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Phase II drugs under clinical investigation for the treatment of chronic constipation

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Marzieh Daniali, Shekoufeh Nikfar & Mohammad Abdollahi. (2020) An overview of interventions for constipation in adults. Expert Review of Gastroenterology & Hepatology 14:8, pages 721-732.
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Marzieh Daniali, Shekoufeh Nikfar & Mohammad Abdollahi. (2020) Evaluating naloxegol for the treatment of opioid-induced constipation. Expert Opinion on Pharmacotherapy 21:8, pages 883-891.
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Shilan Mozaffari, Shekoufeh Nikfar, Marzieh Daniali & Mohammad Abdollahi. (2020) The pharmacological management of constipation in patients with Parkinson’s disease: a much-needed relief. Expert Opinion on Pharmacotherapy 21:6, pages 701-707.
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Marzieh Daniali, Shekoufeh Nikfar & Mohammad Abdollahi. (2019) An overview of the efficacy and safety of prucalopride for the treatment of chronic idiopathic constipation. Expert Opinion on Pharmacotherapy 20:17, pages 2073-2080.
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Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi. (2018) Methylnaltrexone bromide for the treatment of opioid-induced constipation. Expert Opinion on Pharmacotherapy 19:10, pages 1127-1135.
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Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi. (2018) Investigational opioid antagonists for treating opioid-induced bowel dysfunction. Expert Opinion on Investigational Drugs 27:3, pages 235-242.
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Gabrio Bassotti, Dario Gambaccini & Massimo Bellini. (2016) Velusetrag for the treatment of chronic constipation. Expert Opinion on Investigational Drugs 25:8, pages 985-990.
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Ilan J.N. Koppen, Carlo Di Lorenzo, Miguel Saps, Phil G. Dinning, Desale Yacob, Marc A. Levitt & Marc A. Benninga. (2016) Childhood constipation: finally something is moving!. Expert Review of Gastroenterology & Hepatology 10:1, pages 141-155.
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Articles from other publishers (9)

Xiao-yan Chang, Yuan-yuan Liu, Meng-meng Hu, You-qian Liu, Cui-hua Jiang, Qi Wang, Qiao-mei Jin, Dong-jian Zhang, Zhi-qi Yin & Jian Zhang. (2022) Comparative effects of different enzymatic hydrolysates of konjac glucomannan on gut flora and constipation in rats. Food & Function 13:16, pages 8717-8729.
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Qi Zhao, Yan-Yan Chen, Ding-Qiao Xu, Shi-Jun Yue, Rui-Jia Fu, Jie Yang, Li-Ming Xing & Yu-Ping Tang. (2021) Action Mode of Gut Motility, Fluid and Electrolyte Transport in Chronic Constipation. Frontiers in Pharmacology 12.
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Jakub Włodarczyk, Anna Waśniewska, Jakub Fichna, Adam Dziki, Łukasz Dziki & Marcin Włodarczyk. (2021) Current Overview on Clinical Management of Chronic Constipation. Journal of Clinical Medicine 10:8, pages 1738.
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Ming Li, Qian Wang, Yong Li, Shengtian Cao, Yingjun Zhang, Zhongqing Wang, Guozhu Liu, Jing Li & Baohua Gu. (2020) Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges. Pharmacology & Therapeutics 212, pages 107539.
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Emanuele Sinagra, Gaetano Cristian Morreale, Ghazaleh Mohammadian, Giorgio Fusco, Valentina Guarnotta, Giovanni Tomasello, Francesco Cappello, Francesca Rossi, Georgios Amvrosiadis & Dario Raimondo. (2017) New therapeutic perspectives in irritable bowel syndrome: Targeting low-grade inflammation, immuno-neuroendocrine axis, motility, secretion and beyond. World Journal of Gastroenterology 23:36, pages 6593-6627.
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Eamonn M M Quigley. (2015) Prokinetics in the Management of Functional Gastrointestinal Disorders. Journal of Neurogastroenterology and Motility 21:3, pages 330-336.
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Chunhuan Jiang, Qinglong Xu, Xiaoan Wen & Hongbin Sun. (2015) Current developments in pharmacological therapeutics for chronic constipation. Acta Pharmaceutica Sinica B 5:4, pages 300-309.
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Mahin Elsagh, Mohammad Reza Fartookzadeh, Mohammad Kamalinejad, Majid Anushiravani, Awat Feizi, Farshad Amini Behbahani, Rahmatollah Rafiei, Akbar Arjmandpour & Peyman Adibi. (2015) Efficacy of the Malva sylvestris L. flowers aqueous extract for functional constipation: A placebo-controlled trial. Complementary Therapies in Clinical Practice 21:2, pages 105-111.
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Han Seung RyuSuck Chei Choi. (2015) Recent Updates on the Treatment of Constipation. Intestinal Research 13:4, pages 297.
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