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New investigational drugs for the treatment of neuropathic pain

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Kinga Sałat, Adrian Podkowa, Natalia Malikowska & Jędrzej Trajer. (2017) Effect of pregabalin on fear-based conditioned avoidance learning and spatial learning in a mouse model of scopolamine-induced amnesia. Toxicology Mechanisms and Methods 27:3, pages 181-190.
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Yukinori Nagakura. (2017) The need for fundamental reforms in the pain research field to develop innovative drugs. Expert Opinion on Drug Discovery 12:1, pages 39-46.
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Edward C Emery, Ana Paula Luiz & John N Wood. (2016) Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief. Expert Opinion on Therapeutic Targets 20:8, pages 975-983.
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Kinga Sałat, Jadwiga Witalis, Monika Zadrożna, Zbigniew Sołtys, Barbara Nowak, Barbara Filipek, Krzysztof Więckowski & Barbara Malawska. (2015) 3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one and pregabalin attenuate tactile allodynia in the mouse model of chronic constriction injury. Toxicology Mechanisms and Methods 25:7, pages 514-523.
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Kinga Sałat, Anna Jakubowska & Katarzyna Kulig. (2015) Cebranopadol: a first-in-class potent analgesic agent with agonistic activity at nociceptin/orphanin FQ and opioid receptors. Expert Opinion on Investigational Drugs 24:6, pages 837-844.
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Articles from other publishers (28)

Paula Zaręba, Kamil Łątka, Gabriela Mazur, Beata Gryzło, Anna Pasieka, Justyna Godyń, Dawid Panek, Anna Skrzypczak-Wiercioch, Georg C. Höfner, Gniewomir Latacz, Maciej Maj, Alba Espargaró, Raimon Sabaté, Krzysztof Jóźwiak, Klaus T. Wanner, Kinga Sałat, Barbara Malawska, Katarzyna Kulig & Marek Bajda. (2023) Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease. European Journal of Medicinal Chemistry 261, pages 115832.
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Małgorzata Zygmunt, Marietta Ślusarczyk, Agnieszka Jankowska, Artur Świerczek, Adrian Bryła, Szczepan Mogilski, Grzegorz Kazek, Jacek Sapa, Elżbieta Wyska & Grażyna Chłoń-Rzepa. (2022) Evaluation of analgesic and anti-inflammatory activity of purine-2,6-dione-based TRPA1 antagonists with PDE4/7 inhibitory activity. Pharmacological Reports 74:5, pages 982-997.
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Zhenhua Cai, Lini Quan, Xiaotao Chang, Zhijie Qiu & Huacheng Zhou. (2022) High-voltage long-duration pulsed radiofrequency attenuates neuropathic pain in CCI rats by inhibiting Cav2.2 in spinal dorsal horn and dorsal root ganglion. Brain Research 1785, pages 147892.
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Paula Zaręba, Kinga Sałat, Georg C. Höfner, Kamil Łątka, Marek Bajda, Gniewomir Latacz, Krzysztof Kotniewicz, Anna Rapacz, Adrian Podkowa, Maciej Maj, Krzysztof Jóźwiak, Barbara Filipek, Klaus T. Wanner, Barbara Malawska & Katarzyna Kulig. (2021) Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity. European Journal of Medicinal Chemistry 221, pages 113512.
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Christopher M Lam, Hadi Zayed & Dawood Sayed. (2021) High frequency dorsal column spinal cord stimulation for management of erythromelalgia. BMJ Case Reports 14:8, pages e244758.
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Mauro Zappaterra & Udai Nanda. 2021. Pain Care Essentials and Innovations. Pain Care Essentials and Innovations 255 267 .
Jolanta Obniska, Małgorzata Góra, Anna Rapacz, Kinga Sałat, Sabina Rybka, Michał Abram, Marcin Jakubiec & Krzysztof Kamiński. (2020) Synthesis, anticonvulsant, and antinociceptive activity of new 3‐(3‐methyl‐2,5‐dioxo‐3‐phenylpyrrolidin‐1‐yl)propanamides and 3‐phenyl‐butanamides. Archiv der Pharmazie 354:1, pages 2000225.
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Srinivasa N. Raja, Matthias Ringkamp, Yun Guan & James N. Campbell. (2020) John J. Bonica Award Lecture: Peripheral neuronal hyperexcitability: the “low-hanging” target for safe therapeutic strategies in neuropathic pain. Pain 161:Supplement 1, pages S14-S26.
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Kinga Sałat. (2020) Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity. Pharmacological Reports 72:3, pages 508-527.
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Maria Cristina Caroleo, Antonella Brizzi, Maria De Rosa, Ankur Pandey, Luca Gallelli, Mariateresa Badolato, Gabriele Carullo & Erika Cione. (2020) Targeting Neuropathic Pain: Pathobiology, Current Treatment and Peptidomimetics as a New Therapeutic Opportunity. Current Medicinal Chemistry 27:9, pages 1469-1500.
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Paula Zaręba, Beata Gryzło, Katarzyna Malawska, Kinga Sałat, Georg C. Höfner, Alicja Nowaczyk, Łukasz Fijałkowski, Anna Rapacz, Adrian Podkowa, Anna Furgała, Paweł Żmudzki, Klaus T. Wanner, Barbara Malawska & Katarzyna Kulig. (2020) Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. European Journal of Medicinal Chemistry 188, pages 111920.
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Bill McCarberg & John Peppin. (2019) Pain Pathways and Nervous System Plasticity: Learning and Memory in Pain. Pain Medicine 20:12, pages 2421-2437.
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Seoyon Yang & Min Cheol Chang. (2019) Chronic Pain: Structural and Functional Changes in Brain Structures and Associated Negative Affective States. International Journal of Molecular Sciences 20:13, pages 3130.
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Grażyna Chłoń-Rzepa, Marietta Ślusarczyk, Agnieszka Jankowska, Alicja Gawalska, Adam Bucki, Marcin Kołaczkowski, Artur Świerczek, Krzysztof Pociecha, Elżbieta Wyska, Małgorzata Zygmunt, Grzegorz Kazek, Kinga Sałat & Maciej Pawłowski. (2018) Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain. European Journal of Medicinal Chemistry 158, pages 517-533.
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Jie Yang, Man-Xiu Xie, Li Hu, Xiao-Fang Wang, Jie-Zhen Mai, Yong-Yong Li, Ning Wu, Cheng Zhang, Jin Li, Rui-Ping Pang & Xian-Guo Liu. (2018) Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury. Brain, Behavior, and Immunity 71, pages 52-65.
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Robert P. Yezierski & Per Hansson. (2018) Inflammatory and Neuropathic Pain From Bench to Bedside: What Went Wrong?. The Journal of Pain 19:6, pages 571-588.
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Akihiko S. Kato & Jeffrey M. Witkin. (2018) Protein complexes as psychiatric and neurological drug targets. Biochemical Pharmacology 151, pages 263-281.
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Nebojsa Nick KnezevicAjay YekkiralaTony L. Yaksh. (2017) Basic/Translational Development of Forthcoming Opioid- and Nonopioid-Targeted Pain Therapeutics. Anesthesia & Analgesia 125:5, pages 1714-1732.
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Anthony J. Roecker, Melissa Egbertson, Kristen L.G. Jones, Robert Gomez, Richard L. Kraus, Yuxing Li, Amy Jo Koser, Mark O. Urban, Rebecca Klein, Michelle Clements, Jacqueline Panigel, Christopher Daley, Jixin Wang, Eleftheria N. Finger, John Majercak, Vincent Santarelli, Irene Gregan, Matthew Cato, Tracey Filzen, Aneta Jovanovska, Ying-Hong Wang, Deping Wang, Leo A. Joyce, Edward C. Sherer, Xuanjia Peng, Xiu Wang, Haiyan Sun, Paul J. Coleman, Andrea K. Houghton & Mark E. Layton. (2017) Discovery of selective, orally bioavailable, N -linked arylsulfonamide Na v 1.7 inhibitors with pain efficacy in mice. Bioorganic & Medicinal Chemistry Letters 27:10, pages 2087-2093.
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Łukasz Fijałkowski, Kinga Sałat, Adrian Podkowa, Paula Zaręba & Alicja Nowaczyk. (2017) Potential role of selected antiepileptics used in neuropathic pain as human GABA transporter isoform 1 (GAT1) inhibitors—Molecular docking and pharmacodynamic studies. European Journal of Pharmaceutical Sciences 96, pages 362-372.
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P. Beswick. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 65 130 .
Douglas M. Lopes & Stephen B. McMahon. (2015) Ultraviolet Radiation on the Skin: A Painful Experience?. CNS Neuroscience & Therapeutics 22:2, pages 118-126.
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Ana Paula Luiz & John N. Wood. 2016. Pharmacological Mechanisms and the Modulation of Pain. Pharmacological Mechanisms and the Modulation of Pain 153 178 .
Thomas J. Smith & Joe O’Neil. 2016. Supportive Cancer Care. Supportive Cancer Care 111 126 .
Zhaoli Tang, Zhao Chen, Beisha Tang & Hong Jiang. (2015) Primary erythromelalgia: a review. Orphanet Journal of Rare Diseases 10:1.
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P. Lozeron & N. Kubis. (2015) Prise en charge de la douleur neuropathique. La Revue de M?decine Interne 36:7, pages 480-486.
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A. Jonsson, R. Fransson, Y. Haramaki, A. Skogh, E. Brolin, H. Watanabe, G. Nordvall, M. Hallberg, A. Sandstr?m & F. Nyberg. (2015) Small constrained SP1?7 analogs bind to a unique site and promote anti-allodynic effects following systemic injection in mice. Neuroscience 298, pages 112-119.
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Parneet Kaur, Arunachalam Muthuraman & Jaspreet Kaur. (2014) Ameliorative potential of angiotensin-converting enzyme inhibitor (ramipril) on chronic constriction injury of sciatic nerve induced neuropathic pain in mice. Journal of the Renin-Angiotensin-Aldosterone System 16:1, pages 103-112.
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