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Tyrosine kinase inhibitors as novel drugs for the treatment of diabetes

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Pages 751-763 | Published online: 25 May 2013

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Raj Kaushal & Mandeep Kaur. (2021) Bio-medical potential of chalcone derivatives and their metal complexes as antidiabetic agents: a review. Journal of Coordination Chemistry 74:4-6, pages 725-742.
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Tomi K Sawyer, Joe C Wu, Jonathon R Sawyer & Jessie M English. (2013) Protein kinase inhibitors: breakthrough medicines and the next generation. Expert Opinion on Investigational Drugs 22:6, pages 675-678.
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Ankush KumarBhupinder KumarRohit Bhatia. (2023) Design, Synthesis, Molecular Docking, and Biological Evaluation of Isatin-Based Fused Heterocycles As Epidermal Growth Factor Receptor Inhibitors. ASSAY and Drug Development Technologies 21:5, pages 222-233.
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Denis Amilton dos Santos, Higo Fernando Santos Souza, Ariel M. Silber, Tatiana de Arruda Campos Brasil de Souza & Andréa Rodrigues Ávila. (2023) Protein kinases on carbon metabolism: potential targets for alternative chemotherapies against toxoplasmosis. Frontiers in Cellular and Infection Microbiology 13.
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Wen Jian, Chun-Mei Wei, Jia-Hui Guan, Chang-Hua Mo, Yu-Tao Xu, Wen-Bo Zheng, Lang Li & Chun Gui. (2020) Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study. Journal of Translational Medicine 18:1.
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Fan Yang & Chu Wang. (2020) Profiling of post-translational modifications by chemical and computational proteomics. Chemical Communications 56:88, pages 13506-13519.
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Brittany M Duggan, Joseph F Cavallari, Kevin P Foley, Nicole G Barra & Jonathan D Schertzer. (2020) RIPK2 Dictates Insulin Responses to Tyrosine Kinase Inhibitors in Obese Male Mice. Endocrinology 161:8.
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Doaa A. Zaky, Walaa Wadie, Wagdy M. Eldehna, Ahmed M. El Kerdawy, Dalaal M. Abdallah & Hanan S. El Abhar. (2020) Modulation of endoplasmic reticulum stress response in gut-origin encephalopathy: Impact of vascular endothelial growth factor receptor-2 manipulation. Life Sciences 252, pages 117654.
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Amin Ardestani, Sijia Li, Karthika Annamalai, Blaz Lupse, Shirin Geravandi, Aleksandra Dobrowolski, Shan Yu, Siying Zhu, Tyler D. Baguley, Murali Surakattula, Janina Oetjen, Lena Hauberg-Lotte, Raquel Herranz, Sushil Awal, Delsi Altenhofen, Van Nguyen-Tran, Sean Joseph, Peter G. Schultz, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen & Kathrin Maedler. (2019) Neratinib protects pancreatic beta cells in diabetes. Nature Communications 10:1.
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Mahmoud M. Samaha, Eman Said & Hatem A. Salem. (2019) Nilotinib enhances β-islets integrity and secretory functions in a rat model of STZ-induced diabetes mellitus. European Journal of Pharmacology 860, pages 172569.
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Iram Faqir Muhammad, Yan Borné, Xue Bao, Olle Melander, Marju Orho-Melander, Peter M. Nilsson, Jan Nilsson & Gunnar Engström. (2019) Circulating HER2/ErbB2 Levels Are Associated With Increased Incidence of Diabetes: A Population-Based Cohort Study. Diabetes Care 42:8, pages 1582-1588.
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Kahlile Abboud, Sabrina Reis, Maria Martelli, Olivia Zordão, Fabiana Tannihão, Alessandra de Souza, Heloisa Assalin, Dioze Guadagnini, Guilherme Rocha, Mario Saad & Patricia Prada. (2019) Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans. Nutrients 11:3, pages 536.
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Sarah Akbib, Jordy Stichelmans, Geert Stangé, Zhidong Ling, Zerihun Assefa & Karine H. Hellemans. (2019) Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially. PLOS ONE 14:2, pages e0212210.
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Kristine Deano Abueg. (2017) Interprofessional Management of Toxicities Related to Cancer Precision Medicine. Seminars in Oncology Nursing 33:4, pages 376-383.
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Bruno Martino, Corrado Mammì, Claudia Labate, Silvia Rodi, Domenica Ielo, Manuela Priolo, Maurizio Postorino, Giovanni Tripepi, Francesca Ronco, Carmelo Laganà, Caterina Musolino, Marianna Greco, Giorgio La Nasa & Giovanni Caocci. (2017) Genetic risk of prediabetes and diabetes development in chronic myeloid leukemia patients treated with nilotinib. Experimental Hematology 55, pages 71-75.
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Z. Orfi, F. Waczek, F. Baska, I. Szabadkai, R. Torka, J. Hartmann, L. Orfi & A. Ullrich. (2017) Novel members of quinoline compound family enhance insulin secretion in RIN-5AH beta cells and in rat pancreatic islet microtissue. Scientific Reports 7:1.
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Xiang Li, Jonathan T. Cox, Weiliang Huang, Maureen Kane, Keqi Tang & Charles J. Bieberich. (2016) Quantifying Kinase-Specific Phosphorylation Stoichiometry Using Stable Isotope Labeling In a Reverse In-Gel Kinase Assay. Analytical Chemistry 88:23, pages 11468-11475.
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Agnieszka Karbownik, Edyta Szałek, Katarzyna Sobańska, Tomasz Grabowski, Anna Wolc & Edmund Grześkowiak. (2016) The alteration of pharmacokinetics of erlotinib and OSI420 in type 1 diabetic rabbits. Pharmacological Reports 68:5, pages 964-968.
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Kelly N. Chuh, Anna R. Batt & Matthew R. Pratt. (2016) Chemical Methods for Encoding and Decoding of Posttranslational Modifications. Cell Chemical Biology 23:1, pages 86-107.
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Nehal Mohsen Elsherbiny, Mohamed El-Sherbiny & Eman Said. (2015) Amelioration of experimentally induced diabetic nephropathy and renal damage by nilotinib. Journal of Physiology and Biochemistry 71:4, pages 635-648.
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Athanasios Fountas, Leonidas-Nikolaos Diamantopoulos & Agathocles Tsatsoulis. (2015) Tyrosine Kinase Inhibitors and Diabetes: A Novel Treatment Paradigm?. Trends in Endocrinology & Metabolism 26:11, pages 643-656.
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Anna M Czarnecka, Maciej Kawecki, Fei Lian, Jan Korniluk & Cezary Szczylik. (2015) Feasibility, efficacy and safety of tyrosine kinase inhibitor treatment in hemodialyzed patients with renal cell cancer: 10 years of experience. Future Oncology 11:16, pages 2267-2282.
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