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Drug Evaluations

Panobinostat in lymphoid and myeloid malignancies

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Pages 1211-1223 | Published online: 03 Jul 2013

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Pierfausto Seneci. 2015. Chemical Modulators of Protein Misfolding and Neurodegenerative Disease. Chemical Modulators of Protein Misfolding and Neurodegenerative Disease 135 172 .
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Mark S. Butler, Avril A. B. Robertson & Matthew A. Cooper. (2014) Natural product and natural product derived drugs in clinical trials. Nat. Prod. Rep. 31:11, pages 1612-1661.
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