogan & Karen Anderson. (2014) Current Perspectives on HIV-1 Antiretroviral Drug Resistance. Viruses 6:10, pages 4095-4139.
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Major Gooyit, Nancy Tricoche, Sara Lustigman & Kim D. Janda. (2014) Dual Protonophore–Chitinase Inhibitors Dramatically Affect O. volvulus Molting . Journal of Medicinal Chemistry 57:13, pages 5792-5799.
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Virginie Suchaud, Fabrice Bailly, Cedric Lion, Christina Calmels, Marie-Line Andréola, Frauke Christ, Zeger Debyser & Philippe Cotelle. (2014) Investigation of a Novel Series of 2-Hydroxyisoquinoline-1,3(2 H ,4 H )-diones as Human Immunodeficiency Virus Type 1 Integrase Inhibitors . Journal of Medicinal Chemistry 57:11, pages 4640-4660.
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David B. Hanna, Nancy A. Hessol, Elizabeth T. Golub, Jennifer M. Cocohoba, Mardge H. Cohen, Alexandra M. Levine, Tracey E. Wilson, Mary Young, Kathryn Anastos & Robert C. Kaplan. (2014) Increase in Single-Tablet Regimen Use and Associated Improvements in Adherence-Related Outcomes in HIV-Infected Women. JAIDS Journal of Acquired Immune Deficiency Syndromes 65:5, pages 587-596.
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Weiwei Xue, Huanxiang Liu & Xiaojun Yao. (2014) Molecular Modeling Study on the Allosteric Inhibition Mechanism of HIV-1 Integrase by LEDGF/p75 Binding Site Inhibitors. PLoS ONE 9:3, pages e90799.
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Ole J Bjerrum, Yvonne Gautam, Per H Honoré & Vasiliki Vana. (2014) Drug–drug combinations revisited. European Journal of Hospital Pharmacy 21:1, pages 8-12.
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Qi Chen, John K. Buolamwini, Jeremy C. Smith, Aixiu Li, Qin Xu, Xiaolin Cheng & Dongqing Wei. (2013) Impact of Resistance Mutations on Inhibitor Binding to HIV-1 Integrase. Journal of Chemical Information and Modeling 53:12, pages 3297-3307.
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Soundasse Munir, Sylvain Thierry, Frédéric Subra, Eric Deprez & Olivier Delelis. (2013) Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle. Retrovirology 10:1.
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Jens-Uwe Peters. (2013) Polypharmacology – Foe or Friend?. Journal of Medicinal Chemistry 56:22, pages 8955-8971.
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Md. Hossain, Md. Ali & Cha-Gyun Shin. (2013) Structural and Functional Insights into Foamy Viral Integrase. Viruses 5:7, pages 1850-1866.
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Muriel Billamboz, Virginie Suchaud, Fabrice Bailly, Cedric Lion, Jonas Demeulemeester, Christina Calmels, Marie-Line Andréola, Frauke Christ, Zeger Debyser & Philippe Cotelle. (2013) 4-Substituted 2-Hydroxyisoquinoline-1,3(2 H ,4 H )-diones as a Novel Class of HIV-1 Integrase Inhibitors . ACS Medicinal Chemistry Letters 4:7, pages 606-611.
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Ole J. Bjerrum, Yvonne Gautam, Esben J. Bjerrum, Merete Schmiegelow & Harrie C.M. Boonen. (2013) Medicines combinations options and regulatory hurdles. European Journal of Pharmaceutical Sciences 49:4, pages 659-663.
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Brian A. Johns, Takashi Kawasuji & Emile J. Velthuisen. 2013. Successful Strategies for the Discovery of Antiviral Drugs. Successful Strategies for the Discovery of Antiviral Drugs 149 188 .
Peter K. Quashie, Thibault Mesplède & Mark A. Wainberg. (2013) Evolution of HIV integrase resistance mutations. Current Opinion in Infectious Diseases 26:1, pages 43-49.
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Weiwei Xue, Xiaojie Jin, Lulu Ning, Meixia Wang, Huanxiang Liu & Xiaojun Yao. (2012) Exploring the Molecular Mechanism of Cross-Resistance to HIV-1 Integrase Strand Transfer Inhibitors by Molecular Dynamics Simulation and Residue Interaction Network Analysis. Journal of Chemical Information and Modeling 53:1, pages 210-222.
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Mathieu Métifiot, Christophe Marchand & Yves Pommier. 2013. Antiviral Agents. Antiviral Agents 75 105 .

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