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Drug Evaluations

Sorafenib in non-small cell lung cancer

, MD PhD, , MD & , MD
Pages 1417-1426 | Published online: 24 Jun 2012

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Khushwant S. Yadav, Hrushikesh C. Raut & Harsh P. Nijhawan. (2023) Inhalable spray-dried polycaprolactone-based microparticles of Sorafenib Tosylate with promising efficacy on A549 cells. Pharmaceutical Development and Technology 28:8, pages 755-767.
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Marybeth Sechler, Amber D Cizmic, Sreedevi Avasarala, Michelle Van Scoyk, Christine Brzezinski, Nicole Kelley, Rama Kamesh Bikkavilli & Robert A Winn. (2013) Non-small-cell lung cancer: molecular targeted therapy and personalized medicine – drug resistance, mechanisms, and strategies. Pharmacogenomics and Personalized Medicine 6, pages 25-36.
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Shanshan Jiang, Rong Wang, Xuan Zhang, Feihua Wu, Shengnan Li & Yongfang Yuan. (2020) Combination treatment of gemcitabine and sorafenib exerts a synergistic inhibitory effect on non‑small cell lung cancer in�vitro and in�vivo via the epithelial‑to‑mesenchymal transition process. Oncology Letters.
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Justyna Kutkowska, Leon Strzadala & Andrzej Rapak. (2017) Synergistic activity of sorafenib and betulinic acid against clonogenic activity of non‐small cell lung cancer cells. Cancer Science 108:11, pages 2265-2272.
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Zhihao Wang, Pengchao Hu, Fang Tang & Conghua Xie. (2016) HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells. Medical Oncology 33:5.
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Jia-Nian Chen, Xian-Fu Wang, Ting Li, De-Wen Wu, Xiao-Bo Fu, Guang-Ji Zhang, Xing-Can Shen & Heng-Shan Wang. (2016) Design, synthesis, and biological evaluation of novel quinazolinyl-diaryl urea derivatives as potential anticancer agents. European Journal of Medicinal Chemistry 107, pages 12-25.
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Yanmei Zhang, Micky D. Tortorella, Jinxi Liao, Xiaochu Qin, Tingting Chen, Jinfeng Luo, Jiantong Guan, John J. Talley & Zhengchao Tu. (2015) Synthesis and Evaluation of Novel Erlotinib–NSAID Conjugates as More Comprehensive Anticancer Agents. ACS Medicinal Chemistry Letters 6:10, pages 1086-1090.
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Ashraf Kareem El-Damasy, Seon Hee Seo, Nam-Chul Cho, Soon Bang Kang, Ae Nim Pae, Key-Sun Kim & Gyochang Keum. (2015) Design, synthesis, in-vitro antiproliferative activity and kinase profile of new picolinamide based 2-amido and ureido quinoline derivatives. European Journal of Medicinal Chemistry 101, pages 754-768.
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Sarah Fernandes Teixeira, Ricardo Alexandre de Azevedo, Maria Alejandra Clavijo Salomon, Salomão Dória Jorge, Débora Levy, Sérgio Paulo Bydlowski, Cecília Pessoa Rodrigues, Célia Regina Pizzo, José Alexandre Marzagão Barbuto & Adilson Kleber Ferreira. (2014) Synergistic anti-tumor effects of the combination of a benzofuroxan derivate and sorafenib on NCI-H460 human large cell lung carcinoma cells. Biomedicine & Pharmacotherapy 68:8, pages 1015-1022.
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Neelesh Sharma, Nathan Pennell, Myles Nickolich, Balazs Halmos, Patrick Ma, Tarek Mekhail, Pingfu Fu & Afshin Dowlati. (2014) Phase II trial of Sorafenib in conjunction with chemotherapy and as maintenance therapy in extensive-stage small cell lung cancer. Investigational New Drugs 32:2, pages 362-368.
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J Wan, T Liu, L Mei, J Li, K Gong, C Yu & W Li. (2013) Synergistic antitumour activity of sorafenib in combination with tetrandrine is mediated by reactive oxygen species (ROS)/Akt signaling. British Journal of Cancer 109:2, pages 342-350.
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