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Investigational drugs for pruritus

, PhD, & , MD
Pages 1167-1179 | Published online: 02 Jul 2013

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Kateřina Vávrová. (2016) Emerging small-molecule compounds for treatment of atopic dermatitis: a review. Expert Opinion on Therapeutic Patents 26:1, pages 21-34.
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Bruno Vincenzi, Mike Trower, Ajay Duggal, Pamela Guglielmini, Peter Harris, David Jackson, Mario E Lacouture, Emiliangelo Ratti, Giuseppe Tonini, Andrew Wood & Sonja Ständer. (2020) Neurokinin-1 antagonist orvepitant for EGFRI-induced pruritus in patients with cancer: a randomised, placebo-controlled phase II trial. BMJ Open 10:2, pages e030114.
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Marta Peciña, Jordan F. Karp, Sanjay Mathew, Mark S. Todtenkopf, Elliot W. Ehrich & Jon-Kar Zubieta. (2018) Endogenous opioid system dysregulation in depression: implications for new therapeutic approaches. Molecular Psychiatry 24:4, pages 576-587.
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Rafael de Moraes Petecof, Alfredo Gragnani, Felipe Contoli Isoldi, Gibrán Elias Harcha Munoz, Samuel Marcos Ribeiro de Noronha, Silvana Aparecida Alves Corrêa & Lydia Masako Ferreira. (2018) Gene Expression of Neurotrophins and Their Receptors in Keloids. Annals of Plastic Surgery 81:6, pages 646-652.
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Jiali Zhong, Zhihong Liu, Xinxin Zhou & Jun Xu. (2017) Synergic Anti-Pruritus Mechanisms of Action for the Radix Sophorae Flavescentis and Fructus Cnidii Herbal Pair. Molecules 22:9, pages 1465.
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Kazuki M. Matsuda, Divya Sharma, Ariel R. Schonfeld & Shawn G. Kwatra. (2016) Gabapentin and pregabalin for the treatment of chronic pruritus. Journal of the American Academy of Dermatology 75:3, pages 619-625.e6.
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Paul L. Bigliardi, Yuri Dancik, Christine Neumann & Mei Bigliardi‐Qi. (2016) Opioids and skin homeostasis, regeneration and ageing – What's the evidence?. Experimental Dermatology 25:8, pages 586-591.
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C. Zeidler, E. Pogatzki-Zahn & S. Ständer. (2016) Recurrent cold-induced pruritic flush caused by small-fibre neuropathy in skin grafts. Journal of the European Academy of Dermatology and Venereology 30:2, pages 338-341.
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M Salaga, P R Polepally, M Zielinska, M Marynowski, A Fabisiak, N Murawska, K Sobczak, M Sacharczuk, J C Do Rego, B L Roth, J K Zjawiony & J Fichna. (2015) Salvinorin A analogues PR-37 and PR-38 attenuate compound 48/80-induced itch responses in mice. British Journal of Pharmacology 172:17, pages 4331-4341.
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Matti Aapro, Alexandra Carides, Bernardo L. Rapoport, Hans-Joachim Schmoll, Li Zhang & David Warr. (2015) Aprepitant and Fosaprepitant: A 10-Year Review of Efficacy and Safety. The Oncologist 20:4, pages 450-458.
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Sonja Ständer & Thomas A. Luger. 2015. Pharmacology of Itch. Pharmacology of Itch 237 255 .
Michael K. Trower, Amy Fisher, Neil Upton & Emiliangelo Ratti. (2014) Neurokinin‐1 receptor antagonist orvepitant is an effective inhibitor of itch‐associated response in a M ongolian gerbil model of scratching behaviour . Experimental Dermatology 23:11, pages 858-860.
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K. Maleki & E. Weisshaar. (2014) Arzneimittelinduzierter PruritusDrug-induced pruritus. Der Hautarzt 65:5, pages 436-442.
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